Microvascular endothelial cell death and rarefaction in the glucocorticoid-induced hypertensive rat

Microcirculation

Volumn 8, Issue 2, 2001, Pages 129-139

  Vogt, Camille J ^a   Schmid Schönbein, Geert W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Arteriole; Capillary; Confocal; Dexamethasone; Ethidium bromide; Fluorescein isothyocyanate; Hoechst 33342; Intravital microscopy; Lectin; Propidium iodide; Venule

Indexed keywords

ANIMALIA; RATTUS NORVEGICUS;

DEXAMETHASONE;

ANIMAL; APOPTOSIS; ARTICLE; BLOOD PRESSURE; CAPILLARY; HYPERTENSION; PATHOLOGY; RAT; SKELETAL MUSCLE; VASCULAR ENDOTHELIUM; VASCULARIZATION; WISTAR RAT;

ANIMALS; APOPTOSIS; BLOOD PRESSURE; CAPILLARIES; DEXAMETHASONE; ENDOTHELIUM, VASCULAR; HYPERTENSION; MUSCLE, SKELETAL; RATS; RATS, WISTAR;

EID: 0035319831     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mn.7300149     Document Type: Article

References (54)

1. Baez S. (1973). An open cremaster muscle preparation for the study of blood vessels by in vivo microscopy. Microvasc Res 5:384-394.
2. Deckers CL, Lyons AB, Samuel K, Sanderson A, Maddy AH. (1993). Alternative pathways of apoptosis induced by methylprednisolone and valinomycin analyzed by flow cytometry. Exp Cell Res 208:362-370.
3. DeLano FA, Matsu MS, Zweifach BW, Schmid-Schönbein GW. (1993). Topography and onset of cell injury in exteriorized organ preparations using microfluorography. FASEB J 7:A882.
4. Gasser P, Buhler FR. (1992). Nailfold microcirculation in normotensive and essential hypertensive subjects, as assessed by video-microscopy. J Hypertens 10:83-86.
5. Gobé G, Browning J, Howard T, Hogg N, Winterford C, Cross R. (1997). Apoptosis occurs in endothelial cells during hypertension-induced microvascular rarefaction. J Struct Biol 118:63-72.
6. Crasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowska K, Bursch W, Schulte-Hermann R. (1995). In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 21:1465-1468.
7. Greene AS, Lombard JH, Cowley AW, Hansen-Smith FW. (1990). Microvessel changes in hypertension measured by Criffonia simplicifolia I lectin. Hypertension 15:779-783.
8. Haack DW, Schaffer JJ, Simpson JG. (1980). Comparisons of cutaneous microvessels from spontaneously hypertensive, normotensive Wistar-Kyoto, and normal Wistar rats. Proc Soc Exp Biol Med 164:453-458.
9. Hamet P, Richard L, Dam TV, Teiger E, Orlov SN, Gaboury L, Gossard F, Tremblay J. (1995). Apoptosis in target organs of hypertension. Hypertension 26: 642-648.
10. Handa M, Kondo K, Suzuki H, Saruta T. (1984). Dexamethasone hypertension in rats: role of prostaglandins and pressor sensitivity to norepinephrine. Hypertension 6:236-241.
11. Hansen-Smith FM, Greene AS, Cowley AJ, Lombard JH. (1990). Structural changes during microvascular rarefaction in chronic hypertension. Hypertension 15:922-928.
12. Hansen-Smith FM, Morris LW, Creene AS, Lombard JH. (1996). Rapid microvessel rarefaction with elevated salt intake and reduced renal mass hypertension in rats. Circ Res 79:324-330.
13. Hansen-Smith FM, Watson L, Lu DY, Goldstein I. (1988). Criffonia simplicifolia I: fluorescent tracer for microcirculatory vessels in nonperfused thin muscles and sectioned muscle. Microvasc Res 36:199-215.
14. Harper RN, Moore MA, Marr MC, Watts LE, Hutchins PM. (1978). Arteriolar rarefaction in the conjunctiva of human essential hypertensives. Microvasc Res 16: 369-372.
15. Heiss JD, Papavassiliou E, Merrill MJ, Nieman L, Knightly JJ, Walbridge S, Edwards NA, Oldfield EH. (1996). Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor. J Clin Invest 98:1400-1408.
16. Henrich H, Hertel R, Assmann R. (1978). Structural differences in the mesentery microcirculation between normotensive and spontaneously hypertensive rats. Pflugers Arch 375:153-159.
17. Hutchins PM, Daruell AE. (1974). Observation of a decreased number of small arterioles in spoutaneously hypertensive rats. Circ Res 34-35(suppl I): 161-165.
18. Kerr JF, Gobé GC, Winterford CM, Harmon BV. (1995). Anatomical methods in cell death. Methods Cell Biol 46:1-27.
19. Kerr JF, Wyllie AH, Currie AR. (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257.
20. Khan AA, Soloski MJ, Sharp AH, Schilling G, Sabatini DM, Li SH, Ross CA, Snyder SH. (1996). Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science 273:503-507.
21. Konagaya M, Bernard PA, Max SR. (1986). Blockade of glucocorticoid receptor binding and inhibition of dexamethasone-induced muscle atrophy in the rat by RU38486, a potent glucocorticoid antagonist. Endocrinology 119:375-380.
22. Krishan A. (1975). Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol 66:188-193.
23. Krishna G, Urda G, Tefera W, Lalwani ND, Theiss J. (1995). Simultaneous evaluation of dexamethasone-induced apoptosis and micronuclei in rat primary spleen cell cultures. Mutat Res 332:1-8.
24. Lemasters JJ, DiGuiseppi J, Nieminen AL, Herman B. (1987). Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes. Nature 325:78-81.
25. Lyons AB, Samuel K, Sanderson A, Maddy AH. (1992). Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry. Cytometry 13:809-821.
26. Meeson AP, Argilla M, Ko K, Witte L, Lang RA. (1999). VEGF deprivation-induced apoptosis is a component of programmed capillary regression. Development 126:1407-1415.
27. Oberhammer F, Bursch W, Tiefenbacher R, Froschl G, Pavelka M, Purchio T, Schulte HR. (1993). Apoptosis is induced by transforming growth factor-beta 1 within 5 hours in regressing liver without significant fragmentation of the DNA. Hepatology 18: 1238-1246.
28. Pirpiris M, Sudhir K, Yeung S, Jennings G, Whitworth JA. (1992). Pressor responsiveness in corticosteroid-induced hypertension in humans. Hypertension 19:567-574.
29. Potter RF, Peters G, Carson M, Forbes T, Ellis CG, Harris KA, DeRose G, Jamieson WG. (1995). Measurement of tissue viability using intravital microscopy and fluorescent nuclear dyes. J Surg Res 59: 521-526.
30. Prewitt RL, Chen H, Dowell R. (1982). Development of microvascular rarefaction in the spontaneously hypertensive rat. Am J Physiol 243:H243-H251.
31. Price RJ, Skalak TC. (1994). Circumferential wall stress as a mechanism for arteriolar rarefaction and proliferation in a network model. Microvasc Res 47: 188-202.
32. Sato A, Suzuki H, Nakazato Y, Shibata H, Inagami T, Saruta T. (1994). Increased expression of vascular angiotensin II type 1A receptor gene in glucocorticoid-induced hypertension. J Hypertens 12:511-516.
33. Schimmer BP, Parker KL. (1996). Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and actions of adrenocortical hormones. In: The Pharmacological Basis of Therapeutics, 9th ed. (JG Hardman, LE Limbird, PB Molinoff, RW Ruddon, and AG Gilman, Eds.) McGraw-Hill, New York: pp. 1459-1485.
34. Schmid-Schönbein GW, Zweifach BW, Kovalcheck S. (1977). The application of stereological principles to morphometry of the microcirculation in different tissues. Microvasc Res 14:303-317.
35. Skalak TC, Schmid-Schönbein GW. (1986). The microvasculature in skeletal muscle. IV. A model of the capillary network. Microvasc Res 32:333-347.
36. Soro A, Ingram MC, Tonolo G, Glorioso N, Fraser R, (1995). Mildly raised corticosterone excretion rates in patients with essential hypertension. J Hum Hypertens 9:391-393.
37. Suematsu M, DeLano FA, Poole D, Engler RL, Miyasaka M, Zweifach BW, Schmid-Schönbein GW, (1994). Spatial and temporal correlation between leukocyte behavior and cell injury in postischemic rat skeletal muscle microcirculation. Lab Invest 70:684-695.
38. Suematsu M, Schmid-Schönbein GW, Chavez-Chavez RH, Yee TT, Tamatani T, Miyasaka M, DeLano FA, Zweifach BW. (1993). In vivo visualization of oxidative changes in microvessels during neutrophil activation. Am J Physiol 264:H881-H891.
39. Suzuki H, DeLano FA, Jamshidi N, Katz D, Mori M, Kosaki K, Gottlieb RA, Ishii H, Smhmid-Schönbein GW. (1999). Enhanced DNA fragmentation in the thymus of spontaneously hypertensive rats. Am J Physiol 276:H2135-H2140.
40. Suzuki H, Handa M, Kondo K, Saruta T. (1982). Role of renin-angiotensin system in glucocorticoid hypertension in rats. Am J Physiol 243:E48-E51.
41. Suzuki H, Swei A, Zweifach BW, Schmid-Schönbein GW. (1995). In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hydroethidine microfluorography. Hypertension 25: 1083-1089.
42. Suzuki H, Zweifach BW, Forrest MJ, Schmid-Schönbein GW. (1995). Modification of leukocyte adhesion in spontaneously hypertensive rats by adrenal corticosteroids. J Leukoc Biol 57:20-26.
43. Tonolo G, Fraser R, Connell JM, Kenyon CJ. (1988). Chronic low-dose infusions of dexamethasone in rats: effects on blood pressure, body weight and plasma atrial natriuretic peptide. J Hypertens 6:25-31.
44. Underwood EE. (1970). Quantitative Stereology. Addison-Wesley, Reading, MA.
45. Vogt CJ. (1999). Microvaseular oxidative injury, endothelial cell death, and capillary rarefaction in glucocorticoid-induced hypertension. Ph.D. Thesis, University of California, San Diego.
46. Walker BR, Best R, Shackleton CH, Padfield PL, Edwards CR. (1996). Increased vasoconstrictor sensitivity to glucocorticoids in essential hypertension. Hypertension 27:190-196.
47. Watt GC, Harrap SB, Foy CJ, Holton DW, Edwards HV, Davidson HR, Connor JM, Lever AF, Fraser R. (1992). Abnormalities of glucocorticoid metabolism and the renin-angiotensin system: a four-corners approach to the identification of genetic determinants of blood pressure. J Hypertens 10:473-482.
48. Whitworth JA. (1987). Mechanisms of glucocorticoid-induced hypertension [clinical conference]. Kidney Int 31:1213-1224.
49. Whitworth JA, Brown MA, Kelly JJ, Williamson PM. (1995). Mechanisms of cortisol-induced hypertension in humans. Steroids 60:76-80.
50. Wu CH, Chi JC, Jerng JS, Lin SJ, Jan KM, Wang DL, Chien S. (1990). Transendothelial macromolecular transport in the aorta of spontaneously hypertensive rats. Hypertension 16:154-161.
51. Wyllie AH. (1980). Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endo-nuclease activation. Nature 284:555-556.
52. Yanovski JA, Cutler GB. (1994). Glucocorticoid action and the clinical features of Cushing's syndrome. Endocrinol Metab Clin North Am 23:487-509.
53. Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B, Kroemer G. (1995). Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182:367-377.
54. Zweifach BW, Kovalcheck S, DeLano F, Chen P. (1981). Micropressure-flow relationship in a skeletal muscle of spontaneously hypertensive rats. Hypertension 3:601-614.