The morphine-binding site on human activated T-cells is not related to the mu opioid receptor

Drug and Alcohol Dependence

Volumn 62, Issue 2, 2001, Pages 131-139

  Madden, John J ^a   Whaley, William L ^a   Ketelsen, David ^a   Donahoe, Robert M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene induction; Mitogen; Morphine; Mu receptor; T lymphocyte

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; BETA ENDORPHIN; INTERLEUKIN 2; MESSENGER RNA; MORPHINE; MU OPIATE RECEPTOR; NALOXONE;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG BINDING; DRUG BINDING SITE; DRUG RECEPTOR BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; STEREOCHEMISTRY; T LYMPHOCYTE ACTIVATION;

BINDING SITES; BINDING, COMPETITIVE; CALCIUM; DNA PRIMERS; HUMANS; INTERLEUKIN-2; MORPHINE; NARCOTICS; RECEPTORS, OPIOID, MU; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM; T-LYMPHOCYTES;

EID: 0035314025     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(00)00183-6     Document Type: Article

References (30)

1. Action de la morphine sur les proprietes leucocytaires
2. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta, or kappa receptor type
3. Nouvelles recherches sur le mode de destruction des vibrions dans l'organisme
4. The relevance of opioids and opioid receptors on immunocompetence and immune homeostasis
5. Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors
6. Mu opioid receptor expression in immune cells
7. Functional role and sequence analysis of a lymphocyte orphan opioid receptor
8. Natural killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell
9. Opiate binding to cells of the immune system
10. Binding of naloxone to human T lymphocytes
11. Mitogenic activation of human T lymphocytes induces a high affinity morphine-binding site
12. Opiate binding sites in the cellular immune system: Expression and regulation
13. Genomic structure and analysis of promoter sequences of a mouse mu opioid receptor gene
14. Characterization of opiate binding sites on membranes of rat lymphocytes
15. The porcine mu opioid receptor: Molecular cloning and mRNA distribution in lymphoid tissues
16. Molecular biology of opiate receptors
17. 3H-Morphine binding is enhanced by IL-1 stimulated thymocyte proliferation
18. β-Endorphin binding to naloxone-insensitive sites on a human monocyte cell line (U937): Effects of cations and guanosine triphosphate
19. Nucleotide sequence of Moloney murine leukaemia virus
20. 3 opiate receptor in endothelial cells
21. Mu opiate receptor: cDNA cloning and expression
22. Human Mu opiate receptor: cDNA and genomic clones, pharmacologic characterization and chromosomal assignment
23. Interactions between the neuroendocrine and immune system: Common hormones and receptors
24. Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines
25. Differential expression of opioid receptor genes in human lymphoid cell lines and peripheral blood lymphocytes
26. Suggestive evidence for receptors for morphine and methionine-enkephalin on normal human blood T-lymphocytes
27. Mu opiate receptor down-regulation by morphine and up regulation by naloxone in SH5Y5Y human neuroblastoma cells