The influence of surface charges on quaternary ammonium block of Shaker K+ channels

Journal of Membrane Biology

Volumn 182, Issue 3, 2001, Pages 233-243

  Quinn, C C ^a   Begenisich, T ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Electrostatic; Gallamine; Ionic strength dependence; Surface charge density; Surface potential; Tetraethylammonium

Indexed keywords

AMINO ACID; AMMONIA; ELECTROLYTE; GALLAMINE; POTASSIUM CHANNEL; POTASSIUM ION; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; DENSITY; ELECTRICITY; GENE MUTATION; ION CURRENT; IONIC STRENGTH; NONHUMAN; OOCYTE; XENOPUS;

ANIMALS; ELECTROPHYSIOLOGY; GALLAMINE TRIETHIODIDE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTATION; NEUROMUSCULAR NONDEPOLARIZING AGENTS; OOCYTES; OSMOLAR CONCENTRATION; POTASSIUM CHANNELS; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; TETRAETHYLAMMONIUM; XENOPUS LAEVIS;

ANIMALIA;

EID: 0035425021     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-001-0047-8     Document Type: Article

References (27)

1. A contribution to the theory of electrocapillarity
2. Species-dependent effect of neuromuscular blocking agents
3. + channels
4. + channels. Effects of strontium on five cloned channels expressed in Xenopus oocytes
5. Influence of protein surface charge on the bimolecular kinetics of a potassium channel peptide inhibitor
6. Maintenance of Xenopus laevis and oocyte injection
7. Sur la constitution de la charge electrique a la surface d'un electrolyte
8. The electrical double layer and the theory of electrocapillarity
9. + channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines
10. The aromatic binding site for tetraethylammonium ion on potassium channels
11. Biophysical and molecular mechanisms of Shaker potassium channel inactivation
12. The selectivity of different external binding sites for quaternary ammonium ions in cloned potassium channels
13. Interaction between external tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels
14. + channels
15. + channel
16. Divalent ions and the surface potential of charged phospholipid membranes
17. + channel in planar lipid bilayers
18. Electrostatic mutations in iberiotoxin as a unique tool for probing the electrostatic structure of the maxi-K channel outer vestibule
19. + channel
20. Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels
21. Effects of gallamine triethiodide ('Flaxedil') on membrane currents in amphibian and mammalian peripheral nerve
22. The theory of the electrolytic double-layer
23. + channels
24. Interaction between quaternary ammonium ions in the pore of potassium channels. Evidence against an electrostatic repulsion mechanism