Beyond kinetic traps in RNA folding

Current Opinion in Structural Biology

Volumn 11, Issue 3, 2001, Pages 309-314

  Treiber, Daniel K ^a,b   Williamson, James R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Aventa Biosciences Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIVALENT CATION; RIBONUCLEASE P; RIBONUCLEOPROTEIN; RIBOZYME; RNA;

ESCHERICHIA COLI; EXON; INTRON; KINETICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REVIEW; RNA CONFORMATION; TETRAHYMENA;

ESCHERICHIA COLI; TETRAHYMENA;

EID: 0035366896     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(00)00206-2     Document Type: Review

References (44)

1. The complete atomic structure of the large ribosomal subunit at 2.4 angstrom resolution
2. Structure of functionally activated small ribosomal subunit at 3.3 angstrom resolution
3. Structure of the 30S ribosomal subunit
4. Exposing the kinetic traps in RNA folding
5. 2+ concentration for kinetic folding of the Tetrahymena ribozyme
6. Fast folding of a ribozyme by stabilizing core interactions: Evidence for multiple folding pathways in RNA
7. New pathways in folding of the Tetrahymena group I RNA enzyme
8. A single-molecule study of RNA catalysis and folding
9. RNA folding causes secondary structure rearrangement
10. Concerted kinetic folding of a multidomain ribozyme with a disrupted loop-receptor interaction
11. Conformational changes of transfer ribonucleic acid. Relaxation kinetics of the early melting transition of methionine transfer ribonucleic acid
12. Pathway modulation, circular permutation and rapid RNA folding under kinetic control
13. Magnesium-dependent folding of a self-splicing RNA: Exploring the link between cooperativity, thermodynamics, and kinetics
14. Folding intermediates of a self-splicing RNA: Mispairing of the catalytic core
15. Kinetic intermediates trapped by native interactions in RNA folding
16. The effect of long-range loop-loop interactions on folding of the Tetrahymena self-splicing RNA
17. RNA folding at millisecond intervals by synchrotron hydroxyl radical footprinting
18. Stability and cooperativity of individual tertiary contacts in RNA revealed through chemical denaturation
19. Intermediates and kinetic traps in the folding of a large ribozyme revealed by circular dichroism and UV absorbance spectroscopies and catalytic activity
20. Small angle X-ray scattering reveals a compact intermediate in RNA folding
21. Facilitation of group I splicing in vivo: Misfolding of the Tetrahymena IVS and the role of ribosomal exons
22. A magnesium ion core at the heart of a ribozyme domain
23. The P4-P6 domain directs higher order folding of the Tetrahymena ribozyme core
24. The kinetic folding pathway of the Tetrahymena ribozyme reveals possible similarities between RNA and protein folding
25. Assembly of a ribonucleoprotein catalyst by tertiary structure capture
26. Effects of polyvalent cations on the folding of an rRNA three-way junction and binding of ribosomal protein S15
27. Ligand-induced conformational changes observed in single RNA molecules
28. In vivo facilitation of Tetrahymena group I intron splicing in Escherichia coli pre-ribosomal RNA
29. Folding of a large ribozyme during transcription and the effect of the elongation factor NusA
30. The parallel universe of RNA folding
31. Escherichia coli proteins, including ribosomal protein S12, facilitate in vitro splicing of phage T4 intron by acting as RNA chaperones
32. Assaying RNA chaperone activity in vivo using a novel folding trap
33. A ribosomal function is necessary for efficient splicing of the T4 phage thymidylate synthase intron in vivo
34. 2+-dependent folding of a large ribozyme without kinetic traps
35. A collapsed non-native RNA folding state
36. Folding mechanism of the Tetrahymena ribozyme P4-P6 domain
37. An early transition state for folding of the P4-P6 RNA domain
38. phe and the catalytic domain of the B. subtilis P RNA determined by small-angle X-ray scattering
39. A collapsed state functions to self-chaperone RNA folding into a native ribonucleoprotein complex
40. From Levinthal pathways to funnels
41. Compact but disordered states of RNA
42. Structure of the S15, S6, S18-rRNA complex: Assembly of the 30S ribosome central domain
43. Studies of RNA cleavage by photolysis of N-hydroxypyridine-2(1H)-thione, a new photochemical footprinting method
44. Kinetic analysis of the M1 RNA folding pathway