Trans- and cis-DNA adduct concentration in epidermis from mouse and rat skin treated ex vivo with benzo[a]pyrene diol epoxide and its corresponding chlorohydrin

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 478, Issue 1-2, 2001, Pages 199-206

  Vock, Esther H ^a,b   Wolfe, Alan R ^a   Meehan, Thomas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Benzo a pyrene; DNA binding; PAH chlorohydrin; Skin; Stereochemistry

Indexed keywords

7,8,9 TRIHYDROXY 10 CHLORO 7,8,9,10 TETRAHYDROBENZO[A]PYRENE; 7,8,9,10 TETRAHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; ALPHA CHLOROHYDRIN; BENZO[A]PYRENE DERIVATIVE; DEOXYADENOSINE; DEOXYGUANOSINE; DIHYDROXYBENZO[A]PYRENE OXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DNA ADDUCT; DOSE RESPONSE; EPIDERMIS; ESSENTIAL HYPERTENSION; HYPERTENSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOISOMERISM;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; BENZOPYRENES; DEOXYADENOSINES; DEOXYGUANOSINE; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMIS; MALE; MICE; MICE, INBRED C57BL; MUTAGENS; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; SKIN; STEREOISOMERISM;

ANIMALIA; RODENTIA;

EID: 0035400485     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00153-1     Document Type: Article

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