The srs2 suppressor of UV sensitivity acts specifically on the RAD5- and MMS2-dependent branch of the RAD6 pathway

Nucleic Acids Research

Volumn 29, Issue 17, 2001, Pages 3487-3494

  Ulrich, H D ^a  

^a MAX PLANCK INSTITUTE FOR TERRESTRIAL MICROBIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DNA; HELICASE; MESYLIC ACID METHYL ESTER; RAD5 PROTEIN; RAD6 PROTEIN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENE CONVERSION; GENE DELETION; GENE MUTATION; GENE REPRESSION; GENETIC RECOMBINATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; SACCHAROMYCES CEREVISIAE; STAGING; TRANSCRIPTION REGULATION; ULTRAVIOLET RADIATION;

SACCHAROMYCES CEREVISIAE;

EID: 0035445946     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.17.3487     Document Type: Article

References (56)

1. DNA Repair and Mutagenesis
2. DNA repair genes and proteins of Saccharomyces cerevisiae
3. The RAD6 DNA repair pathway in Saccharomyces cerevisiae: What does it do and how does it do it?
4. The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme
5. Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions
6. The RAD6 gene and protein of Saccharomyces cerevisiae
7. Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding and ATP hydrolytic activities
8. Characterization of postreplication repair in Saccharomyces cerevisiae and effects of rad6, rad18, rev3 and rad52 mutations
9. A similar defect in UV-induced mutagenesis conferred by the rad6 and rad18 mutations of Saccharomyces cerevisiae
10. REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase
11. Thymine-thymine dimer bypass by yeast DNA polymerase ζ
12. The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism
13. Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability
14. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη
15. Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome
16. Ultraviolet-induced reversion of cycl alleles in radiation sensitive strains of yeast. II. rev2 mutant strains
17. Analysis of mutagenic DNA repair in a thermoconditional mutant of Saccharomyces cerevisiae. IV. Influence of DNA replication and excision repair on REV2 dependent UV-mutagenesis and repair
18. Mutants of yeast defective in mutations induced by ultraviolet light
19. Yeast DNA repair protein RAD5 that promotes instability of simple repetitive sequences is a DNA-dependent ATPase
20. SWI2/SNF2 and related proteins: ATP-driven motors that disrupt protein-DNA interactions
21. Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair
22. The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways
23. MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway
24. Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains
25. A ubiquitin mutant with specific defects in DNA repair and multiubiquitination
26. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair
27. Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations
28. RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene
29. Metabolic suppressors of trimethoprim and ultraviolet light sensitivities of Saccharomyces cerevisiae rad6 mutants
30. The hyper-gene conversion hpr5-1 mutation of Saccharomyces cerevisiae is an allele of the SRS2/RADH gene
31. The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channelling DNA lesions into the RAD52 DNA repair pathway
32. Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae
33. Deletion of the SRS2 gene suppresses elevated recombination and DNA damage sensitivity in rad5 and rad18 mutants of Sacchromyces cerevisiae
34. Requirement for the SRS2 DNA helicase gene in non-homologous end joining in yeast
35. Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Δ with other DNA repair genes in Saccharomyces cerevisiae
36. Analysis of mitotic and meiotic defects in Saccharomyces cerevisiae SRS2 DNA helicase mutants
37. Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae
38. The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation and other stresses
39. Epitope tagging of yeast genes using a PCR-based strategy: More tags and improved practical routines
40. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
41. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae
42. Expression of the Saccharomyces cerevisiae DNA repair gene RAD6 that encodes a ubiquitin conjugating enzyme, increases in response to DNA damage and in meiosis but remains constant during the mitotic cell cycle
43. Transcript levels of the Saccharomyces cerevisiae DNA repair gene RAD18 increase in UV irradiated cells and during meiosis but not during the mitotic cell cycle
44. Genetic interactions between mutants of the 'error-prone' repair group of Saccharomyces cerevisiae and their effect on recombination and mutagenesis
45. UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae
46. Global response of Saccharomyces cerevisiae to an alkylating agent
47. Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins
48. Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase
49. The complexity of the interactions between RAD52 and SRS2
50. Requirement of yeast SGS1 and SRS2 genes for replication and transcription
51. Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases
52. A radical solution to death
53. POL32, a subunit of the Saccharomyces cerevisiae DNA polymerase δ. defines a link between DNA replication and the mutagenic bypass repair pathway
54. Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae