Conformational stability and warfarin-binding properties of human serum albumin studied by recombinant mutants

Biochemical Journal

Volumn 357, Issue 1, 2001, Pages 269-274

  Watanabe, H ^a   Kragh Hansen, U ^a   Tanase, S ^a   Nakajou, K ^a   Mitarai, M ^a   Iwao, Y ^a   Maruyama, T ^a   Otagiri, M ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Conformational changes; High affinity binding; Protein stability; Site directed mutagenesis; Thermal denaturation

Indexed keywords

BINDING ENERGY; CONFORMATIONS; FLUORESCENCE; MUTAGENESIS; PH EFFECTS; PHYSIOLOGY; PROTEINS; THERMAL EFFECTS; YEAST;

MUTANTS;

BIOCHEMISTRY;

SERUM ALBUMIN; WARFARIN;

ARTICLE; BACTERIUM MUTANT; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; ENZYME STABILITY; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS; WARFARIN;

BACTERIA (MICROORGANISMS);

EID: 0035397254     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3570269     Document Type: Article

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