Relationship of Regional Adiposity to Insulin Resistance in Nonobese Japanese Type 2 Diabetic Patients

Diabetes Care

Volumn 24, Issue 5, 2001, Pages 966-968

  Taniguchi, Ataru ^a   Nakai, Yoshikatsu ^b   Sakai, Masahiko ^a   Yoshii, Satoru ^a   Hayashi, Masaru ^a   Nishitani, Kazukiyo ^a   Hamanaka, Daizaburo ^a   Nakaishi, Shigeo ^a   Kamamoto, Takayuki ^a   Nagata, Itaru ^a   Okumura, Takahide ^a   Kishimoto, Hiroyuki ^a   Fukushima, Mitsuo ^b  

^a KANSAI DENRYOKU HOSPITAL   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATED HEMOGLOBIN; INSULIN;

ADIPOSE TISSUE; ADULT; AGED; ASIAN; BLOOD; BODY MASS; FEMALE; GLUCOSE BLOOD LEVEL; HISTOLOGY; HUMAN; INSULIN RESISTANCE; JAPAN; LETTER; MALE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN; VISCERA;

ADIPOSE TISSUE; ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; INSULIN RESISTANCE; JAPAN; MALE; MIDDLE AGED; SKIN; VISCERA;

EID: 0035345535     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.24.5.966     Document Type: Article

References (26)

1. DeFronzo RA: Lilly Lecture 1987: The triumvirate: β-cell, muscle, liver: a collusion responsible for NIDDM: Diabetes 37:667-687, 1988
2. Gerich JE: The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity. Endocrine Rev 19:491-503, 1998
3. Vague J: The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease. Am J Clin Nutr 4:20, 1956
4. Kissebah AH, Peiris AN: Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Diabetes Metab Rev 5:83-109, 1989
5. Kissebah A, Vydelingum N, Murray R, Evans D, Hartz A, Kalkhoff RK, Adams PW: Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 54:254-260, 1982
6. Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S: Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 36:54-59, 1987
7. Haffner SM, Stern MP, Hazuda HP, Pugh J, Patterson J: Do upper-body and centralized obesity measure different aspects of regional body-fat distribution? Relationship to non-insulin-dependent diabetes mellitus, lipids, and lipoproteins. Diabetes 36:43-51, 1987
8. Banerji MA, Chaiken RL, Gordon D, Kral JG, Lebovitz HE: Does intra-abdominal adipose tissue in black men determine whether NIDDM is insulin-resistant or insulin-sensitive? Dibetes 44:141-146, 1995
9. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Adams-Huet B, Grundy SM: Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM. Diabetes, 45:1684-1693, 1996
10. Taniguchi A, Nakai Y, Fukushima M, Kawamura H, Imura H, Nagata I, Tokuyama K: Pathogenic factors responsible for glucose tolerance in patients with NIDDM. Diabetes 41:1540-1546, 1992
11. Nagasaka S, Tokuyama K, Kusaka I, Hayashi H, Rokkaku K, Nakamura T, Kawakami A, Higashiyama M, Ishikawa S, Saito T: Endogenous glucose production and glucose effectiveness in type 2 diabetic subjects derived from stable-labeled minimal model approach. Diabetes 48: 1054-1060, 1999
12. Taniguchi A, Fukushima M, Sakai M, Nagata I, Doi K, Nagasaka S, Tokuyama K, Nakai Y: Insulin secretion, insulin sensitivity, and glucose effectiveness in nonobese individuals with varying degrees of glucose tolerance (Letter). Diabetes Care 23: 127-128, 2000
13. World Health Organization: Diabetes Mellitus: Report of a WHO Study Group. Geneva, World Health Org., 1985 (Tech. Rep. Ser., no. 727)
14. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-508, 1972
15. Matthews D, Hosker J, Rudenski A, Naylor B, Treacher D, Turner R: Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419, 1985
16. Groop LC: Drug treatment of non-insulin-dependent diabetes mellitus. In Textbook of Diabetes. Pickup J, Williams G, Eds. Oxford, U.K., Blackwell Science, 1997, p. 38.1-38.18
17. Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Targher G, Alberiche M, Bonadonna RC, Muggeo M: Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. Diabetes 47:1643-1649, 1998
18. Emoto M, Nishizawa Y, Maekawa K, Hiura Y, Kanda H, Kawagishi T, Shoji T, Okuno Y, Morii H: Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care 22:818-822, 1999
19. Bergstrom RW, Newell-Morris LL, Leonetti DL, Shuman WP, Wahl PW, Fujimoto WY: Association of elevated lasting C-peptide level and increased intra-abdominal fat distribution with development of NIDDM in Japanese-American men. Diabetes 39:104-111, 1990
20. Yoshizumi T, Nakamura T, Yamane M, Islam AH, Menju M, Yamasaki K, Arai T, Kotani K, Funahashi T, Yamashita S, Matsuzawa Y: Abdominal fat: standardized technique for measurement at CT. Radiology 211:283-286, 1999
21. Taniguchi A, Nakai Y, Doi K, Fukuzawa H, Fukushima M, Kawamura H, Tokuyama K, Suzuki M, Fujitani J, Tanaka H, Nagata I: Insulin sensitivity, insulin secretion, and glucose effectiveness in obese subjects: a minimal model analysis. Metabolism 44: 1397-1400, 1995
22. Taniguchi A, Fukushima M, Sakai M, Miwa K, Makita T, Nagasaka S, Doi K, Okumura T, Fukuda A, Kishimoto H, Fukuda T, Nakaishi S, Tokuyama K, Nakai Y: Remnant-like particle cholesterol, triglycerides, and insulin resistance in nonobese Japanese type 2 diabetic patients. Diabetes Care 23:1766-1769, 2000
23. Taniguchi A, Fukushima M, Sakai M, Kataoka K, Nigata I, Doi K, Arakawa H, Nagasaka S, Tokuyama K, Nakai Y: The role of the body mass index and triglyceride levels in identifying insulin-sensitive and insulin-resistant variants in Japanese non-insulin-dependent diabetic patients. Metabolism 49:1001-1005, 2000
24. Taniguchi A, Fukushima M, Sakai M, Kataoka K, Miwa K, Nagata I, Doi K, Tokuyama K, Nakai Y: Insulin-sensitive and insulin-resistant variants in nonobese Japanese type 2 diabetic patients: the role of triglycerides in insulin resistance. (Letter). Diabetes Care 22:2100-2101, 1999
25. Fukushima M, Taniguchi A, Sakai M, Doi K, Nagata I, Nagasaka S, Tokuyama K, Nakai Y: Effect of bezafibrate on insulin sensitivity in nonobese Japanese type 2 diabetic patients (Letter). Diabetes Care 23:259, 2000
26. Taniguchi A, Fukushima M, Sakai M, Nagasaka S, Doi K, Nagata I, Matsushita K, Ooyama Y, Kawamoto A, Nakasone M, Tokuyama K, Nakai Y: Effect of physical training on insulin sensitivity in Japanese type 2 diabetic patients: role of serum triglyceride levels (Letter). Diabetes Care 23: 857-858, 2000