Stability and compatibility of tirofiban hydrochloride during simulated Y-site administration with other drugs

American Journal of Health-System Pharmacy

Volumn 58, Issue 13, 2001, Pages 1218-1223

  Bergquist, P A ^a   Manas, D ^a   Hunke, W A ^a   Reed, R A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Anxiolytics; Dextrose; Diazepam; Diluents; Incompatibilities; Injections; Platelet aggregation inhibitors; Precipitation; Sedatives and hypnotics; Sodium chloride; Stability; Storage; Tirofiban hydrochloride

Indexed keywords

ADRENALIN; ATROPINE; DIAZEPAM; DOBUTAMINE; FUROSEMIDE; GLUCOSE; GLYCERYL TRINITRATE; MIDAZOLAM; MORPHINE SULFATE; PROPRANOLOL; SODIUM CHLORIDE; TIROFIBAN;

ARTICLE; DRUG MIXTURE; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL;

EID: 0035395597     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/58.13.1218     Document Type: Article

References (12)

1. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction
2. Stability of tirofiban hydrochloride in three commonly used i.v. solutions and polyvinyl chloride administration sets
3. Evaluation of the stability of furosemide in intravenous infusions by reversed phase HPLC
4. Assay for epinephrine and its impurities using reversed phase HPLC
5. Photochemical decomposition of midazolam IV. Study of pH-dependent stability by HPLC
6. Development and validation of LC methods for the quantitation of propranolol, metoprolol, atenolol, and bisoprolol: Application in solution stability studies
7. Solubility principles and practices for parenteral drug dosage form development