Local hyperthermia, radiation, and chemotherapy in recurrent breast cancer is feasible and effective except for inflammatory disease

International Journal of Radiation Oncology Biology Physics

Volumn 49, Issue 5, 2001, Pages 1317-1325

  Feyerabend, Thomas ^a,b   Wiedemann, Günter Joseph ^a   Jäger, Birgit ^a   Vesely, Hugo ^a   Mahlmann, Birgit ^a   Richter, Eckart ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b Department of Radiation Oncology and Nuclear Medicine ^*  (Germany)

Author keywords

Cisplatin; Ifosfamide; Local hyperthermia; Radiation; Recurrent breast cancer

Indexed keywords

CHEMOTHERAPY; PATIENT MONITORING; RADIOTHERAPY; TOXICITY; TUMORS;

BREAST CANCER; INFLAMMATORY DISEASE;

HYPERTHERMIA THERAPY;

EPIRUBICIN; IFOSFAMIDE;

ADULT; AGED; BONE MARROW EXAMINATION; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; FEASIBILITY STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERTHERMIC THERAPY; INFLAMMATORY DISEASE; INOPERABLE CANCER; KIDNEY FUNCTION; LIFE EXPECTANCY; LIVER FUNCTION; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RECURRENT CANCER; WORLD HEALTH ORGANIZATION;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; EPIRUBICIN; FEASIBILITY STUDIES; FEMALE; HUMANS; HYPERTHERMIA, INDUCED; IFOSFAMIDE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RADIOTHERAPY DOSAGE;

EID: 0035312170     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(00)01514-5     Document Type: Conference Paper

References (53)

1. Local recurrences in patients with breast cancer at the North Carolina Memorial Hospital (1970-1982)
2. Radiation therapy in operable breast cancer; Results from the Stockholm Trial in adjuvant radiotherapy
3. Ten-year results from the National Surgical Adjuvant Breast and Bowel Project (NSABP). Clinical trials evaluating the use of L-phenylalanine mustard (L-PAM) in the management of primary breast cancer
4. Identification of a subgroup of patients with breast cancer and histologically positive nodes receiving adjuvant chemotherapy who may benefit from postoperative radiotherapy
5. Analysis of failures following local treatment of isolated local-regional recurrence of breast cancer
6. The use of radiotherapy for treatment of isolated locoregional recurrence of breast carcinoma after mastectomy
7. Prognostic indicators in patients with isolated local-regional recurrence of breast cancer
8. Reirradiation combined with hyperthermia in recurrent breast cancer results in a worthwhile local palliation
9. Locally recurrent carcinoma of the breast; Results of radiation therapy
10. Prognosis and treatment of loco-regional breast cancer recurrences; Critical considerations on 120 cases
11. Isolated local-regional recurrence of breast cancer following mastectomy; Radiotherapeutic management
12. Management of locoregional recurrent breast cancer
13. Prognosticators in recurrent breast cancer; A 15-year experience with irradiation
14. Tumors growing in irradiated tissue; Oxygenation, metabolic state, and pH
15. The current and potential role of hyperthermia in radiotherapy
16. Thermal influence on radiation induced complications versus tumor response in a phase III randomized trial
17. Prognostic factors for tumor response after hyperthermia and radiation
18. An update of the University of Arizona human clinical hyperthermia experience including estimates of therapeutic advantage
19. A phase I-II trial of cisplatin, hyperthermia and radiation in patients with locally advanced malignancies
20. Hyperthermia and irradiation for locally recurrent previously irradiated breast cancer
21. Tumour response to heat and radiation; Prognostic variables in the treatment of neck node metastases from head and neck cancer
22. Quality assurance problems in clinical hyperthermia and their impact on therapeutic outcome; A report by the radiation therapy oncology group
23. Interaction of heat and drugs in vitro and in vivo
24. Biologic basis of thermotherapy
25. Inflammatory breast cancer; Enhanced local control with hyperfractionated radiotherapy and infusional vincristine, ifosfamide and epirubicin
26. Local hyperthermia enhances cyclophosphamide, ifosfamide and cis-diamminedichloroplatinum cytotoxicity on human derived breast carcinoma and sarcoma xenografts in nude mice
27. Interaction of hyperthermia and cis-diamminedichloroplatinum(II) alone or combined with radiation in a C3H mammary carcinoma in vivo
28. Biophysical aspects of the integrated combination of cytotoxic drugs with radiotherapy. ; Part 3: In vivo investigations on murine C3H mammary adenocarcinoma treated with cis-platinum, adriamycin, epirubicin, activated cyclophosphamide, activated isophosphamide and irradiation with 10 MeV electrons-Verification of the therapeutic results with 31P-NMR spectroscopy
29. Palliative chemo-radiotherapy with ifosfamide and epirubicin as first-line treatment for high-risk metastatic breast cancer. Results of a prospective multicenter trial
30. Response of previously irradiated skin to combinations of X-radiation, hyperthermia and cis-diamminedi-chloroplatinum
31. Clinical hyperthermia combined with drugs and radiation. A phase I/II study
32. Thermo-chemo-radiotherapy of esophageal cancer. A preliminary report of 34 cases
33. Radiation, pepleomycin and hyperthermia in the therapy of locally advanced squamous cell carcinomas of the buccal mucosa
34. Retrospective analysis of hyperthermia for use in the palliative treatment of cancer; A multi-modality evaluation
35. Effects of temperature on the therapeutic efficacy and pharmacokinetics of ifosfamide
36. Hyperthermia enhances mitoxantrone cytotoxicity on human breast carcinoma and sarcoma xenografts in nude mice
37. 2 in well oxygenated xenotransplanted human sarcoma
38. The morphology of xenotransplanted human breast cancer MX 1 growing in nude mice. A light and transmission electron microscopic study
39. Local hyperthermia, radiation, and chemotherapy in locally advanced malignancies
40. Hyperthermia improves local tumour control in locally advanced breast cancer
41. Cisplatin, hyperthermia, and radiation (trimodal therapy) in patients with locally advanced head and neck tumors; A phase I-II study
42. Local hyperthermia, radiation therapy, and chemotherapy in patients with local-regional recurrence of breast carcinoma
43. Local hyperthermia of N2/N3 cervical lymph node metastases; correlation of technical/thermal parameters and response
44. Prospective randomized study of hyperthermia combined with chemoradiotherapy for esophageal carcinoma
45. Clinical results of treatment of advanced esophageal carcinoma with hyperthermia in combination with chemoradiotherapy
46. Preoperative hyperthermia combined with radiochemotherapy in locally advanced rectal cancer; A phase II clinical trial
47. Radiation, therapy cisplatin and hyperthermia in combination in management of patients with recurrent carcinomas of the head and neck with metastatic cervical lymph nodes
48. A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer
49. Rationale and clinical status of local hyperthermia, radiation, and chemotherapy in locally advanced malignancies
50. Efficacy of adjuvant hyperthermia in the treatment of superficial recurrent breast cancer; Confirmation and future directions
51. Superficial hyperthermia and irradiation for recurrent breast carcinoma of the chest wall; Prognostic factors in 196 tumors
52. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer; Results from five randomized controlled trials. International Collaborative Hyperthermia Group