-
1
-
-
0032960181
-
Cancer epigenetics comes of age
-
P. A. Jones and P. W. Laird (1999). Cancer epigenetics comes of age. Nat. Gene. 21:163-167.
-
(1999)
Nat. Gene
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
2
-
-
0031029853
-
Expression genetics in cancer: Shifting the focus from DNA to RNA
-
R. Sager (1997). Expression genetics in cancer: Shifting the focus from DNA to RNA. Proc. Natl. Acad. Sci. U.S.A. 94:952-955.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 952-955
-
-
Sager, R.1
-
3
-
-
0034305821
-
DNA methylation in health and disease
-
K. D. Robertson and A.P. Wolffe (2000). DNA methylation in health and disease. Nat. Rev. 1:11-19.
-
(2000)
Nat. Rev.
, vol.1
, pp. 11-19
-
-
Robertson, K.D.1
Wolffe, A.P.2
-
4
-
-
0031566065
-
A genomic element within the third intron of the human oxytocin receptor gene may be involved in transcriptional suppression
-
Y. Mizumoto, T. Kimura, and R. Ivell (1997). A genomic element within the third intron of the human oxytocin receptor gene may be involved in transcriptional suppression. Mol Cell Endocrinol. 135: 29-138.
-
(1997)
Mol. Cell Endocrinol.
, vol.135
, pp. 129-138
-
-
Mizumoto, Y.1
Kimura, T.2
Ivell, R.3
-
5
-
-
0030700454
-
Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation
-
R. Wicki, C. Franz, F. A. Scholl, C. W. Heizmann, and B. W. Schafr (1997). Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation. Cell Calcium 22:243-254.
-
(1997)
Cell Calcium
, vol.22
, pp. 243-254
-
-
Wicki, R.1
Franz, C.2
Scholl, F.A.3
Heizmann, C.W.4
Schafr, B.W.5
-
6
-
-
0030710153
-
How does DNA methylation repress transcription?
-
S. U. Kass, D. Pruss, and A. P. Wolffe (1997). How does DNA methylation repress transcription? Trends Genet 13:444-449.
-
(1997)
Trends Genet.
, vol.13
, pp. 444-449
-
-
Kass, S.U.1
Pruss, D.2
Wolffe, A.P.3
-
7
-
-
0031899814
-
Inactivation of p16 in human mammary epithelial cells by CpG island methylation
-
S. A. Foster, D. J. Wong, M. T. Barrett, and D. A. Galloway (1998). Inactivation of p16 in human mammary epithelial cells by CpG island methylation. Mol. Cell Biol. 18:1793-1801.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1793-1801
-
-
Foster, S.A.1
Wong, D.J.2
Barrett, M.T.3
Galloway, D.A.4
-
8
-
-
0032080669
-
Mechanisms of inactivation of E-cadherin in breast cancer cell lines
-
S. Hiraguri, T. Godfrey, H. Nakamura, J. Graff, C. Collins, L. Shayesteh, N. Doggett, K. Johnson, M. Wheelock, J. Herman, S. Baylin, D. Pinkel, and J. Gray (1998). Mechanisms of inactivation of E-cadherin in breast cancer cell lines. Cancer Res. 58:1972-1977.
-
(1998)
Cancer Res.
, vol.58
, pp. 1972-1977
-
-
Hiraguri, S.1
Godfrey, T.2
Nakamura, H.3
Graff, J.4
Collins, C.5
Shayesteh, L.6
Doggett, N.7
Johnson, K.8
Wheelock, M.9
Herman, J.10
Baylin, S.11
Pinkel, D.12
Gray, J.13
-
9
-
-
0030843274
-
Methylation of the BRCA1 gene in sporadic breast cancer
-
A. Dobrovic and D. Simpfendorfer (1997). Methylation of the BRCA1 gene in sporadic breast cancer. Cancer Res. 57:3347-3350.
-
(1997)
Cancer Res.
, vol.57
, pp. 3347-3350
-
-
Dobrovic, A.1
Simpfendorfer, D.2
-
10
-
-
0033863507
-
Corepressor complexes and remodeling chromatin for repression
-
A. P. Wolffe, F. D. Urnov, and D. Guschin (2000). Corepressor complexes and remodeling chromatin for repression. Biochem. Soc. Trans. 28:379-386.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 379-386
-
-
Wolffe, A.P.1
Urnov, F.D.2
Guschin, D.3
-
11
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
[see comments]
-
X. Nan, H. H. Ng, C. A. Johnson, C. D. Laherty, B. M. Turner, R. N. Eisenman, and A. Bird (1998). Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex [see comments]. Nature393:386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
12
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
E. Cameron, K. Bachman, S. Myohanen, J. Herman, and S. Baylin (1999). Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat. Genet. 21: 03-107.
-
(1999)
Nat. Genet.
, vol.21
, pp. 103-107
-
-
Cameron, E.1
Bachman, K.2
Myohanen, S.3
Herman, J.4
Baylin, S.5
-
13
-
-
0027183088
-
The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression
-
P. Jeppesen and B. M. Turner (1993). The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell 74:281-289.
-
(1993)
Cell
, vol.74
, pp. 281-289
-
-
Jeppesen, P.1
Turner, B.M.2
-
15
-
-
0033813699
-
Linker histone binding and displacement: Versatile mechanism for transcriptional regulation
-
J. Zlatanova, P. Caiafa, and K. Van Holde (2000). Linker histone binding and displacement: Versatile mechanism for transcriptional regulation. FASEB J. 14:1697-1704.
-
(2000)
FASEB J.
, vol.14
, pp. 1697-1704
-
-
Zlatanova, J.1
Caiafa, P.2
Van Holde, K.3
-
16
-
-
0034730745
-
Ubiquitin-activating/conjugating activity of TAF(II)250, a mediator of activation of gene expression in Drosophila
-
A. D. Pham and F. Sauer (2000). Ubiquitin-activating/conjugating activity of TAF(II)250, a mediator of activation of gene expression in Drosophila. Science 289:2357-2360.
-
(2000)
Science
, vol.289
, pp. 2357-2360
-
-
Pham, A.D.1
Sauer, F.2
-
17
-
-
0034695456
-
Rad6-dependent ubiquitination of histone H2B in yeast
-
K. Robzyk, J. Recht, and M. A. Osley (2000). Rad6-dependent ubiquitination of histone H2B in yeast. Science 287:501-504.
-
(2000)
Science
, vol.287
, pp. 501-504
-
-
Robzyk, K.1
Recht, J.2
Osley, M.A.3
-
18
-
-
0033861664
-
Co-operation between protein-acetylating and protein-methylating co-activators in transcriptional activation
-
M. R. Stallcup, D. Chen, S. S. Koh, H. Ma, Y. Lee, H. Li, B. T. Schurter, and D. W. Aswad (2000). Co-operation between protein-acetylating and protein-methylating co-activators in transcriptional activation. Biochem. Soc. Trans. 28:415-418.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 415-418
-
-
Stallcup, M.R.1
Chen, D.2
Koh, S.S.3
Ma, H.4
Lee, Y.5
Li, H.6
Schurter, B.T.7
Aswad, D.W.8
-
19
-
-
0029693220
-
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation
-
C. VanLint, S. Emiliani, and E. Verdin (1996). The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Exp. 5:245-253.
-
(1996)
Gene Exp.
, vol.5
, pp. 245-253
-
-
VanLint, C.1
Emiliani, S.2
Verdin, E.3
-
20
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
-
M. Frommer, L. E. McDonald, D. S. Millar, C. M. Collis, F. Watt, G. W. Grigg, P. L. Molloy, and C. L. Paul (1992). A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. U.S.A. 89: 827-1831.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
Collis, C.M.4
Watt, F.5
Grigg, G.W.6
Molloy, P.L.7
Paul, C.L.8
-
21
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
J. G. Herman, A. Merlo, L. Mao, R. G. Lapidus, J-P. J. Issa, N. E. Davidson, D. Sidransky, and S. B. Baylin (1995). Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 55: 525-4530.
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.-P.J.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
22
-
-
0023663398
-
DNA methylation pattern and restriction endonuclease accessibility in chromatin of a germ-line specific gene, the rainbow trout protamine gene
-
G. P. Delcuve and J. R. Davie (1987). DNA methylation pattern and restriction endonuclease accessibility in chromatin of a germ-line specific gene, the rainbow trout protamine gene. Nucleic Acids Res. 15:3385-3396.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 3385-3396
-
-
Delcuve, G.P.1
Davie, J.R.2
-
23
-
-
0004270170
-
-
(Eds.), John Wiley Inc., New York
-
F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (Eds.), Current Protocols in Molecular Biology John Wiley Inc., New York.
-
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
24
-
-
0029953722
-
Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern
-
M. Braunstein, R. E. Sobel, C. D. Allis, B. M. Turner, and J. R. Broach (1996). Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol. Cell Biol. 16:4349-4356.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 4349-4356
-
-
Braunstein, M.1
Sobel, R.E.2
Allis, C.D.3
Turner, B.M.4
Broach, J.R.5
-
25
-
-
0030451463
-
Reduced levels of histone h3 acetylation on the inactive X chromosome in human females
-
B. A. Boggs, B. Connors, R. E. Sobel, A. C. Chinault, and C. D. Allis (1996). Reduced levels of histone h3 acetylation on the inactive X chromosome in human females. Chromosoma 105(5):303-309.
-
(1996)
Chromosoma
, vol.105
, Issue.5
, pp. 303-309
-
-
Boggs, B.A.1
Connors, B.2
Sobel, R.E.3
Chinault, A.C.4
Allis, C.D.5
-
26
-
-
0033397841
-
Preparation of site-specific antibodies to acetylated histones
-
D. A. White, N. D. Belyaev, and B. M. Turner (1999). Preparation of site-specific antibodies to acetylated histones. Methods (Duluth). 19(3):417-424.
-
(1999)
Methods (Duluth)
, vol.19
, Issue.3
, pp. 417-424
-
-
White, D.A.1
Belyaev, N.D.2
Turner, B.M.3
-
27
-
-
0033388858
-
In vivo cross-linking and immunoprecipitation for studying dynamic protein: DNA associations in chromatin environment
-
M. H. Kuo and C. D. Allis (1999). In vivo cross-linking and immunoprecipitation for studying dynamic protein: DNA associations in chromatin environment. Methods (Duluth). 19(3):425-433.
-
(1999)
Methods (Duluth)
, vol.19
, Issue.3
, pp. 425-433
-
-
Kuo, M.H.1
Allis, C.D.2
-
28
-
-
0034697973
-
BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer
-
D. A. Bochar, L. Wang, H. Beniya, A. Kinev, Y. Xue, W. S. Lane, W. Wang, F. Kashanchi, and R. Shiekhattar (2000). BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer. Cell 102:257-265.
-
(2000)
Cell
, vol.102
, pp. 257-265
-
-
Bochar, D.A.1
Wang, L.2
Beniya, H.3
Kinev, A.4
Xue, Y.5
Lane, W.S.6
Wang, W.7
Kashanchi, F.8
Shiekhattar, R.9
-
29
-
-
0033636595
-
Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation
-
P. Cheung, K. G. Tanner, W. L. Cheung, P. Sassone-Corsi, J. M. Denu, and C. D. Allis (2000). Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol. Cell. 5:905-915.
-
(2000)
Mol. Cell.
, vol.5
, pp. 905-915
-
-
Cheung, P.1
Tanner, K.G.2
Cheung, W.L.3
Sassone-Corsi, P.4
Denu, J.M.5
Allis, C.D.6
-
30
-
-
0034679625
-
Phosphoacetylation of histone H3 on c-fos- and c- jun-associated nucleosomes upon gene activation
-
A. L. Clayton, S. Rose, M. J. Barratt, and L. C. Mahadevan (2000). Phosphoacetylation of histone H3 on c-fos- and c- jun associated nucleosomes upon gene activation. EMBO J. 19: 714-3726.
-
(2000)
EMBO J.
, vol.19
, pp. 3714-3726
-
-
Clayton, A.L.1
Rose, S.2
Barratt, M.J.3
Mahadevan, L.C.4
-
31
-
-
0033382686
-
BRCA1 and BRCA2 and breast cancer incidence: A review
-
D. T. Bishop (1999). BRCA1 and BRCA2 and breast cancer incidence: A review. Ann. Oncol. 10:113-119.
-
(1999)
Ann. Oncol.
, vol.10
, pp. 113-119
-
-
Bishop, D.T.1
-
32
-
-
0033832393
-
Hereditary breast cancer: A review
-
B. Arver, Q. Du, J. Chen, L. Luo, and A. Lindblom (2000). Hereditary breast cancer: A review. Semin Cancer Biol. 10:271-288.
-
(2000)
Semin. Cancer Biol.
, vol.10
, pp. 271-288
-
-
Arver, B.1
Du, Q.2
Chen, J.3
Luo, L.4
Lindblom, A.5
-
33
-
-
0028950999
-
Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
-
M. E. Thompson, R. A. Jensen, P. S. Obermiller, D. L. Page, and J. T. Holt (1995). Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat. Genet. 9:444-450.
-
(1995)
Nat. Genet.
, vol.9
, pp. 444-450
-
-
Thompson, M.E.1
Jensen, R.A.2
Obermiller, P.S.3
Page, D.L.4
Holt, J.T.5
-
34
-
-
0032953384
-
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas
-
C. A. Wilson, L. Ramos, M. R. Villasenor, K. H. Anders, M. F. Press, K. Clarke, B. Karlan, J. J. Chen, R. Scully, D. Livingston, R. H. Zuch, M. H. Kanter, S. Cohen, F. J. Calzone, and D. J. Slamon (1999). Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas. Nat Genet. 21:236-240.
-
(1999)
Nat. Genet.
, vol.21
, pp. 236-240
-
-
Wilson, C.A.1
Ramos, L.2
Villasenor, M.R.3
Anders, K.H.4
Press, M.F.5
Clarke, K.6
Karlan, B.7
Chen, J.J.8
Scully, R.9
Livingston, D.10
Zuch, R.H.11
Kanter, M.H.12
Cohen, S.13
Calzone, F.J.14
Slamon, D.J.15
-
35
-
-
0033869528
-
Regional methylation of the 5′ end CpG island of BRCA1 is associated with reduced gene expression in human somatic cells
-
F. Magdinier, L. M. Billard, G. Wittmann, L. Frappart, M. Benchaib, G. M. Lenoir, J. F. Guerin, and R. Dante (2000). Regional methylation of the 5′ end CpG island of BRCA1 is associated with reduced gene expression in human somatic cells. FASEB J. 14:1585-1594.
-
(2000)
FASEB J.
, vol.14
, pp. 1585-1594
-
-
Magdinier, F.1
Billard, L.M.2
Wittmann, G.3
Frappart, L.4
Benchaib, M.5
Lenoir, G.M.6
Guerin, J.F.7
Dante, R.8
-
36
-
-
0034284118
-
Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter
-
J. C. Rice and B. W. Futscher (2000). Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter. Nucleic Acids Res. 28:3233-3239.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3233-3239
-
-
Rice, J.C.1
Futscher, B.W.2
-
37
-
-
0032497635
-
Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells
-
J. C. Rice, K. S. Massey-Brown, and B. W. Futscher (1998). Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells. Oncogene 17: 807-1812.
-
(1998)
Oncogene
, vol.17
, pp. 1807-1812
-
-
Rice, J.C.1
Massey-Brown, K.S.2
Futscher, B.W.3
-
38
-
-
0033857349
-
Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens
-
J. C. Rice, H. Ozcelik, P. Maxeiner, I. Andrulis, and B. W. Futscher (2000). Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens. Carcinogenesis 21:1761-1765.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1761-1765
-
-
Rice, J.C.1
Ozcelik, H.2
Maxeiner, P.3
Andrulis, I.4
Futscher, B.W.5
-
39
-
-
0033970096
-
Tumor-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer
-
T. Bianco, G. Chenevix-Trench, D. C. Walsh, J. E. Cooper, and A. Dobrovic (2000). Tumor-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer. Carcinogenesis 21:147-151.
-
(2000)
Carcinogenesis
, vol.21
, pp. 147-151
-
-
Bianco, T.1
Chenevix-Trench, G.2
Walsh, D.C.3
Cooper, J.E.4
Dobrovic, A.5
-
40
-
-
2642611983
-
Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers
-
H. Ozcelik, M. D. To, J. Couture, S. B. Bull, and I. L. Andrulis (1998). Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers. Int. J. Cancer 77:1-6.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 1-6
-
-
Ozcelik, H.1
To, M.D.2
Couture, J.3
Bull, S.B.4
Andrulis, I.L.5
-
41
-
-
0030761231
-
Complexregulation of the BRCA1 gene
-
C. F. Xu, J. A. Chambers, and E. Solomon (1997). Complexregulation of the BRCA1 gene. J. Biol. Chem. 272:20994-20997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20994-20997
-
-
Xu, C.F.1
Chambers, J.A.2
Solomon, E.3
-
42
-
-
0033605681
-
Positive regulation of the BRCA1 promoter
-
S. Thakur C. M. Croce (1999). Positive regulation of the BRCA1 promoter. J. Biol. Chem. 274:8837-8843.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8837-8843
-
-
Thakur, S.1
Croce, C.M.2
-
43
-
-
0033581874
-
The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells
-
V. Budhram-Mahadeo, D. Ndisang, T. Ward, B. L. Weber, and D. S. Latchman (1999). The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells. Oncogene 18:6684-6691.
-
(1999)
Oncogene
, vol.18
, pp. 6684-6691
-
-
Budhram-Mahadeo, V.1
Ndisang, D.2
Ward, T.3
Weber, B.L.4
Latchman, D.S.5
-
44
-
-
0032935739
-
POU family transcription factors in the nervous system
-
D. S. Latchman (1999). POU family transcription factors in the nervous system. J. Cell Physiol. 179:126-133.
-
(1999)
J. Cell Physiol.
, vol.179
, pp. 126-133
-
-
Latchman, D.S.1
-
45
-
-
0033865957
-
Roles of BRCA1 and its interacting proteins
-
C. X. Deng and S. G. Brodie (2000). Roles of BRCA1 and its interacting proteins. Bioessays 22:728-737.
-
(2000)
Bioessays
, vol.22
, pp. 728-737
-
-
Deng, C.X.1
Brodie, S.G.2
-
46
-
-
0033967218
-
CBP/p300 interact with and function as transcriptional coactivators of BRCA1
-
G. M. Pao, R. Janknecht, H. Ruffner, T. Hunter, and I. M. Verma (2000). CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc. Natl. Acad. Sci. U.S.A. 97:1020-1025.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 1020-1025
-
-
Pao, G.M.1
Janknecht, R.2
Ruffner, H.3
Hunter, T.4
Verma, I.M.5
-
47
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Y. Wang, D. Cortez, P. Yazdi, N. Neff, S. J. Elledge, and J. Qin (2000). BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14:927-939.
-
(2000)
Genes Dev.
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
48
-
-
0033994345
-
Allelic loss at the BRCA1, BRCA2, and TP53 loci in human sporadic breast carcinoma
-
A. Katsama, G. Sourvinos, G. Zachos, and D. A. Spandidos (2000). Allelic loss at the BRCA1, BRCA2, and TP53 loci in human sporadic breast carcinoma. Cancer Lett. 150:165-170.
-
(2000)
Cancer Lett.
, vol.150
, pp. 165-170
-
-
Katsama, A.1
Sourvinos, G.2
Zachos, G.3
Spandidos, D.A.4
-
49
-
-
0033851695
-
Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines
-
C. Rauh-Adelmann, K. M. Lau, N. Sabeti, J. P. Long, S. C. Mok, and S. M. Ho (2000). Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines. Mol. Carcinog. 28: 36-246.
-
(2000)
Mol. Carcinog.
, vol.28
, pp. 236-246
-
-
Rauh-Adelmann, C.1
Lau, K.M.2
Sabeti, N.3
Long, J.P.4
Mok, S.C.5
Ho, S.M.6
-
50
-
-
0032580358
-
The BRCA2 is a histone acetyltransferase (HAT)
-
H. Siddique, J-P. Zou, V. N. Rao, and E. S. P. Reddy (1998). The BRCA2 is a histone acetyltransferase (HAT). Oncogene 16:2283-2285.
-
(1998)
Oncogene
, vol.16
, pp. 2283-2285
-
-
Siddique, H.1
Zou, J.-P.2
Rao, V.N.3
Reddy, E.S.P.4
-
51
-
-
0032512067
-
BRCA2 associates with acetyltransferase activity when bound to P/CAF
-
F. Fuks, J. Milner, and T. Kouzarides (1998). BRCA2 associates with acetyltransferase activity when bound to P/CAF. Oncogene 17: 531-2534.
-
(1998)
Oncogene
, vol.17
, pp. 2531-2534
-
-
Fuks, F.1
Milner, J.2
Kouzarides, T.3
-
52
-
-
0034077361
-
Genetic and epigenetic alterations in carcinogenesis
-
T. Sugimura and T. Ushijima (2000). Genetic and epigenetic alterations in carcinogenesis. Mutat. Res. 462:235-246.
-
(2000)
Mutat. Res.
, vol.462
, pp. 235-246
-
-
Sugimura, T.1
Ushijima, T.2
-
54
-
-
0033857729
-
Steroid receptor co-activators and the remodeling of chromatin
-
I. McEwan (2000). Steroid receptor co-activators and the remodeling of chromatin. Biochem. Soci. Trans. 28:369-373.
-
(2000)
Biochem. Soci. Trans.
, vol.28
, pp. 369-373
-
-
McEwan, I.1
-
55
-
-
0033857730
-
Transcriptional repression by nuclear receptors: Mechanisms and role in disease
-
J. D. Love, J. T. Gooch, L. Nagy, V. K. Chatterjee, and J. W. Schwabe (2000). Transcriptional repression by nuclear receptors: Mechanisms and role in disease. Biochem. Soc. Trans. 28:390-396.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 390-396
-
-
Love, J.D.1
Gooch, J.T.2
Nagy, L.3
Chatterjee, V.K.4
Schwabe, J.W.5
-
57
-
-
0032980308
-
The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer
-
J. Tsihlias, L. Kapusta, and J. Slingerland (1999). The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. Ann. Rev. Med. 50:401-423.
-
(1999)
Ann. Rev. Med.
, vol.50
, pp. 401-423
-
-
Tsihlias, J.1
Kapusta, L.2
Slingerland, J.3
-
58
-
-
0029967152
-
Silencing of p16/cdkn2 expression in human gliomas by methylation and chromatin condensation
-
J. F. Costello, M. S. Berger, H. J. S. Huang, and W. K. Cavenee (1996). Silencing of p16/cdkn2 expression in human gliomas by methylation and chromatin condensation. Cancer Res. 56(10):2405-2410.
-
(1996)
Cancer Res.
, vol.56
, Issue.10
, pp. 2405-2410
-
-
Costello, J.F.1
Berger, M.S.2
Huang, H.J.S.3
Cavenee, W.K.4
-
63
-
-
0033520944
-
Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
-
L. C. Sambucetti, D. D. Fischer, S. Zabludoff, P. O. Kwon, H. Chamberlin, N. Trogani, H. Xu, and D. Cohen (1999). Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J. Biol. Chem. 274:34940-34947.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34940-34947
-
-
Sambucetti, L.C.1
Fischer, D.D.2
Zabludoff, S.3
Kwon, P.O.4
Chamberlin, H.5
Trogani, N.6
Xu, H.7
Cohen, D.8
-
64
-
-
0033562343
-
waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells
-
waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells. J. Cell. Biochem. 73: 91-302.
-
(1999)
J. Cell. Biochem.
, vol.73
, pp. 291-302
-
-
Xiao, H.1
Hasegawa, T.2
Isobe, K.3
-
66
-
-
0028243879
-
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
-
T. C. Wang, R. D. Cardiff, L. Zukerberg, E. Lees, A. Arnold, and E. V. Schmidt (1994). Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369:669-671.
-
(1994)
Nature
, vol.369
, pp. 669-671
-
-
Wang, T.C.1
Cardiff, R.D.2
Zukerberg, L.3
Lees, E.4
Arnold, A.5
Schmidt, E.V.6
-
67
-
-
0028960821
-
Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer
-
C. Dickson, V. Fantl, C. Gillett, S. Brookes, J. Bartek, R. Smith, C. Fisher, D. Barnes, and G. Peters (1995). Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer. Cancer Lett. 90:43-50.
-
(1995)
Cancer Lett.
, vol.90
, pp. 43-50
-
-
Dickson, C.1
Fantl, V.2
Gillett, C.3
Brookes, S.4
Bartek, J.5
Smith, R.6
Fisher, C.7
Barnes, D.8
Peters, G.9
-
68
-
-
0030569556
-
Direct inhibition of the expression of cyclin D1 gene by sodium butyrate
-
F. Lallemand, D. Courilleau, M. Sabbah, G. Redeuilh, and J. Mester (1996). Direct inhibition of the expression of cyclin D1 gene by sodium butyrate. Biochem. Biophys. Res. Comm. 229:163-169.
-
(1996)
Biochem. Biophys. Res. Comm.
, vol.229
, pp. 163-169
-
-
Lallemand, F.1
Courilleau, D.2
Sabbah, M.3
Redeuilh, G.4
Mester, J.5
-
69
-
-
0032997146
-
Immunohistological analysis of E-cadherin, α-, β-, γ-catenin expression in colorectal cancer: Implications for cell adhesion and signaling
-
B. M. Ghadimi, J. Behrens, I. Hoffmann, W. Haensch, W. Birchmeier, and P. M. Schlag (1999). Immunohistological analysis of E-cadherin, α-, β-, γ-catenin expression in colorectal cancer: Implications for cell adhesion and signaling. Eur. J. Cancer 35:60-65.
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 60-65
-
-
Ghadimi, B.M.1
Behrens, J.2
Hoffmann, I.3
Haensch, W.4
Birchmeier, W.5
Schlag, P.M.6
-
70
-
-
1842301719
-
Expression of E-cadherin and catenins in invasive mammary carcinomas
-
W. Zschiesche, I. Schonborn, J. Behrens, K. Herrenknecht, F. Hartveit, P. Lilleng, and W. Birchmeier (1997). Expression of E-cadherin and catenins in invasive mammary carcinomas. Anticancer Res. 17:561-567.
-
(1997)
Anticancer Res.
, vol.17
, pp. 561-567
-
-
Zschiesche, W.1
Schonborn, I.2
Behrens, J.3
Herrenknecht, K.4
Hartveit, F.5
Lilleng, P.6
Birchmeier, W.7
-
71
-
-
0033853424
-
The E-cadherin-catenin complex in tumor metastasis. Structure, function and regulation
-
I. R. Beavon (2000). The E-cadherin-catenin complex in tumor metastasis. Structure, function and regulation. Eur. J. Cancer 36:1607-1620.
-
(2000)
Eur. J. Cancer
, vol.36
, pp. 1607-1620
-
-
Beavon, I.R.1
-
72
-
-
0028849277
-
E-Cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas
-
J. R. Graff, J. G. Herman, R. G. Lapidus, H. Chopra, R. Xu, D. F. Jarrard, W. B. Isaacs, P. M. Pitha, N. E. Davidson, and S. B. Baylin (1995). E-Cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res. 55: 195-5199.
-
(1995)
Cancer Res.
, vol.55
, pp. 5195-5199
-
-
Graff, J.R.1
Herman, J.G.2
Lapidus, R.G.3
Chopra, H.4
Xu, R.5
Jarrard, D.F.6
Isaacs, W.B.7
Pitha, P.M.8
Davidson, N.E.9
Baylin, S.B.10
-
73
-
-
0034662645
-
Aberrant methylation of the estrogen receptor and E-cadherin 5′ CpG islands increases with malignant progression in human breast cancer
-
S. J. Nass, J. G. Herman, E. Gabrielson, P. W. Iversen, F. F. Parl, N. E. Davidson, and J. R. Graff (2000). Aberrant methylation of the estrogen receptor and E-cadherin 5′ CpG islands increases with malignant progression in human breast cancer. Cancer Res. 60: 346-4348.
-
(2000)
Cancer Res.
, vol.60
, pp. 4346-4348
-
-
Nass, S.J.1
Herman, J.G.2
Gabrielson, E.3
Iversen, P.W.4
Parl, F.F.5
Davidson, N.E.6
Graff, J.R.7
-
74
-
-
0034723255
-
Methylation patterns of the E-cadherin 5′ CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression
-
J. R. Graff, E. Gabrielson, H. Fujii, S. B. Baylin, and J. G. Herman (2000). Methylation patterns of the E-cadherin 5′ CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J. Biol. Chem. 275: 727-2732.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2727-2732
-
-
Graff, J.R.1
Gabrielson, E.2
Fujii, H.3
Baylin, S.B.4
Herman, J.G.5
-
75
-
-
0021637178
-
The cytoskeleton in cancer cells
-
A. Ben-Ze'ev (1985). The cytoskeleton in cancer cells. Biochim. Biophys. Acta. 780:197-212.
-
(1985)
Biochim. Biophys. Acta
, vol.780
, pp. 197-212
-
-
Ben-Ze'ev, A.1
-
76
-
-
0028899770
-
Medical aspects of the actin cytoskeleton
-
P. A. Janmey and C. Chaponnier (1995). Medical aspects of the actin cytoskeleton. Curr. Opin. Cell Biol. 7:111-117.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 111-117
-
-
Janmey, P.A.1
Chaponnier, C.2
-
77
-
-
0033564171
-
Downregulated gelsolin expression in hyperplastic and neoplastic lesions of the prostate
-
H. K. Lee, D. Driscoll, H. Asch, B. Asch, and P. J. Zhang (1999). Downregulated gelsolin expression in hyperplastic and neoplastic lesions of the prostate. Prostate 40:14-19.
-
(1999)
Prostate
, vol.40
, pp. 14-19
-
-
Lee, H.K.1
Driscoll, D.2
Asch, H.3
Asch, B.4
Zhang, P.J.5
-
78
-
-
0029854630
-
Widespread loss of gelsolin in breast cancers of humans, mice, and rats
-
H. L. Asch, K. Head, Y. Dong, F. Natoli, J. S. Winston, J. S. Connolly, and B. B. Asch (1996). Widespread loss of gelsolin in breast cancers of humans, mice, and rats. Cancer Res. 56:4841-4845.
-
(1996)
Cancer Res.
, vol.56
, pp. 4841-4845
-
-
Asch, H.L.1
Head, K.2
Dong, Y.3
Natoli, F.4
Winston, J.S.5
Connolly, J.S.6
Asch, B.B.7
-
79
-
-
0028022785
-
Trichostatin A induces morphological changes and gelolin expression by inhibiting histone deacetylase in human carcinoma cell lines
-
Y. Hoshikawa, H. J. Kwon, M. Yoshida, S. Horinouchi, and T. Beppu (1994). Trichostatin A induces morphological changes and gelolin expression by inhibiting histone deacetylase in human carcinoma cell lines. Exper. Cell Res. 214:189-197.
-
(1994)
Exper. Cell Res.
, vol.214
, pp. 189-197
-
-
Hoshikawa, Y.1
Kwon, H.J.2
Yoshida, M.3
Horinouchi, S.4
Beppu, T.5
-
80
-
-
0033602765
-
Epigenetic regulation of gelsolin expression in human breast cancer cells
-
L. M. Mielnicki, A. M. Ying, K. L. Head, H. L. Asch, and B. B. Asch (1999). Epigenetic regulation of gelsolin expression in human breast cancer cells. Experi. Cell Res. 249:161-176.
-
(1999)
Experi. Cell Res.
, vol.249
, pp. 161-176
-
-
Mielnicki, L.M.1
Ying, A.M.2
Head, K.L.3
Asch, H.L.4
Asch, B.B.5
-
82
-
-
0025228501
-
Tropomyosins of human mammary epithelial cells: Consistent defects of expression in mammary carcinoma cell lines
-
B. Bhattacharya, G. L. Prasad, E. M. Valverius, D. S. Salomon, and H. L. Cooper (1990). Tropomyosins of human mammary epithelial cells: Consistent defects of expression in mammary carcinoma cell lines. Cancer Res. 50:2105-2112.
-
(1990)
Cancer Res.
, vol.50
, pp. 2105-2112
-
-
Bhattacharya, B.1
Prasad, G.L.2
Valverius, E.M.3
Salomon, D.S.4
Cooper, H.L.5
-
83
-
-
0030966691
-
Defining a role for c-Myc in breast tumorigenesis
-
S. J. Nass and R. B. Dickson (1997). Defining a role for c-Myc in breast tumorigenesis. Breast Cancer Res. Treat. 44:1-22.
-
(1997)
Breast Cancer Res. Treat.
, vol.44
, pp. 1-22
-
-
Nass, S.J.1
Dickson, R.B.2
-
84
-
-
0032739089
-
Determination of c-myc amplification and overexpression in breast cancer patients: Evaluation of its prognostic value against c-erbB-2, cathepsin-D and clinicopathological characteristics using univariate and multivariate analysis
-
A. Scorilas, T. Trangas, J. Yotis, C. Pateras, and M. Talieri (1999). Determination of c-myc amplification and overexpression in breast cancer patients: Evaluation of its prognostic value against c-erbB-2, cathepsin-D and clinicopathological characteristics using univariate and multivariate analysis. Brit. J. Cancer 81:1385-1391.
-
(1999)
Brit. J. Cancer
, vol.81
, pp. 1385-1391
-
-
Scorilas, A.1
Trangas, T.2
Yotis, J.3
Pateras, C.4
Talieri, M.5
-
85
-
-
0034123593
-
Mammary gland neoplasia: Insights from transgenic mouse models
-
P. M. Siegel, W. R. Hardy, and W. J. Muller (2000). Mammary gland neoplasia: Insights from transgenic mouse models. Bioessays 22:554-563.
-
(2000)
Bioessays
, vol.22
, pp. 554-563
-
-
Siegel, P.M.1
Hardy, W.R.2
Muller, W.J.3
-
86
-
-
0034141362
-
Induction of Myc-intron-binding polypeptides MIBP1 and RFX1 during retinoic acid-mediated differentiation of haemopoietic cells
-
M. Zajac-Kaye, N. Ben-Baruch, E. Kastanos, F. J. Kaye, and C. Allegra (2000). Induction of Myc-intron-binding polypeptides MIBP1 and RFX1 during retinoic acid-mediated differentiation of haemopoietic cells. Biochem. J. 345(Pt 3): 535-541.
-
(2000)
Biochem. J.
, vol.345
, Issue.PART 3
, pp. 535-541
-
-
Zajac-Kaye, M.1
Ben-Baruch, N.2
Kastanos, E.3
Kaye, F.J.4
Allegra, C.5
-
87
-
-
0034142186
-
Interactions of the nuclear matrix-associated steroid receptor binding factor with its DNA binding element in the c-myc gene promoter
-
T. J. Barrett, N. P. Sandhu, A. J. Tomlinson, L. M. Benson, M. Subramaniam, S. Naylor, and T. C. Spelsberg (2000). Interactions of the nuclear matrix-associated steroid receptor binding factor with its DNA binding element in the c-myc gene promoter. Biochemistry 39:753-762.
-
(2000)
Biochemistry
, vol.39
, pp. 753-762
-
-
Barrett, T.J.1
Sandhu, N.P.2
Tomlinson, A.J.3
Benson, L.M.4
Subramaniam, M.5
Naylor, S.6
Spelsberg, T.C.7
-
88
-
-
0027316830
-
Rapid alteration of c-myc and c-jun expression in leukemic cells induced to differentiate by a butyric acid prodrug
-
E. Rabizadeh, M. Shaklai, A. Nudelman, L. Eisenbach, and A. Rephaeli (1993). Rapid alteration of c-myc and c-jun expression in leukemic cells induced to differentiate by a butyric acid prodrug. FEBS Lett. 328:225-229.
-
(1993)
FEBS Lett.
, vol.328
, pp. 225-229
-
-
Rabizadeh, E.1
Shaklai, M.2
Nudelman, A.3
Eisenbach, L.4
Rephaeli, A.5
-
89
-
-
0029693220
-
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation
-
C. VanLint, S. Emiliani, and E. Verdin (1996). The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Exp. 5:245-253.
-
(1996)
Gene Exp.
, vol.5
, pp. 245-253
-
-
VanLint, C.1
Emiliani, S.2
Verdin, E.3
-
90
-
-
0034126807
-
Developmental patterning genes and their conserved functions: From model organisms to humans
-
A. Veraksa, M. Del Campo, and W. McGinnis (2000). Developmental patterning genes and their conserved functions: From model organisms to humans. Mol. Genet. Metab. 69:85-100.
-
(2000)
Mol. Genet. Metab.
, vol.69
, pp. 85-100
-
-
Veraksa, A.1
Del Campo, M.2
McGinnis, W.3
-
92
-
-
0031970429
-
Transcriptional interferences at the Hoxa4/Hoxa5 locus: Importance of correct Hoxa5 expression for the proper specification of the axial skeleton
-
J. Aubin, M. Lemieux, M. Tremblay, R. R. Behringer, and L. Jeannotte (1998). Transcriptional interferences at the Hoxa4/Hoxa5 locus: Importance of correct Hoxa5 expression for the proper specification of the axial skeleton. Dev. Dynam. 212:141-156.
-
(1998)
Dev. Dynam.
, vol.212
, pp. 141-156
-
-
Aubin, J.1
Lemieux, M.2
Tremblay, M.3
Behringer, R.R.4
Jeannotte, L.5
-
93
-
-
0034702232
-
Compromized HOXA5 function can limit p53 expression in human breast tumors
-
V. Raman, S. A. Martensen, D. Reisman, E. Evron, W. F. Odenwald, E. Jaffee, J. Marks, and S. Sukumar (2000). Compromized HOXA5 function can limit p53 expression in human breast tumors. Nature 405: 74-978.
-
(2000)
Nature
, vol.405
, pp. 974-978
-
-
Raman, V.1
Martensen, S.A.2
Reisman, D.3
Evron, E.4
Odenwald, W.F.5
Jaffee, E.6
Marks, J.7
Sukumar, S.8
-
95
-
-
0033572467
-
Transforming growth factor-β and breast cancer risk in women with mammary epithelial hyperplasia
-
H. Gobbi, W. D. Dupont, J. F. Simpson, W. D. Plummer, Jr., P. A. Schuyler, S. J. Olson, C. L. Arteaga, and D. L. Page (1999). Transforming growth factor-β and breast cancer risk in women with mammary epithelial hyperplasia. J. Natl. Cancer Inst. 91:2096-2101.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 2096-2101
-
-
Gobbi, H.1
Dupont, W.D.2
Simpson, J.F.3
Plummer Jr., W.D.4
Schuyler, P.A.5
Olson, S.J.6
Arteaga, C.L.7
Page, D.L.8
-
96
-
-
0026028343
-
Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers
-
W. J. Gullick (1991). Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers. Br. Med. Bull. 47:87-98.
-
(1991)
Br. Med. Bull.
, vol.47
, pp. 87-98
-
-
Gullick, W.J.1
-
97
-
-
0021705725
-
Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines
-
Y. H. Xu, N. Richert, S. Ito, G. T. Merlino, and I. Pastan (1984). Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines. Proc. Natl. Acad. Sci. U.S.A. 81:7308-7312.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 7308-7312
-
-
Xu, Y.H.1
Richert, N.2
Ito, S.3
Merlino, G.T.4
Pastan, I.5
-
98
-
-
0021799571
-
Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells
-
G. T. Merlino, S. Ishii, J. Whang-Peng, T. Knutsen, Y. H. Xu, A. J. Clark, R. H. Stratton, R. K. Wilson, D. P. Ma, B. A. Roe, J. H. Hunts, N. Shimizu, and I. Pastan (1985). Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells. Mol. Cell. Biol. 5: 722-1734.
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 1722-1734
-
-
Merlino, G.T.1
Ishii, S.2
Whang-Peng, J.3
Knutsen, T.4
Xu, Y.H.5
Clark, A.J.6
Stratton, R.H.7
Wilson, R.K.8
Ma, D.P.9
Roe, B.A.10
Hunts, J.H.11
Shimizu, N.12
Pastan, I.13
-
99
-
-
0027714992
-
Chromatin structure of the EGFR gene suggests a role for intron 1 sequences in its regulation in breast cancer cells
-
S. A. Chrysogelos (1993). Chromatin structure of the EGFR gene suggests a role for intron 1 sequences in its regulation in breast cancer cells. Nucleic Acids Res. 21:5736-5741.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 5736-5741
-
-
Chrysogelos, S.A.1
-
100
-
-
0343569824
-
Modulation of EGFR gene transcription by a polymorphic repetitive sequence - A link between genetics and epigenetics
-
F. Gebhardt, H. Burger, and B. Brandt (2000). Modulation of EGFR gene transcription by a polymorphic repetitive sequence - a link between genetics and epigenetics. Int. J. Biol. Markers 15:105-110.
-
(2000)
Int. J. Biol. Markers
, vol.15
, pp. 105-110
-
-
Gebhardt, F.1
Burger, H.2
Brandt, B.3
-
101
-
-
0027158895
-
Prognostic value of PS2 and cathepsin D in 710 human primary breast tumors: Multivariate analysis
-
J. A. Foekens, W. L. van Putten, H. Portengen, H. Y. de Koning, B. Thirion, J. Alexieva-Figusch, and J. G. Klijn (1993). Prognostic value of PS2 and cathepsin D in 710 human primary breast tumors: Multivariate analysis. J. Clin. Oncol. 11:899-908.
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 899-908
-
-
Foekens, J.A.1
van Putten, W.L.2
Portengen, H.3
de Koning, H.Y.4
Thirion, B.5
Alexieva-Figusch, J.6
Klijn, J.G.7
-
102
-
-
0033552917
-
Chromatin structure of the regulatory regions of pS2 and cathepsin D genes in hormone-dependent and -independent breast cancer cell lines
-
C. Giamarchi, M. Solanas, C. Chailleux, P. Augereau, F. Vignon, H. Rochefort, and H. Richard-Foy (1999). Chromatin structure of the regulatory regions of pS2 and cathepsin D genes in hormone-dependent and -independent breast cancer cell lines. Oncogene 18: 33-541.
-
(1999)
Oncogene
, vol.18
, pp. 533-541
-
-
Giamarchi, C.1
Solanas, M.2
Chailleux, C.3
Augereau, P.4
Vignon, F.5
Rochefort, H.6
Richard-Foy, H.7
-
103
-
-
0030906551
-
Involvement of DNA methylation in the control of the expression of an estrogen-induced breast-cancer-associated protein (pS2) in human breast cancers
-
V. Martin, S. Ribieras, X. G. Song-Wang, Y. Lasne, L. Frappart, M. C. Rio, and R. Dante (1997). Involvement of DNA methylation in the control of the expression of an estrogen-induced breast-cancer-associated protein (pS2) in human breast cancers. J. Cell Biochem. 65:95-106.
-
(1997)
J. Cell Biochem.
, vol.65
, pp. 95-106
-
-
Martin, V.1
Ribieras, S.2
Song-Wang, X.G.3
Lasne, Y.4
Frappart, L.5
Rio, M.C.6
Dante, R.7
-
105
-
-
0027475947
-
Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells
-
V. Cavailles, P. Augereau, and H. Rochefort (1993). Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc. Natl. Acad. Sci. U.S.A. 90:203-207.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 203-207
-
-
Cavailles, V.1
Augereau, P.2
Rochefort, H.3
-
106
-
-
0028108891
-
Regulation of vimentin gene transcription in human breast cancer cell lines
-
C. L. Sommers, J. M. Skerker, S. A. Chrysogelos, M. Bosseler, and E. P. Gelmann (1994). Regulation of vimentin gene transcription in human breast cancer cell lines. Cell Growth Differ. 5:839-846.
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 839-846
-
-
Sommers, C.L.1
Skerker, J.M.2
Chrysogelos, S.A.3
Bosseler, M.4
Gelmann, E.P.5
-
107
-
-
0039712065
-
Mutation and childhood cancer: A probabilistic model for the incidence of retinoblastoma
-
A. G. Knudson, Jr., H. W. Hethcote, and B. W. Brown (1975). Mutation and childhood cancer: A probabilistic model for the incidence of retinoblastoma. Proc. Natl. Acad. Sci. U.S.A. 72:5116-5120.
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 5116-5120
-
-
Knudson Jr., A.G.1
Hethcote, H.W.2
Brown, B.W.3
-
108
-
-
0033860818
-
Hypomethylation of cytosine 5-methyltransferase in human neoplasms
-
T. L. Butler, P. H. Kay, and P. F. Jacobsen (2000). Hypomethylation of cytosine 5-methyltransferase in human neoplasms. Anticancer Res. 20:1435-1438.
-
(2000)
Anticancer Res.
, vol.20
, pp. 1435-1438
-
-
Butler, T.L.1
Kay, P.H.2
Jacobsen, P.F.3
-
109
-
-
0034104047
-
Mutations truncating the EP300 acetylase in human cancers
-
S. A. Gayther, S. J. Batley, L. Linger, A. Bannister, K. Thorpe, S. F. Chin, Y. Daigo, P. Russell, A. Wilson, H. M. Sowter, J. D. Delhanty, B. A. Ponder, T. Kouzarides, and C. Caldas (2000). Mutations truncating the EP300 acetylase in human cancers. Nat. Genet. 24:300-303.
-
(2000)
Nat. Genet.
, vol.24
, pp. 300-303
-
-
Gayther, S.A.1
Batley, S.J.2
Linger, L.3
Bannister, A.4
Thorpe, K.5
Chin, S.F.6
Daigo, Y.7
Russell, P.8
Wilson, A.9
Sowter, H.M.10
Delhanty, J.D.11
Ponder, B.A.12
Kouzarides, T.13
Caldas, C.14
-
110
-
-
0034466971
-
Acetyltransferases and tumor suppression
-
A. C. Phillips and K. H. Vousden (2000). Acetyltransferases and tumor suppression. Brit. Cancer. Res. 2:244-246.
-
(2000)
Brit. Cancer Res.
, vol.2
, pp. 244-246
-
-
Phillips, A.C.1
Vousden, K.H.2
-
111
-
-
3643104150
-
Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
-
R. P. Warrell, Jr., L-Z. He, V. Richon, E. Calleja, and P. P. Pandolfi (1998). Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J. Natl. Cancer Inst. 90:1621-1625.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 1621-1625
-
-
Warrell Jr., R.P.1
He, L.-Z.2
Richon, V.3
Calleja, E.4
Pandolfi, P.P.5
-
112
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
E. E. Cameron, K. E. Bachman, S. Myohanen, J. G. Herman, and S. B. Baylin (1999). Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat. Genet. 21:103-107.
-
(1999)
Nat. Genet.
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
-
113
-
-
0034071282
-
The intracellular target of butyrate's actions: HDAC or HDONT?
-
[comment]
-
P. R. Gibson (2000). The intracellular target of butyrate's actions: HDAC or HDONT? [comment]. Gut 46:447-448.
-
(2000)
Gut
, vol.46
, pp. 447-448
-
-
Gibson, P.R.1
-
114
-
-
0032539890
-
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
-
V. M. Richon, S. Emiliani, E. Verdin, Y. Webb, R. Breslow, R. A. Rifkind, and P. A. Marks (1998). A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc. Natl. Acad. Sci. U.S.A. 95:3003-3007.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 3003-3007
-
-
Richon, V.M.1
Emiliani, S.2
Verdin, E.3
Webb, Y.4
Breslow, R.5
Rifkind, R.A.6
Marks, P.A.7
-
115
-
-
0020025385
-
Effects of sodium butyrate, a new pharmacological agent, on cells in culture
-
J. Kruh (1982). Effects of sodium butyrate, a new pharmacological agent, on cells in culture. Mol. Cell Biochem. 42:65-82.
-
(1982)
Mol. Cell Biochem.
, vol.42
, pp. 65-82
-
-
Kruh, J.1
-
116
-
-
0025130589
-
Butyrate blocks the accumulation of CDC2 mRNA in late G1 phase but inhibits both the early and late G1 progression in chemically transformed mouse fibroblasts BP-A31
-
R. H. Charollais, C. Buquet, and J. Mester (1990). Butyrate blocks the accumulation of CDC2 mRNA in late G1 phase but inhibits both the early and late G1 progression in chemically transformed mouse fibroblasts BP-A31. J. Cell Physiol. 145:46-52.
-
(1990)
J. Cell Physiol.
, vol.145
, pp. 46-52
-
-
Charollais, R.H.1
Buquet, C.2
Mester, J.3
-
117
-
-
0027661895
-
Effect of sodium butyrate on the expression of retinoblastoma (RB1) and p53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29
-
R. Gope and M. L. Gope (1993). Effect of sodium butyrate on the expression of retinoblastoma (RB1) and p53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29. Cell. Mol. Biol. 39:589-597.
-
(1993)
Cell. Mol. Biol.
, vol.39
, pp. 589-597
-
-
Gope, R.1
Gope, M.L.2
-
118
-
-
0028168478
-
Reciprocal regulation of α-fetoprotein and albumin gene expression by butyrate in human hepatoma cells
-
T. Tsutsumi, A. Ido, K. Nakao, K. Hamasaki, Y. Kato, A. Ohtsuru, K. Nakata, T. Tamaoki, and S. Nagataki (1994). Reciprocal regulation of α-fetoprotein and albumin gene expression by butyrate in human hepatoma cells. Gastroenterology 107:499-504.
-
(1994)
Gastroenterology
, vol.107
, pp. 499-504
-
-
Tsutsumi, T.1
Ido, A.2
Nakao, K.3
Hamasaki, K.4
Kato, Y.5
Ohtsuru, A.6
Nakata, K.7
Tamaoki, T.8
Nagataki, S.9
-
119
-
-
0030785434
-
Effect of sodium butyrate on human breast cancer cell lines
-
D. Coradini, A. Biffi, A. Costa, C. Pellizzaro, E. Pirronello, and G. Di Fronzo (1997). Effect of sodium butyrate on human breast cancer cell lines. Cell Prolif. 30:149-159.
-
(1997)
Cell Prolif.
, vol.30
, pp. 149-159
-
-
Coradini, D.1
Biffi, A.2
Costa, A.3
Pellizzaro, C.4
Pirronello, E.5
Di Fronzo, G.6
-
120
-
-
0030741385
-
Apoptosis death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors
-
J. A. McBain, A. Eastman, C. S. Nobel, and G. C. Mueller (1997). Apoptosis death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. Biochem. Pharmacol. 53: 357-1368.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 1357-1368
-
-
McBain, J.A.1
Eastman, A.2
Nobel, C.S.3
Mueller, G.C.4
-
123
-
-
0028269683
-
A phase I and pharmacokinetic study of intraveneous phenylacetate in patients with cancer
-
A. Thibault, M. R. Cooper, W. D. Figg, D. J. Venzon, A. O. Sartor, A. C. Tompkins, M. S. Weinberger, D. J. Headlee, N. A. McCall, and D. Samid (1994). A phase I and pharmacokinetic study of intraveneous phenylacetate in patients with cancer. Cancer Res. 54: 690-1694.
-
(1994)
Cancer Res.
, vol.54
, pp. 1690-1694
-
-
Thibault, A.1
Cooper, M.R.2
Figg, W.D.3
Venzon, D.J.4
Sartor, A.O.5
Tompkins, A.C.6
Weinberger, M.S.7
Headlee, D.J.8
McCall, N.A.9
Samid, D.10
-
124
-
-
0032546017
-
Role of the histone deacetylase complex in acute promyelocytic leukaemia
-
R. J. Lin, L. Nagy, S. Inoue, W. Shao, W. H. Miller, Jr., and R. M. Evans (1998). Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 391:811-814.
-
(1998)
Nature
, vol.391
, pp. 811-814
-
-
Lin, R.J.1
Nagy, L.2
Inoue, S.3
Shao, W.4
Miller Jr., W.H.5
Evans, R.M.6
-
125
-
-
0033367018
-
Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA)
-
L. A. Cohen, S. Amin, P. A. Marks, R. A. Rifkind, D. Desai, and V. M. Richon (1999). Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA). Anticancer Res. 19: 999-5005.
-
(1999)
Anticancer Res.
, vol.19
, pp. 4999-5005
-
-
Cohen, L.A.1
Amin, S.2
Marks, P.A.3
Rifkind, R.A.4
Desai, D.5
Richon, V.M.6
-
126
-
-
0028258610
-
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity
-
H. Ueda, H. Nakajima, Y. Hori, T. Fujita, M. Nishimura, T. Goto, and M. Okuhara (1994). FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity. J. Antibiot. (Tokyo) 47:301-310.
-
(1994)
J. Antibiot. (Tokyo)
, vol.47
, pp. 301-310
-
-
Ueda, H.1
Nakajima, H.2
Hori, Y.3
Fujita, T.4
Nishimura, M.5
Goto, T.6
Okuhara, M.7
-
127
-
-
0031768386
-
Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells
-
G. Rajgolikar, K. K. Chan, and H. C. Wang (1998). Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells. Breast Cancer Res. Treat. 51:29-38.
-
(1998)
Breast Cancer Res. Treat.
, vol.51
, pp. 29-38
-
-
Rajgolikar, G.1
Chan, K.K.2
Wang, H.C.3
-
128
-
-
0028267278
-
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice
-
H. Ueda, T. Manda, S. Matsumoto, S. Mukumoto, F. Nishigaki, I. Kawamura, and K. Shimomura (1994). FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice. J. Antibiot. (Tokyo) 47:315-323.
-
(1994)
J. Antibiot. (Tokyo)
, vol.47
, pp. 315-323
-
-
Ueda, H.1
Manda, T.2
Matsumoto, S.3
Mukumoto, S.4
Nishigaki, F.5
Kawamura, I.6
Shimomura, K.7
-
129
-
-
0033566643
-
Depsipeptide (FR901228): A novel therapeutic agent with selective, in vitro activity against human B-cell chronic lymphocytic leukemia cells
-
J. Byrd, C. Shinn, R. Ravi, C. Willis, J. Waselenko, I. Flinn, N. Dawson, and M. Grever (1999). Depsipeptide (FR901228): A novel therapeutic agent with selective, in vitro activity against human B-cell chronic lymphocytic leukemia cells. Blood 94:1401-1408.
-
(1999)
Blood
, vol.94
, pp. 1401-1408
-
-
Byrd, J.1
Shinn, C.2
Ravi, R.3
Willis, C.4
Waselenko, J.5
Flinn, I.6
Dawson, N.7
Grever, M.8
-
130
-
-
0030667857
-
Depsipeptide (FR901228, NSC-630176) pharmacokinetics in the rat by LC/MS/MS
-
K. Chan, R. Bakhtiar, and C. Jiang (1997). Depsipeptide (FR901228, NSC-630176) pharmacokinetics in the rat by LC/MS/MS. Invest. New Drugs 15:195-206.
-
(1997)
Invest. New Drugs
, vol.15
, pp. 195-206
-
-
Chan, K.1
Bakhtiar, R.2
Jiang, C.3
-
131
-
-
0011195924
-
Effect of infusion rat on the toxicity of depsipeptide (NSC-630176) in beagle dogs
-
J. G. Page, L. E. Rodman, J. E. Heath, J. E. Tomaszewski, and A. C. Smith (1995). Effect of infusion rat on the toxicity of depsipeptide (NSC-630176) in beagle dogs. Proc. Amer. Assoc. Cancer Res. 36: 68.
-
(1995)
Proc. Amer. Assoc. Cancer Res.
, vol.36
, pp. 368
-
-
Page, J.G.1
Rodman, L.E.2
Heath, J.E.3
Tomaszewski, J.E.4
Smith, A.C.5
|