Synthesis of C-5′-alkyl substituted 17-spirofuran 19-norsteroids

Steroids

Volumn 66, Issue 7, 2001, Pages 569-579

  Khripach, Vladimir A ^a   Zhabinskii, Vladimir N ^a   Tsavlovskii, Dmitrii N ^a   Drachenova, Olga A ^a   Ivanova, Galina V ^a   Konstantinova, Olga V ^a   Zavadskaya, Margarita I ^a   Lyakhov, Alexander S ^a   Govorova, Alla A ^a   Groen, Marinus B ^b   De Groot, Aede ^c  

^a INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

^b NV ORGANON   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

1,3 Dipolar cycloaddition; 19 Norsteroids; Acetylenic alcohols; Nitrile oxides; Spirofurans

Indexed keywords

ALCOHOL DERIVATIVE; FURAN DERIVATIVE; GESTAGEN; NORSTEROID;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS;

ANIMALS; FURANS; HUMANS; NORSTEROIDS; PROGESTERONE; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035400884     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(00)00222-1     Document Type: Article

References (14)

1. Synthesis and X-ray analysis of (20S)-22-benzamido-6β-methoxy-3α,5-cyclo-26,27-bisnorcholest-22-en-24-one
2. Synthesis of steroidal 23-enamino-25-ketones-potential intermediates for preparation of vitamins D and analogs
3. A nitrile oxide approach to the construction of the side chain of metabolites and analogs of vitamin D, functionalized at C-23
4. 17β-Hydroxy-17α-isoxazolyl steroids
5. Stereoselective synthesis of 20-(hydrofuryl)steroids via isoxasole derivatives