Inhibitory effects of T-cell stimulation and co-stimulation observed at high concentrations of plate-bound antibodies

Journal of Immunological Methods

Volumn 255, Issue 1-2, 2001, Pages 23-26

  Lesage, Sylvie ^a,b   Charron, Josée ^a   Hugo, Patrice ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^b Biology and Environment   (Australia)

Author keywords

Antibody; In vitro assay; Stimulation; T cells; Thymocyte

Indexed keywords

CD28 ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANTIBODY BLOOD LEVEL; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; THYMOCYTE;

ANTIBODIES; ANTIGENS, CD28; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 0035452486     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(01)00415-X     Document Type: Article

References (6)

1. Formation of TCR dimers/trimers as a crucial step for T cell activation
2. Immune responses in the absence of costimulation: Viruses know the trick
3. Initiation of signal transduction through the TCR requires the peptide multivalent engagement of MHC ligands
4. Transfected Droshopila cells as probe for defining the minimal requirements for stimulating unprimed CD8+T cells
5. Biophysical studies of T-cell receptors and their ligands
6. Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition