Studies of the interactions between melatonin and 2 Hz, 0.3 mT PEMF on the proliferation and invasion of human breast cancer cells

Bioelectromagnetics

Volumn 22, Issue 3, 2001, Pages 178-184

  Leman, Eddy S ^a   Sisken, Betty F ^b   Zimmer, Stephen ^c   Anderson, Kimberly W ^b,d  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d NONE   (United States)

Author keywords

Invasion; Melatonin; Metastasis; PEMF; Proliferation

Indexed keywords

CANCER CELLS; CYTOLOGY; DISEASES; ELECTROMAGNETIC FIELDS; HORMONES; PATHOLOGY; TISSUE;

CELL-BE; CELL/B.E; CELL/BE; HUMAN BREAST CANCER CELLS; INVASION; MDA-MB-231; MELATONIN; METASTASIS; PROLIFERATION; PULSED ELECTROMAGNETIC FIELDS;

CELLS;

MINK CELL FOCUS-FORMING VIRUS;

MELATONIN;

ARTICLE; BREAST TUMOR; CANCER INVASION; CELL CULTURE; CELL DIVISION; DRUG EFFECT; ELECTROMAGNETIC FIELD; FEMALE; HUMAN; METASTASIS; PATHOLOGY; RADIATION EXPOSURE;

BREAST NEOPLASMS; CELL DIVISION; ELECTROMAGNETIC FIELDS; FEMALE; HUMANS; MELATONIN; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; TUMOR CELLS, CULTURED;

EID: 0035316370     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/bem.36     Document Type: Article

References (35)

1. Bartsch H, Bartsch C, Noteborn HPJM, Flehming B, Ebels I, Salemic CA. 1987. Growth inhibiting effect of crude pineal gland extracts on human melanoma cells in vitro is different from that of known synthetic pineal substances. J Neural Trans 69:299-311.
2. Bartsch C, Bartsch M, Simon E, Flehmig B, Ebels I, Lipert TH. 1992. Antitumor activity of the pineal gland: effect of unidentified substances versus the effect of melatonin. Oncology 49:27-30.
3. Blackman CF et al. 1996. Independent Replication of the 12 mG magnetic field effect on melatorin and MCF-7 cells in vitro. BEMS Meeting, Victoria, British Columbia, Canada. Abstract A-1-2.
4. Blask DE, Lemus-Wilson A, Wilson ST. 1992. Breast cancer a model system for studying the effects of pineal melatonin in oncology. Biochem Soc Trans 20:309-311.
5. Boghaert ER, Simpson JF, Zimmer SG. 1992. Invasion in vitro of malignant hamster brain tumor cells is influenced by the number of cells and the mode of malignant progression. Invasion and Metastasis 12:12-23.
6. Cos S, Blask DE, Lemus-Wilson A. Hill B. 1991. Effects of melatonin on the cell cycle kinetics and estrogen-rescue of MCF-7 human breast cancer cells in culture. J Pineal Res 10:36-42.
7. Costa EJX, Lopes RH, Lamy-Freund MT. 1995. Permeability of pure lipid bilayers to melatonin. J Pineal Res 19:123-126.
8. Hill SM, Blask DE. 1988. Effects of pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture. Cancer Res 48:6121-6126.
9. Ito H, Basset CAL. 1983. Effects of weak, pulsing electromagnetic fields on neural regeneration in the rat. Clin Orthop Rel Res 181:283-290.
10. Kanje M, Rusovan A, Sisken BF, Lundborg G. 1993. Pretreatment of rats with pulsed electromagnetic fields enhance regeneration of the rat sciatic nerve. Bioelectromagnetics 14: 353-360.
11. L'Hermite-Baleriaux M, De Launoit Y De. 1992. Is melatonin really an in vitro inhibitor of human breast cancer cell proliferation? In Vitro Cell Dev Biol 52:269-279.
12. + breast cancer cell proliferation. J Pineal Res 14:89-97.
13. Luben RA, Saraiya S, Morgan AP. 1996. Replication of 12 mG electromagnetic field effects on melatonin responses of MCF-7 breast cancer cells in vitro. Annual review of research on biological effects of electric and magnetic fields from the generation, delivery, and use of electricity, San Antonio, Texas, November 19-21. Abstract A-1.
14. Matanoski GM, Breyese PN, Elliot EA. 1991. Electromagnetic field exposure and male breast cancer. Lancet 33:737.
15. Miller DL, Sisken BF, Anderson LE. 1996. Dosimetry of pulsed electromagnetic field treatment of the sciatic nerve in rats. Eighteenth Annual Bioelectromagnetics Society Meeting, Boston, MA (abstract).
16. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
17. Okada T, Okuno H, Mitsui Y. 1994. A novel in vitro assay system for transendothelial tumor cell invasion: significance of E-selectin and alpha-3 integrin in the transendothelial invasion by HT1080 fibrosarcoma cells. Clin Exp Metastasis 12:305-314.
18. Panzer A, Viljoen M. 1997. The validity of melatonin as an oncostatic agent. J Pineal Res 22:184-202.
19. Price JE. 1996. Metastasis from human breast cancer cell lines. Breast Cancer Res Treat 39:93-102.
20. Raji ARM, Bowden REM. 1983. Effects of high peak pulsed electromagnetic field on the degeneration and regeneration of the common peroneal nerve in rats. J Bone Jt Surgery 65:478-492.
21. Ramos DM, Cheng YM, Kramer RH. 1991. Role of laminin-binding integrin in the invasion of basement membrane matrices by fibrosarcoma cells. Invasion Metastasis 11:125-138.
22. Reiter RJ. 1992. Changes in circadian melatonin synthesis in the pineal gland of animals exposed to extremely low frequency electromagnetic radiation: a summary of observations and speculation on their implications. In: Moore-Ede MC, Campbell SS, Reiter RJ, editors. Electromagnetic fields and circadian rhythmicity. Boston: Birkhauser. p 13-17.
23. Rosen LA, Barber I, Lyle DB. 1998. A 0.5 G, 60 Hz magnetic field suppresses melatonin production in pinealocytes. Bioelectromagnetics 19:123-127.
24. Shafie SM, Liotta LA. 1980. Formation of metastasis by human breast carcinoma cells (MCF-7) in nude mice. Cancer Lett 11:81-87.
25. Shellard SA, Whelan RDH, Hill BT. 1989. Growth inhibitory and cytotoxic effects of melatonin and its metabolites on human tumor cell lines in vitro. Brit J Cancer 60:288-290.
26. Sisken BF, Kanje M, Lundborg G, Herbst E, Kurtz W. 1989. Stimulation of rat sciatic nerve regeneration with pulsed electromagnetic field. Brain Res 485:309-316.
27. Sisken BF, Kanje M, Lunborg G, Kurtz W. 1990. Pulsed electromagnetic fields stimulate nerve regeneration in vitro and in vivo. Restor Neurol Neurosci 1:24.
28. Sisken BF, Mullins R. 1991. The importance of the electric vs magnetic fields in studies of neuronal regeneration in vitro. Trans Bioelect Repair Growth Soc 11:28.
29. Stevens R. 1987. Electric power use and breast cancer: a hypothesis. Am J Epidemiol 125:556-561.
30. Stevens RG, Davis S, Thomas DB, Anderson LE, Wilson BW. 1992. Electric power, pineal function and the risk of breast cancer. FASEB J 6:853-863.
31. Terranova VP, Maslow DE. 1991. Interactions of tumor cells with basement membranes. In: Orr FW, Buchanan MR, Weiss L, editors. Microcirculation in cancer metastasis. CRC Press, Inc. p 23-43.
32. Ubeda A, Trillo MA, House DE, Blackman CF. 1995. Melatonin enhances junctional transfer in normal C3H/10T1/2 cells. Cancer Lett 91:241-245.
33. Walker J, Evans JM, Resig P, Guarnieri S, Meade P, Sisken BF. 1994. Enhancement of functional recovery following crush lesion to the rat sciatic nerve by exposure to pulsed electromagnetic fields. Exp Neurol 125:302-305.
34. Wilson BW, Wright CW, Morris JE, Busch-Bom RL, Brown DP, Miller DL, Sommers-Flannigan R, Anderson LE. 1990. Evidence for an effect on ELF electromagnetic fields on human pineal gland function. J Pineal Res 9:259-269.
35. Zhang RD, Ridler IJ, and Price JE. 1991. Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and brain metastasis. Invasion and Metastasis 11:204-215.