A rare cause of syncope in a patient with diabetes mellitus - A case report

Annals of the Academy of Medicine Singapore

Volumn 30, Issue 4, 2001, Pages 436-439

  Tavintharan, S ^b   Mukherjee, J J ^a  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^b NONE

Author keywords

Diabetes mellitus; Endogenous hyperinsulinaemia; Hypoglycaemia; Insulinoma

Indexed keywords

ARTICLE; CASE REPORT; HUMAN; HYPOGLYCEMIA; INSULINOMA; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS TUMOR; SYNCOPE;

DIABETES MELLITUS, TYPE 2; HUMANS; HYPOGLYCEMIA; INSULINOMA; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; SYNCOPE;

EID: 0035406444     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Towler D A, Havlin C E, Craft S, Cryer P. Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms. Diabetes 1993; 42:1791-8.
2. Roith D L. Tumor-induced hypoglycemia. N Engl J Med 1999; 341: 757-8.
3. Service F J. Hypoglycemic disorders. N Engl J Med 1995; 332:1144-5.
4. Koch C A, Rother K I, Roth J. Tumour hypoglycemia linked to IGF-II. In: Rosenfeld R, Roberts C T, editors. Contemporary Endocrinology: The IGF-II System. Totowa NJ: Humana Press, 1999:675-98.
5. Vinik A I, Thompson N W, Averbuch S D. Neoplasms of the gastroenteropancreatic endocrine system. In: Holland J F, Frei III, Bast R C, Kufe D W, Morton D L, Weichselbaum R R, editors. Cancer Medicine. Philadelphia: Lea and Feiberger, 1993; XXVI-5:1180-209.
6. Stefanini P, Carboni M, Patrassi N. Surgical treatment and prognosis of insulinoma. Clin Gastroenterol 1984; 3:697-709.
7. Service F J, McMahon M M, O'Brein P C, Ballard D J. Functioning insulinoma - incidence, recurrence, and long-term survival of patients. Mayo Clinic Proc 1991; 66:711-9.
8. Cryer P E, Polonski K S. Glucose homeostasis and hypoglycemia: management of insulinoma. In: Wilson J D, Foster D W, Kronenberg H M, Larsen P R, editors. Williams Textbook of Endocrinology. Philadelphia: WB Saunders, 1992:1241.
9. UKPDS Group. Intensive blood-glucose control with sulphonylurea or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352:837-53.
10. Perry R R, Vinik A I. Diagnosis and management of functioning islet cell tumours. J Clin Endocrinol Metab 1995; 80:2273-8.
11. Norton J A, Whitman E D. Insulinoma. Endocrinologist 1995; 3: 258-67.
12. Marks V, Samols E. Insulinoma: natural history and diagnosis. Clin Gastroenterol 1974; 3:559-73.
13. Priestly J T. Hyperinsulinism. Ann R Coll Surg Engl 1962; 31:211-27.
14. Kane L A, Grant C S, Nippoldt T B, Service F J. Insulinoma in a patient with NIDDM. Diabetes Care 1993; 16:1298-300.
15. Svatberg J, Stridsberg M, Wilander E, Andersson D E, Eriksson B. Tumour-induced hypoglycaemia in a patient with insulin-dependent diabetes mellitus. J Intern Med 1996; 239:181-5.
16. Fajans S S, Floyd J C. Fasting hypoglycaemia in adults. N Engl J Med 1976; 294:766-72.
17. Service F J, Dale A J, Elveback L R, Jiang N S. Insulinoma: clinical and diagnostic features of 60 consecutive cases. Mayo Clin Proc 1976; 51:417-29.
18. Clark L R, Jaffe M H, Choyke P L, Grant E G, Zeman R K. Pancreatic imaging. Radiol Clin North Am 1985; 23:489-501.
19. Fraker D L, Norton J A. Localization and resection of insulinomas and gastrinomas. JAMA 1988; 259:3601-5.
20. Norton J A, Shawker T H, Doppman J H, Fraker D L, Cromack D T, Gorden P, et al. Localization and surgical treatment of occult insulinomas. Ann Surg 1990; 212:615-20.
21. Zimmer T, Stolzel U, Bader M, Koppenhagen K, Hamm B, Buhr H, et al. Endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localization of insulinomas and gastrinomas. Gut 1996; 39:562-8.
22. Sandler R, Horwitz D L, Rubenstein A H, Kuzuya H. Hypoglycemia and endogenous hyperinsulinism complicating diabetes mellitus. Application of the C-peptide assay to diagnosis and therapy. Am J Med 1975; 59:730-6.