Characterisation of ventricular myocyte shortening after administration of streptozotocin (STZ) to neonatal rats

Archives of Physiology and Biochemistry

Volumn 109, Issue 3 SPEC ISS., 2001, Pages 200-205

  Howarth, F C ^a,b   Qureshi, M A ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Diabetes; Neonatal; Shortening; Streptozotocin; Ventricular myocytes

Indexed keywords

GLUCOSE; INSULIN;

ADOLESCENT; AGE; ANIMAL CELL; ANIMAL MODEL; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROSTIMULATION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HEART CONTRACTION; HEART MUSCLE CELL; MALE; MUSCLE LENGTH; MUSCLE RELAXATION; NEWBORN; NONHUMAN; RAT; STREPTOZOCIN DIABETES; WEIGHT GAIN;

ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; ELECTROPHYSIOLOGY; HEART VENTRICLES; MYOCARDIUM; ORGAN SIZE; RATS; TIME FACTORS;

ANIMALIA;

EID: 0035412505     PISSN: 13813455     EISSN: None     Source Type: Journal    
DOI: 10.1076/apab.109.3.200.11598     Document Type: Conference Paper

References (18)

1. Dhalla NS, Pierce GN, Innes IR, Beamish RE (1985): Pathogenesis of cardiac dysfunction in diabetes mellitus. Can J Cardiol 1: 263-281.
2. Fein FS, Sonnenblick EH (1985): Diabetic cardiomyopathy. Prog Cardiovasc Dis 27: 255-270.
3. 2+] during inotropic interventions in isolated rat myocytes. J Physiol 437: 351-375.
4. Howarth FC, Qureshi MA, Bracken NK, Winlow W, Singh J (2001): Time-dependent effects of streptozotocin-induced diabetes on contraction of ventricular myocytes from rat heart. Emirates Medical Journal 19(1): 35-41.
5. 2+ transients and cell shortening in diabetic rat ventricular myocytes. Jpn Circ J 57: 449-457.
6. Okayama H, Hamada M, Hiwada K (1994): Contractile dysfunction in the diabetic-rat heart is an intrinsic abnormality of the cardiac myocyte. Clin Sci (Colch) 86: 257-262.
7. Pierce GN, Maddaford TG, Russell JC (1997): Cardiovascular dysfunction in insulin-dependent and non-insulin-dependent animal models of diabetes mellitus. Canadian J Physiol & Pharmacol 75: 343-350.
8. Portha B, Blondel O, Serradas P, McEvoy R, Giroix MH, Kergoat M, Bailbe D (1989): The rat models of non-insulin-dependent diabetes induced by neonatal streptozotocin. Diabetes Metab 15: 61-75.
9. Portha B, Picon L, Rosselin G (1979): Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes. Diabetologia 17: 371-377.
10. Regan TJ (1983): Congestive heart failure in the diabetic. Annu Rev Med 34: 161-168.
11. Ren J, Davidoff AJ (1997): Diabetes rapidly induces contractile dysfunctions in isolated ventricular myocytes. Am J Physiol 41: H148-H158.
12. Schaffer SW (1991): Cardiomyopathy associated with non-insulin-dependent diabetes. Mol Cell Biochem 107: 1-20.
13. Schaffer SW, Allo S, Punna S, White T (1991): Defective response to cAMP-dependent protein kinase in non-insulin-dependent diabetic heart. Am J Physiol 261: E369-E376.
14. Schaffer SW, Mozaffari MS, Artman M, Wilson GL (1989): Basis for myocardial mechanical defects associated with non-insulin-dependent diabetes. Am J Physiol 256: E25-E30.
15. Schaffer SW, Tan BH, Wilson GL (1985): Development of a cardiomyopathy in a model of non-insulin-dependent diabetes. Am J Physiol 248: H179-H185.
16. Schaffer SW, Wilson GL (1993): Insulin resistance and mechanical dysfunction in hearts of Wistar rats with streptozotocin-induced non-insulin-dependent diabetes mellitus. Diabetologia 36: 195-199.
17. Weir GC, Clore ET, Zmachinski CJ, Bonner-Weir S (1981): Islet secretion in a new experimental model for non-insulin-dependent diabetes. Diabetes 30: 590-595.
18. Yu Z, Tibbits GF, McNeill JH (1994): Cellular functions of diabetic cardiomyocytes: contractility, rapid-cooling contracture, and ryanodine binding. Am J Physiol 266: H2082-H2089.