Fluorescence excitation spectroscopy for the measurement of epidermal proliferation

Photochemistry and Photobiology

Volumn 74, Issue 1, 2001, Pages 96-102

  Doukas, Apostolos G ^a   Soukos, Nikolaos S ^a   Babusis, Stephanie ^b   Appa, Yohini ^b   Kollias, Nikiforos ^c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Neutrogena Corporation   (United States)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYACID; COLLAGEN; GLYCOLIC ACID; TRYPTOPHAN;

ADULT; ARTICLE; CELL PROLIFERATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; CROSS LINKING; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; EPIDERMIS; FEMALE; FLUORESCENCE SPECTROSCOPY; FOREARM; HUMAN; HUMAN EXPERIMENT; LIGHT INTENSITY; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SKIN FUNCTION; SPECTRUM;

ADULT; CELL DIVISION; DOUBLE-BLIND METHOD; FEMALE; GLYCOLATES; HUMANS; KERATOLYTIC AGENTS; MALE; MIDDLE AGED; PHOTOBIOLOGY; SKIN; SPECTROMETRY, FLUORESCENCE;

EID: 0035413203     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2001)074<0096:FESFTM>2.0.CO;2     Document Type: Article

References (19)

1. Johannesson, A. and H. Hammar (1978) Measurement of the horny layer turnover after staining with dansyl chloride: description of a new method. Acta Dermatol. Venereol. 58, 76-79.
2. Roberts, D. L., R. Marshall and R. Marks (1980) Detection of the action of salicylic acid on the normal stratum corneum. Br. J. Dermatol. 103, 191-196.
3. Marks, R., I. Hamami, A. Caunt and R. J. Marshal (1984) A simplified method for measurement of desquamation using dansyl chloride fluorescence. Br. J. Dermatol. 111, 265-270.
4. Ridge, B. D., M. D. Batt, H. E. Palmer and A. Jarrett (1988) The dansyl chloride technique for stratum corneum renewal as an indicator of changes in epidermal mitotic activity following topical treatment. Br. J. Dermatol. 118, 167-174.
5. Kollias, N., R. Gillies, M. Moran, I. Kochevar and R. R. Anderson (1998) Endogenous skin fluorescence includes bands that may serve as quantitative markers of aging and photoaging. J. Investig. Dermatol. 111, 776-781.
6. Brancaleon, N., G. Lin and N. Kollias (1999) The in vivo fluorescence of tryptophan moieties in human skin increases with UV exposure and is a marker for epidermal proliferation. J. Investig. Dermatol. 113, 977-982.
7. Gillies, R., G. Zonios, R. R. Anderson and N. Kollias (2000) Fluorescence excitation spectroscopy provides information about human skin in vivo. J. Investig. Dermatol. 115, 704-707.
8. Hoerman, K. C. (1971) The optical properties of the skin and its biochemical substituents. In Biophysical Properties of the Skin (Edited by H. R. Elden), pp. 153-186. Wiley, New York.
9. Leffell, D. J., M. L. Stetz, L. M. Milstone and L. I. Deckelbaum (1988) In vivo fluorescence of human skin - a potential marker of photoaging. Arch. Dermatol. 124, 1514-1518.
10. Labella, F. C. (1971) Cross-links in elastin and collagen. In Biophysical Properties of the Skin (Edited by H. R. Elden), pp. 243-301. Wiley, New York.
11. Kollias, N. (1995) The physical basis of skin color and its evaluation. Clin. Dermatol. 13, 361-367.
12. Young, A. R. (1997) Chromophores in human skin. Phys. Med. Biol. 42, 789-802.
13. Lucke, T., R. Choudhry, R. Thom, I. S. Selmer, A. D. Burden and M. B. Hopdgins (1999) Upregulation ot connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium. J. Investig. Dermatol. 112, 354-361.
14. Gerdes, J., H. Lemke and H. Baisch (1984) Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol. 133, 1710-1715.
15. Brancaleon, L., A. J. Durkin, J. H. Tu, G. Menaker, J. D. Fallonand and N. Kollias (2001) In vivo fluorescence spectroscopy of nonmelanoma skin cancer. Photochem. Photobiol. 73, 178-183.
16. Zhang, J. C., H. E. Savage, P. G. Sacks, T. Delohery, R. R. Alfano, A. Katz and S. P. Schantz (1997) Inmate cellular fluorescence reflects alterations in cellular proliferation. Lasers Surg. Med. 20, 319-331.
17. Rajadhyaksha, M., S. González, J. M. Zavislan, R. R. Anderson and R. H. Webb (1998) In vivo confocal scanning laser microscopy of the human skin II. Advances in instrumentation and comparison with histology. J. Investig. Dermatol. 113, 293-303.
18. Zeng, H., C. MacAulay, D. I. McLean and B. Palcic (1995) Spectroscopic and microscopic characteristics of human skin autofluorescence emission. Photochem. Photobiol. 61, 639-645.
19. Richards-Kortum, R. and E. Sevick-Muraka (1996) Quantitative optical spectroscopy for tissue diagnosis. Annu. Rev. Phys. Chem. 47, 555-606.