Some computational aspects of the kindling model for neuropsychiatric disorders

Neurocomputing

Volumn 38-40, Issue , 2001, Pages 1297-1306

  Huber, Martin Tobias ^a   Braun, Hans Albert ^a   Voigt, Karlheinz ^a   Krieg, Jürgen Christian ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Affective disorders; Computational model; Episode sensitization; Kindling; Nonlinear dynamics

Indexed keywords

COMPUTATIONAL METHODS; COMPUTER SIMULATION; DISEASES; HUMAN ENGINEERING;

BIOLOGICAL CHANGES;

NEUROLOGY;

ARTICLE; BEHAVIOR; CHAOTIC DYNAMICS; CONTROLLED STUDY; FEEDBACK SYSTEM; KINDLING; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MENTAL DISEASE; MOOD DISORDER; NEUROLOGIC DISEASE; NONLINEAR SYSTEM; POSITIVE FEEDBACK; PRIORITY JOURNAL; SEIZURE; SENSITIZATION; SIMULATION;

EID: 0035383945     PISSN: 09252312     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-2312(01)00489-1     Document Type: Article

References (17)

1. G.L. Baker, J.P. Gollub, Chaotic Dynamics: An Introduction, Cambridge University Press, Cambridge, 1990.
2. S.N. Ghaemi, E. Eboiman, F.K. Goodwin, Kindling and secondmessengers: an approach to the neurobiology of recurrence in bipolar disorder, Biol. Psychiatry 45 (1999) 137-144.
3. A. Gottschalk, M.S. Bauer, P.S. Whybrow, Evidence of chaotic mood variation in bipolar disorder, Arch. Gen. Psychiatry 52 (1995) 947-959.
4. M.T. Huber, J.C. Krieg, M. Dewald, K. Voigt, H.A. Braun, Stimulus sensitivity and neuromodulatory properties of noisy intrinsic neuronal oscillators, Biosystems 48 (1998) 95-104.
5. M.T. Huber, H.A. Braun, K. Voigt, J.C. Krieg, Computational properties of intrinsic subthreshold oscillations: possible implications for function and dysfunction, in: J. Bower (Ed.), Computational Neuroscience: Trends in Research 1998, Plenum Press, New York, 1998, pp. 197-202.
6. M.T. Huber, H.A. Braun, J.C. Krieg, Consequences of deterministic and random dynamics for the course of affective disorders, Biol. Psychiatry 46 (1999) 256-262.
7. M.T. Huber, H.A. Braun, J.C. Krieg, Effects of noise on different disease states of recurrent affective disorders, Biol. Psychiatry 47 (2000) 634-642.
8. M.T. Huber, H.A. Braun, J.C. Krieg, Noise, nonlinear dynamics the timecourse of affective disorders, Chaos, Solitons Fractals 11 (2000) 1923-1928.
9. E. Kraepelin, Manic-Depressive Insanity and Paranoia (Translated by R.M. Barclay), G.M. Robertson (Ed.), E.&S. Livingstone, Edinburgh, 1921, pp. 179-181.
10. K.G. Kramlinger, R.M. Post, Ultra-rapid and ultradian cycling in bipolar affective illness, Br. J. Psychiatry 168 (1996) 314-323.
11. G. LeMasson, E. Marder, L.F. Abbott, Activity-dependent regulation of conductances in model neurons, Science 259 (1992) 1915-1917.
12. A.J. Mandell, S. Knapp, C. Ehlers, P.V. Russo, The stability of constrained randomness: lithium prophylaxis at several neurobiological levels, in: B.M. Post, J. Ballenger (Eds.), Neurobiology of Mood Disorders, Williams and Wilkins, Baltimore, 1985, pp. 744-776.
13. M.V. Mascagni, Numerical methods for neuronal modelling, in: C. Koch, I. Segev (Eds.), Methods in Neuronal Modelling, The MIT Press, Cambridge, MA and London, England, 1987, pp. 439-481.
14. R.M. Post, Transduction of psychological stress into the neurobiology of recurrent affective disorder, Am. J. Psychiatry 149 (1992) 999-1010.
15. R.M. Post, S.R.B. Weiss, The neurobiology of treatment-resistant mood disorders, in: F.E. Bloom, D.J. Kupfer (Eds.), Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, 1995, pp. 1155-1170.
16. R.M. Post, S.R.B. Weiss, Sensitization and kindling phenomena in mood, anxiety, and obsessive-compulsive disorders: the role of serotonergic mechanisms in illness progression, Biol. Psychiatry 44 (1998) 193-206.
17. S.H. Strogatz, Nonlinear Dynamics and Chaos, Addison-Wesley, Reading, MA, 1994.