Critical implication of transmembrane Phe310, possibly in conjunction with Trp279, in the rat gonadotropin-releasing hormone receptor activation

Biochemical Pharmacology

Volumn 62, Issue 3, 2001, Pages 329-334

  Chauvin, Stéphanie ^a   Hibert, Marcel ^b   Bérault, Annette ^a   Counis, Raymond ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b Laboratoire de Pharmacochimie   (France)

Author keywords

Aromatic residues; GnRH binding; GnRH receptor; Receptor activation internalization; Three dimensional modeling; Transmembrane helix

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GONADORELIN RECEPTOR; INOSITOL PHOSPHATE; MEMBRANE PROTEIN; PHENYLALANINE; PHOSPHOLIPASE C; TRYPTOPHAN;

ARTICLE; BINDING AFFINITY; ENZYME ACTIVATION; ENZYME CONFORMATION; HORMONE RECEPTOR INTERACTION; INTERNALIZATION; MUTATION; PRIORITY JOURNAL; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHENYLALANINE; PROTEIN CONFORMATION; RATS; RECEPTORS, LHRH; SEQUENCE HOMOLOGY, AMINO ACID; TRYPTOPHAN;

EID: 0035427638     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00675-X     Document Type: Article

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