Acute promyelocytic leukemia: The study of t(15;17) translocation by fluorescent in situ hybridization, reverse transcriptase-polymerase chain reaction and cytogenetic techniques

Brazilian Journal of Medical and Biological Research

Volumn 34, Issue 6, 2001, Pages 735-743

  Chauffaille, M L L F ^a   Figueiredo, M S ^a   Beltrani, R ^a   Antunes, S V ^a   Yamamoto, M ^a   Kerbauy, J ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

FISH; Karyotype; PML RARA gene rearrangement; R; T PCR

Indexed keywords

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ARTICLE; CHILD; CHROMOSOME 15; CHROMOSOME 17; COMPARATIVE STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETIC PROCEDURES; GENETICS; HUMAN; KARYOTYPING; MALE; METHODOLOGY; MIDDLE AGED; MINIMAL RESIDUAL DISEASE; PROMYELOCYTIC LEUKEMIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; CHILD; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 17; ELECTROPHORESIS, AGAR GEL; FEMALE; GENE REARRANGEMENT; GENETIC TECHNIQUES; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; MIDDLE AGED; NEOPLASM, RESIDUAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSLOCATION, GENETIC;

EID: 0035374601     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2001000600006     Document Type: Article

References (27)

1. Rowley JD, Golomb HM & Dougherty C (1977). 15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia. Lancet, 1: 549-550.
2. Biondi A, Rambaldi A, Alcalay M, Pandolfi PP, LoCoco F, Diverio D, Rossi V, Mercarelli A, Longo L & Zanguilli D (1991). RARA gene rearrangement as a genetic marker for diagnosis and monitoring in APL. Blood, 77: 1418-1422.
3. Allford S, Grimwade D. Langarbeer S, Duprez E, Saurin A, Chatters S, Walker H, Roberts P, Rogers J, Bain B, Patterson K, McKernan A, Freemont P, Solomon E, Burnett A, Goldstone A & Linch D (1999). Identification of the t(15;17) in AML FAB types other than M3: evaluation of the role of molecular screening for the PML/ RARA rearrangement in newly diagnosed AML. British Journal of Haematology, 105: 198-207.
4. LoCoco F, Diverio D, Falini B, Biondi A, Nervi C & Policci PG (1999). Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia. Blood, 94: 12-22.
5. Diverio D, Rossi V, Avvisati G, de Santis S, Pistilli A, Pane F, Saglio G, Martinelli G, Petti MC, Santoro A, Pelicci PG, Mandelli F, Biondi A & LoCoco FL (1998). Early detection of relapse by prospective RT-PCR analysis of the PML/RARalpha fusion gene in patients with APL enrolled n the GIMEMA AIEOP multicenter AIDA trial. Blood, 92: 784-789.
6. Willman CL (1999). Molecular evaluation of acute myeloid leukemia. Seminars in Hematology, 36: 390-400.
7. Huang ME, Ye YC, Chen SR, Chai JR, Lu JX, Zhoa L, Gu LJ & Wang ZY (1988). Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood, 72: 567-572.
8. Kanamaru A, Takemoto Y, Tanimoto M, Murakami H, Asou N, Kobayashi T, Kuriyama K, Ohmoto E, Sakamaki H, Tsubari K, Hiraoka A, Yamada O, Oh H, Saito K, Matsuda S, Minato K, Ueda T & Ohno O (1995). All trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia. Japan Adult Study Group. Blood, 85: 1202-1206.
9. Jansen JH, Ridder MC, Geertsma WMC, Erpelinck CAJ, van Lom K, Smit EME, Slater R, Reijden BA, Greef GE, Sonneveld P & Lowenberg B (1999). Complete remission of t(11;17) positive acute promyelocytic leukemia induced by all trans retinoic acid and granulocyte colony stimulating factor Blood, 94: 39-45.
10. Fenaux P, Chastang C, Chevret S, Sanz M, Dombret H, Archimbaud E, Fey M, Rayon C, Huguet F, Sotto JJ, Gardin C, Makhoul PC, Travade P, Solary E, Fegueux N, Bordessoule D, Miguel JS, Link H, Desablens B, Stamatoullas A, Deconick E, Maloisel F, Castaigne S, Preudhomme C & Degos L (1999). A randomized comparison of all trans retinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed APL Blood, 94: 1192-1200.
11. Schad CR, Hanson CA, Paietta E, Caasper J, Jalal SM & Dewald GW (1994). Efficacy of fluorescent in situ hybridization for detecting PML/RARA gene fusion in treated and untreated acute promyelocytic leukemia. Mayo Clinic Proceedings, 69: 1047-1053.
12. Fukutani H, Naoe T, Ohno R, Yoshida H, Kiyoi H, Miyawaki S, Morishita H, Sano F, Kamibayashi H & Matsue K (1995). Prognostic significance of the RT-PCR assay of PML-RARA transcripts in acute promyelocytic leukemia. Leukemia, 9: 588-593.
13. Warrell RP, Barret AJ, Pandolfi PP & Willman CL (1997). Acute myelocytic leukemia. 1999 Education Program, American Society of Hematology, 120-137.
14. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DAG, Gralnick HR & Sultan C (1976). Proposals for the classification of the acute leukemias. FrenchAmerican-British (FAB) co-operative group British Journal of Haematology, 33: 451-458.
15. Mittelman F (1995). International System for Human Cytogenetics Nomenclature (ISCN-An). S. Karger, Basel.
16. Chomczynski P & Sacchi N (1987). Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Annals of Biochemistry, 162: 156-159.
17. Castaigne S, Balitrand N, de The H, Dejean A, Degos L & Chomienne C (1992). A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia. Blood, 79: 3110-3115.
18. Warrell RP, de The H, Wang ZY & Degos L (1993). Acute promyelocytic leukemia. New England Journal of Medicine, 329: 177-189.
19. Fenaux P, Castaigne S, Dombret H, Archimbaud E, Duarte M, Morel P, Lamy T, Tilly H, Guerci A & Maloisel F (1992). Alltransretinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia. A pilot study on 26 cases. Blood, 80: 2176-2181.
20. Mancini M, Nanni M, Cedrone M, Diverio D, Awisati G, Riccioni R, DeCuia MR, Fenu S & Alimena G (1995). Combined cytogenetic, FISH and molecular analysis in acute promyelocytic leukemia at diagnosis and in complete remission. British Journal of Haematology, 91: 878-884.
21. Burnett AK, Grimwade D, Solomon E, Wheatley K & Goldstone AH (1999). Presenting white blood cell count and kinetics of molecular remission predict prognosis in APL treated with all-trans retinoic acid: result of the randomized MRC trial. Blood, 93: 4131-4143.
22. Zelent A (1998) PCR cloning of N termi-nal RAR isoforms and APL associated PLZF-RAR alpha fusion proteins. Methods in Molecular Biology, 89: 307-332.
23. Wells RA, Hummel JL, De Koven A, Zipursky A, Kirby M, Dube I & Kamel-Reid S (1996). A new variant translocation in acute promyelocytic leukemia: molecular characterization and clinical correlation. Leukemia, 10: 735-740.
24. Berger R, Bernheim A, Daniel MT, Valensi F & Flandrin G (1983). Cytological types of mitosis and chromosome abnormalities in acute leukemia. Leukemia Research, 7: 221-236.
25. Tashiro S, Tanaka K, Asou H, Kyo T, Dohy H, Sukuri K & Kamada N (1993). Detection of PML/RARA rearrangements by PCR using genomic DNA in patients with APL. Japanese Journal of Cancer Research, 84: 110-113.
26. Vahdat L, Maslak P, Miller WH, Eardley A, Heller G, Scheinberg DA & Warrell RP (1994). Early mortality and the retinoic acid syndrome in acute promyelocytic leukemia: impact of leukocytosis, low-dose chemotherapy, PML/RAR-alpha isoform and CD 13 expression in patients treated with ATRA Blood, 84: 3843-3849.
27. Fukutami H, Naoe T, Ohno R, Yoshida H, Miyawaki S, Shimazaki C, Miyake T, Nakayama Y, Kobayashi H & Goto S (1995). Isoforms of PML-retinoic acid receptor alpha fused transcripts affect neither clinical features of acute promyelocytic leukemia nor prognosis after treatment with all-trans retinoic acid. The Leukemia Study Group of the Ministry of Health and Welfare (Kosheisho) (1995). Leukemia, 9: 1478-1482.