Occurrence of paradoxical or sustained control by an enzyme when overexpressed: Necessary conditions and experimental evidence with regard to hepatic glucokinase

Biochemical Journal

Volumn 355, Issue 3, 2001, Pages 787-793

  De Atauri, Pedro ^a   Acerenza, Luis ^b   Kholodenko, Boris N ^c   De La Iglesia, Núria ^a   Guinovart, Joan J ^a   Agius, Loranne ^d   Cascante, Marta ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Allosteric enzymes; Co operativity; Glucokinase; Metabolic control; Regulatory protein

Indexed keywords

BIOCHEMISTRY; ELASTICITY; PROTEINS; SUBSTRATES;

PARADOXICAL CONTROL;

ENZYMES;

GLUCOKINASE; GLYCOGEN; LIVER ENZYME; REGULATOR PROTEIN;

ARTICLE; ENZYME KINETICS; GLYCOGEN METABOLISM; GLYCOGEN SYNTHESIS; LIVER CELL; LIVER METABOLISM; MATHEMATICAL ANALYSIS; MATHEMATICAL PARAMETERS; METABOLIC REGULATION; PRIORITY JOURNAL;

EID: 0035340023     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3550787     Document Type: Article

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