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Volumn 36, Issue 3, 2001, Pages 265-286

Synthesis and structure-activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores

(3) Ho, Bin a Michael Crider, A a Stables, James P b

a UNIVERSITY OF LOUISIANA AT MONROE (United States)

b NINDSP (United States)

Author keywords

2,6 dimethylanilides; Anticonvulsant; Carboxamides; Maximal electroshock seizure test; Rotorod test

Indexed keywords

2 AMINO N [(2,6 DIMETHYL)PHENYL]HEXANEAMIDE; AMIDE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; N (2,6 DIMETHYL)PHENYL 2 PIPERIDINECARBOXAMIDE; N (ALPHA METHYLBENZYL) 2 PIPERIDINECARBOXAMIDE; N [(2,6 DIMETHYL)PHENYL] 4 PYRIDINECARBOXAMIDE; PHENYTOIN; PIPECOLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FOCAL EPILEPSY; MOUSE; NEUROTOXICITY; NONHUMAN; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; TONIC CLONIC SEIZURE;

ANIMALS; ANTICONVULSANTS; CARBOXYLIC ACIDS; DRUG EVALUATION, PRECLINICAL; MICE; PIPERIDINES; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TOXICITY TESTS;

EID: 0035310335 PISSN: 02235234 EISSN: None Source Type: Journal
DOI: 10.1016/S0223-5234(00)01206-X Document Type: Article

Times cited : (168)

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