Unusual diversity in α-amanitin sensitivity of RNA polymerases in trichomonads

Molecular and Biochemical Parasitology

Volumn 115, Issue 2, 2001, Pages 239-247

  Vaáčová, Štěpánka ^a   Tachezy, Jan ^a   Ullu, Elisabetta ^b   Tschudi, Christian ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

amanitin; Gene transcription; Permeable cells; Tagetitoxin; Trichomonas vaginalis; Tritrichomonas foetus

Indexed keywords

ALPHA AMANITIN; BETA TUBULIN; DACTINOMYCIN; DNA DIRECTED RNA POLYMERASE III; LYSOPHOSPHATIDYLCHOLINE; MALATE DEHYDROGENASE (DECARBOXYLATING); RIBOSOME RNA; RNA POLYMERASE II; TAGETITOXIN; TOXIN; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; RNA SYNTHESIS; RNA TRANSCRIPTION; SPECIES DIFFERENTIATION; TRICHOMONAS FOETUS; TRICHOMONAS VAGINALIS;

AMANITINS; ANIMALS; CELL MEMBRANE PERMEABILITY; DICARBOXYLIC ACIDS; ENZYME INHIBITORS; LYSOPHOSPHATIDYLCHOLINES; ORGANOPHOSPHORUS COMPOUNDS; RNA POLYMERASE II; RNA, PROTOZOAN; TRANSCRIPTION, GENETIC; TRICHOMONADIDA; TRICHOMONAS VAGINALIS; TRITRICHOMONAS FOETUS;

EID: 0035400291     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00294-8     Document Type: Article

References (41)

1. Specific inhibition of nuclear RNA polymerase II by α-amanitin
2. Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from the posterior silk gland of Bombyx mori
3. Studies on the inhibition by alpha-amanitin of single-step addition reactions and productive RNA synthesis catalysed by wheat-germ RNA polymerase II
4. In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin
5. RNA polymerase I-mediated protein-coding gene expression in Trypanosoma brucei
6. Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes
7. Alpha-amanitin resistant transcription of protein coding genes in insect and bloodstream form Trypanosoma brucei
8. An enlarged largest subunit of Plasmodium falciparum RNA polymerase II defines conserved and variable RNA polymerase domains
9. Chromatographic separation of DNA dependent RNA polymerases and molecular properties of RNA polymerase II from a Leishmania spp
10. Characterisation of the RNA polymerases of Crithidia fasciculata
11. DNA-dependent RNA polymerases from Acanthamoeba castellanii: Properties and levels of activity during encystment
12. RNA polymerase I can mediate expression of CAT and neo protein-coding genes in Trypanosoma brucei
13. Transcription of protein-coding genes in trypanosomes by RNA polymerse I
14. Transcription in the early diverging eukaryote Trichomonas vaginalis: An unusual RNA polymerase II and α-amanitin-resistant transcription of protein-coding genes
15. Transcriptional analysis of the glutamate dehydrogenase gene in the primitive eukaryote, Giardia lamblia. Identification of a primordial gene promoter
16. Transcription of protein-coding genes in Entamoeba histolytica is sensitive to high concentrations of α-amanitin
17. Zinc deficiency and the Euglena gracilis chromatin: Formation of an alpha-amanitin-resistant RNA polymerase II
18. Permeable trypanosome cells as a model system for transcription and trans-splicing
19. Employment of experimental animals in studies of Trichomonas vaginalis infection
20. Tritrichomonas foetus: Iron acquisition from lactoferrin and transferrin
21. Tritrichomonas mobilensis n. sp. (Zoomastigophorea: Trichomonadida) from the Bolivian squirrel monkey Saimiri boliviensis boliviensis
22. Studies on pathogenicity of Tetratrichomonas gallinarum in mice and turkey poults
23. The establishment of various trichomonads of animals and man in axenic cultures
24. Rapid isolation of eukaryotic DNA
25. Rapid and practical DNA isolation from Trichomonas vaginalis and other nuclease-rich protozoa
26. Transcription in yeast: Alpha-amanitin sensitivity and other properties which distinguish between RNA polymerases I and III
27. Unique amanitin resistance of RNA synthesis in isolated nuclei from Amanita species accumulating amanitins
28. An α-amanitin-resistant DNA-dependent RNA polymerase II from the fungus Aspergilus nidulans
29. A DNA-dependent RNA synthesis by wheat-germ RNA polymerase II insensitive to the fungal toxin alpha-amanitin
30. Clustered alpha-amanitin resistance mutations in mouse
31. Myogenic differentiation of L6 rat myoblasts: Evidence for pleiotropic effects on myogenesis by RNA polymerase II mutations to alpha-amanitin resistance
32. Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes
33. Mutant Caenorhabditis elegans RNA polymerase II with a 20 000-fold reduced sensitivity to alpha-amanitin
34. Amitochondriate amoebae and the evolution of DNA-dependent RNA polymerase II
35. Cytologie ultrastructurale, systematique et evolution des Trichomonadida
36. Evolutionary and systematic relationships in the flagellate order Trichomonadida Kirby
37. Phylogeny of trichomonads based on partial sequences of large subunit rRNA and on cladistic analysis of morphological data
38. Molecular phylogeny of parabasalids based on small subunit rRNA sequences, with emphasis on the Trichomonadinae subfamily
39. Phylogenetic relationships of the glycolytic enzyme, glyceraldehyde-3-phosphate dehydrogenase, from parabasalid flagellates
40. Phylogenetic implication of iron-containing superoxid dismutase genes from trichomonad species
41. Molecular evolution inferred from small subunit rRNA sequences: What does it tell us about phylogenetic relationships and taxonomy of the parabasalids?