Validation of the NucliSens Extractor in combination with the hepatitis C virus Cobas Amplicor 2.0 assay in four laboratories in the Netherlands utilizing nucleic acid amplification technology for blood screening

Vox Sanguinis

Volumn 81, Issue 1, 2001, Pages 12-20

  Cuijpers, H T M ^a   Molijn, M H J ^b   Bos, H J ^c   Peeters, A P W ^d   Van Der Poel, C L ^e   Lelie, P N ^a,e  

^a Sanquin CLB   (Netherlands)

^b Sanquin Blood Bank   (Netherlands)

^c Sanquin Blood Bank   (Netherlands)

^d Sanquin Bloedbank Regio Nordoost Groningen   (Netherlands)

^e CENTRAL LABORATORY   (Netherlands)

Author keywords

95 Detection limit; HCV NAT method; Robustness; Run control; Validation

Indexed keywords

VIRUS RNA;

ABSORPTION; ARTICLE; ASSAY; BLOOD ANALYSIS; BLOOD COMPONENT THERAPY; BLOOD DONOR; COMPUTER PROGRAM; DILUTION; EXTRACTION; GENOTYPE; HEPATITIS C VIRUS; HUMAN; LABORATORY TEST; NETHERLANDS; NUCLEIC ACID AMPLIFICATION; PERFORMANCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUALITY CONTROL; RNA ISOLATION; SCREENING; VALIDATION PROCESS; VIRAL CONTAMINATION; VIREMIA; VIRUS DETECTION; VIRUS GENOME;

EQUIPMENT FAILURE; FALSE NEGATIVE REACTIONS; HEPACIVIRUS; HEPATITIS C; HUMANS; MASS SCREENING; NETHERLANDS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; REPRODUCIBILITY OF RESULTS; RNA, VIRAL; SENSITIVITY AND SPECIFICITY;

EID: 0035412619     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.2001.00055.x     Document Type: Article

References (9)

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