Delayed re-endothelialization and T-cell infiltration following intracoronary radiation therapy in the porcine model

International Journal of Radiation Oncology Biology Physics

Volumn 50, Issue 2, 2001, Pages 495-501

  Kollum, Marc ^a   Cottin, Yves ^a   Chan, Rosanna C ^a   Kim, Han Soo ^a   Bhargava, Balram ^a   Vodovotz, Yoram ^a   Waksman, Ron ^a  

^a WASHINGTON HOSPITAL CENTER   (United States)

Author keywords

Angioplasty; Brachytherapy; Leukocytes; Macrophages; Restenosis

Indexed keywords

CELLS; IMAGE ANALYSIS; RADIOTHERAPY;

T-CELL INFILTRATION;

ONCOLOGY;

ALPHA ACTIN; CD3 ANTIGEN;

ADVENTITIA; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BALLOON CATHETER; CELL DENSITY; CELL INFILTRATION; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM; GAMMA IRRADIATION; HISTOLOGY; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; INTIMA; INTRACORONARY RADIATION; MACROPHAGE; MORPHOMETRICS; NICK END LABELING; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; RADIOTHERAPY; RESTENOSIS; SMOOTH MUSCLE FIBER; SWINE; T LYMPHOCYTE;

ACTINS; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANIMALS; ANTIGENS, CD3; APOPTOSIS; BRACHYTHERAPY; CELL COUNT; CORONARY VESSELS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; IN SITU NICK-END LABELING; IRIDIUM RADIOISOTOPES; MACROPHAGES; MUSCLE, SMOOTH, VASCULAR; SWINE; T-LYMPHOCYTES; TUNICA INTIMA;

EID: 0035370310     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(01)01497-3     Document Type: Article

References (42)

1. Dangas G., Fuster V. Management of restenosis after coronary intervention. Am Heart J. 132:1996;428-436.
2. Massullo V., Teirstein P.S., Jani S., et al. Endovascular brachytherapy to inhibit coronary artery restenosis An introduction to the SCRIPPS Coronary Radiation to Inhibit Proliferation Post Stenting trial . Int J Radiat Oncol Biol Phys. 36:1996;973-975.
3. Teirstein P.S., Massullo V., Jani S., et al. Catheter-based radiotherapy to inhibit restenosis after coronary stenting. N Engl J Med. 336:1997;1697-1703.
4. Teirstein P.S., Massullo V., Jani S., et al. Two-year follow-up after catheter-based radiotherapy to inhibit coronary restenosis. Circulation. 99:1999;243-247.
5. Condado J.A., Waksman R., Gurdiel O., et al. Long-term angiographic, and clinical outcome after percutaneous transluminal coronary angioplasty, and intracoronary radiation therapy in humans. Circulation. 96:1997;727-732.
6. King SB3, Williams DO, Chougule P; et al. Endovascular beta-radiation to reduce restenosis after coronary balloon angioplasty: Results of the beta energy restenosis trial (BERT). Circulation 1998;97:2025-2030.
7. Waksman R. Endovascular beta radiation in the swine model. 2nd ed. 1998;Futura Publishing, Armonk, NY.
8. Waksman R. Local catheter-based intracoronary radiation therapy for restenosis. Am J Cardiol. 78:1996;23-28.
9. Newby A.C., George S.J. Proliferation, migration, matrix turnover, and death of smooth muscle cells in native coronary and vein graft atherosclerosis. Curr Opin Cardiol. 11:1996;574-582.
10. Bursch W., Oberhammer F., Schulte-Hermann R. Cell death by apoptosis and its protective role against disease. Trends Pharmacol Sci. 13:1992;245-251.
11. Crompton N.E. Programmed cellular response to ionizing radiation damage. Acta Oncol. 37:1998;129-142.
12. Gajdusek C.M., Tian H., London S., et al. Gamma radiation effect on vascular smooth muscle cells in culture. Int J Radiat Oncol Biol Phys. 36:1996;821-828.
13. Wilcox J.N., Waksman R., King S.B., et al. The role of the adventitia in the arterial response to angioplasty the effect of intravascular radiation . Int J Radiat Oncol Biol Phys. 36:1996;789-796.
14. Rubin P. Cellular and molecular mechanisms of radiation inhibition of restenosis. Part I: role of the macrophage and platelet-derived growth factor . Int J Radiat Oncol Biol Phys. 40:1998;929-941.
15. Libby P., Clinton S.K. Cytokines as mediators of vascular pathology. Nouv Rev Fr Hematol. 34:(Suppl.):1992;S47-S53.
16. Lee P.C., Gibbons G.H., Dzau V.J. Cellular and molecular mechanisms of coronary artery restenosis. Coron Artery Dis. 4:1993;254-259.
17. Schwartz S.M., Reidy M.A., O'Brien E.R.M. Assessment of factors important in atherosclerotic occlusion and restenosis. Thromb Haemost. 74:1995;541-551.
18. Delic J., Magdelenat H., Barbaroux C., et al. In vivo induction of apoptosis in human lymphocytes by therapeutic fractionated total body irradiation. Br J Radiol. 68:1995;997-1003.
19. Waksman R., Robinson K.A., Crocker I.R., et al. Endovascular low-dose irradiation inhibits neointima formation after coronary artery balloon injury in swine. A possible role for radiation therapy in restenosis prevention. Circulation. 91:1995;1533-1539.
20. Nath R., Amols H., Coffey C., et al. Intravascular brachytherapy physics Report of the AAPM Radiation Therapy Committee Task Group no. 60. American Association of Physicists in Medicine (In Process Citation) . Med Phys. 26:1999;119-152.
21. Bhoopat L., Turner R.R., Stathopoulos E., et al. Immunohistochemical characterization of two new monoclonal antibodies (LN-4, LN-5) reactive with human macrophage subsets and derived malignancies in B5-fixed, paraffin-embedded tissues. Blood. 71:1988;1079-1085.
22. Wilcox J.N., Waksman R., King S.B., et al. Role of the adventitia in the arterial response to angioplasty. 1996;Nucletron BV, Veenendaal, The Netherlands.
23. Bhargava B., Vodovotz Y., Waksman R. Intracoronary radiation therapy for prevention of restenosis. Indian Heart J. 50:(Suppl. I):1998;120-129.
24. Diamond D.A., Vesely T.M. The role of radiation therapy in the management of vascular restenosis. Part I. Biologic basis. J Vasc Interv Radiol. 9:1998;199-208.
25. Teirstein P.S. Prevention of vascular restenosis with radiation. Tex Heart Inst J. 25:1998;30-33.
26. Vodovotz Y, Waksman R. Potential roles for nitric oxide and transforming growth factor-1 in endovascular brachytherapy. 2nd ed. Armonk, NY: Futura; 1999. p. 139-146.
27. Bochaton-Piallat M.L., Gabbiani F., Redard M., et al. Apoptosis participates in cellularity regulation during rat aortic intimal thickening. Am J Pathol. 146:1995;1059-1064.
28. Han D.K., Haudenschild C.C., Hong M.K., et al. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Pathol. 147:1995;267-277.
29. Kollum M., Kaiser S., Kinscherf R., et al. Apoptosis after stent implantation compared with balloon angioplasty in rabbits. Role of macrophages. Arterioscler Thromb Vasc Biol. 17:1997;2383-2388.
30. Malik N., Francis S.E., Holt C.M., et al. Apoptosis and cell proliferation after porcine coronary angioplasty. Circulation. 98:1998;1657-1665.
31. Rogers C., Edelman E.R., Simon D.I. A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits. Proc Natl Acad Sci U S A. 95:1998;10134-10139.
32. Stewart J.R., Fajardo L.F., Gillette S.M., et al. Radiation injury to the heart. Int J Radiat Oncol Biol Phys. 31:1995;1205-1211.
33. 32P-emitting stent placement. Circulation 1998;98:I-779-I-779.
34. Vodovotz Y., Bhargava B., Collins S.D., et al. Intracoronary radiation increases thrombosis rate with decreased luminal thrombi and thrombus area. J Am Coll Cardiol. 33:(Suppl. A):1999;300A.
35. Blum A., Vardinon N., Kaplan G., et al. Autoimmune and inflammatory responses may have an additive effect in postpercutaneous transluminal coronary angioplasty restenosis. Am J Cardiol. 81:1998;339-341.
36. Detre K., Holubkov R., Kelsey S., et al. One-year follow-up results of the-1986 National Heart, Lung, and Blood Institute's Percutaneous Transluminal Coronary Angioplasty Registry. Circulation. 80:1989;421-428.
37. Wilensky R.L., March K.L., Gradus-Pizlo I., et al. Vascular injury, repair, and restenosis after percutaneous transluminal angioplasty in the atherosclerotic rabbit. Circulation. 92:1995;2995-3005.
38. Falk E. Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes. Am J Cardiol. 63:1989;114E-120E.
39. Savill J. Apoptosis in disease. Eur J Clin Invest. 24:1994;715-723.
40. Schwartz L.M., Smith S.W., Jones M.E., et al. Do all programmed cell deaths occur via apoptosis? Proc Natl Acad Sci U S A. 90:1993;980-984.
41. Gold R., Schmied M., Giegerich G., et al. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest. 71:1994;219-225.
42. Sanders E.J., Wride M.A. Ultrastructural identification of apoptotic nuclei using the TUNEL technique. Histochem J. 28:1996;275-281.