The Effects of Overnight Fasting, Feeding, or Sucrose Supplementation Prior to Necropsy in Rats

Contemporary Topics in Laboratory Animal Science

Volumn 40, Issue 4, 2001, Pages 36-40

  Turner, Patricia V ^a   Albassam, Mudher A ^a   Walker, Robin M ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN; SUCROSE;

ANIMAL; ANIMAL DISEASE; ARTICLE; AUTOPSY; DIET RESTRICTION; EATING; FEMALE; LIVER; MALE; METABOLISM; PATHOLOGY; RAT; TOXICITY TESTING; WISTAR RAT;

ANIMALS; AUTOPSY; EATING; FASTING; FEMALE; GLYCOGEN; LIVER; MALE; RATS; RATS, WISTAR; SUCROSE; TOXICITY TESTS;

EID: 0035405831     PISSN: 10600558     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Levine, S., and A. Saltzman. 1998. An alternative to overnight withholding of food from rats. Contemp. Top. Lab. Anim. Sci. 37:59-61.
2. Gottschall, E. G., and D. B. McMillan. 1985. Structural changes in rat hepatocytes following ingestion of sugar solutions. Acta Anat. 123:178-188.
3. Snedecor, G. W. and W. G. Cochran. 1967. Statistical method, 6th edition. Iowa State University Press, Ames, Iowa.
4. Hausner, E. A., K. L. Schlingmann, H. W. Chen, et al. 1995. Hepatic and adrenal changes in rabbits associated with hyperlipidemia caused by a semi-synthetic diet. Lab. Anim. Sci. 45:663-670.
5. Levine, S., and A. Saltzman. 2000. Feeding sugar overnight maintains metabolic homeostasis in rats and is preferable to overnight starvation. Lab. Anim. 34:301-306.
6. Hoffmann, W. E., J. Kramer, A. R. Main, et al. 1989. Clinical enzymology, p. 239-242. In W. F. Loeb and F. W. Quimby (ed.), The clinical chemistry of laboratory animals. Pergammon Press, Inc., Exeter, England.
7. Pagliassotti, M. J., P. A. Prach, T. A. Koppenhafer, et al. 1996. Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats. Am. J. Physiol. 271:R1319-R1326.
8. Horton, T. J., E. C. Gayles, P. A. Prach, et al. 1997. Female rats do not develop sucrose-induced insulin resistance. Am. J. Physiol. 272:R1571-R1576.
9. Beverly, J. L., Z. -J. Yang, M. Kosecki, et al. 1997. Meal-induced changes in hepatic glycogen of fasted rats. Physiol. Behav. 62:1093-1098.
10. Jeffrey, P., M. Burrows, and A. Bye. 1987. Does the rat have an empty stomach after an overnight fast? Lab. Anim. 21:330-334.
11. De Boer, S. F., S. J. Koopmans, J. L. Slangen, et al. 1989. Effects of fasting on plasma catecholamine, corticosterone and glucose concentrations under basal and stress conditions in individual rats. Physiol. Behav. 45:989-994.