The enantioselective immunoaffinity extraction of an optically active ibuprofen-modified peptide fragment

Analytical Biochemistry

Volumn 296, Issue 1, 2001, Pages 63-72

  Ikegawa, Shigeo ^a   Isriyanthi, Ni Made Ria ^a   Nagata, Masanori ^a   Yahata, Kenji ^a   Ito, Hiromi ^a   Mano, Nariyasu ^a   Goto, Junichi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

2 aryl propionic acid; Acyl glucuronide; Drug protein adduct; MALDI TOFMS; Proteolytic digestion

Indexed keywords

AMINO ACIDS; ANTIBODIES; ANTIGEN-ANTIBODY REACTIONS; ENANTIOSELECTIVITY; EXTRACTION; MAMMALS; PROPIONIC ACID;

BOVINE SERUM ALBUMINS; DRUG-PROTEIN ADDUCT; GLUCURONIDES; IMMOBILIZED ANTIBODIES; IMMUNOAFFINITY EXTRACTIONS; MALDI-TOFMS; PROTEOLYTIC DIGESTION; STRUCTURAL CHARACTERIZATION;

PEPTIDES;

AMMONIUM ACETATE; BETA ALANINE; BUFFER; GLUCURONIDE; IBUPROFEN; METHANOL; METHYL GROUP; PEPTIDE; PROPIONIC ACID DERIVATIVE; SERUM ALBUMIN;

ANTIBODY AFFINITY; ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENANTIOMER; EXTRACTION; HYPERSENSITIVITY; IMMUNIZATION; IMMUNOADSORPTION; IONIZATION; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR RECOGNITION; OPTICAL ROTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ISOLATION; RABBIT; STRUCTURE ANALYSIS;

BOVINAE; ORYCTOLAGUS CUNICULUS;

EID: 0035450801     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2001.5198     Document Type: Article

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