High performance liquid chromatographic analysis of a new proton pump inhibitor KR60436 and its active metabolite O-demethyl-KR60436 in rat plasma samples using column-switching

Archives of Pharmacal Research

Volumn 24, Issue 3, 2001, Pages 207-210

  Lee, Hyun Mee ^a   Lee, Hee Yong ^a   Choi, Joong Kwon ^b   Lee, Hye Suk ^a  

^a Wonkwang University   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Column switching; HPLC; KR60436; O demethyl KR60436; Rat plasma

Indexed keywords

1 (2 METHYL 4 METHOXYPHENYL) 4 ((2 HYDROXYETHYL)AMINO) 6 TRIFLUOROMETHOXY 2,3 DIHYDROPYRROLO(3,2 C)QUINOLINE; 1-(2-METHYL-4-METHOXYPHENYL)-4-((2-HYDROXYETHYL)AMINO)-6-TRIFLUOROMETHOXY-2,3-DIHYDROPYRROLO(3,2-C)QUINOLINE; ENZYME INHIBITOR; PROTON PUMP; PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE;

ANIMAL; ARTICLE; BLOOD; DEALKYLATION; DRUG ANTAGONISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; RAT; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEALKYLATION; ENZYME INHIBITORS; MALE; PROTON PUMPS; PYRROLES; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0035376444     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02978258     Document Type: Article

References (6)

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