Synthesis and antiplatelet activity of some 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives

Farmaco

Volumn 56, Issue 4, 2001, Pages 311-318

  Ferrarini, Pier Luigi ^a   Badawneh, Muwaffag ^b   Franconi, Flavia ^c   Manera, Clementina ^a   Miceli, Mauro ^d   Mori, Claudio ^a   Saccomanni, Giuseppe ^a  

^a UNIVERSITY OF PISA   (Italy)

^b PHILADELPHIA UNIVERSITY   (Jordan)

^c UNIVERSITY OF SASSARI   (Italy)

^d Dipartmento di Biologia   (Italy)

Author keywords

2,7 Di(N cycloamino) 3 phenyl 1,8 naphthyridine; Human blood platelets; Inhibition of platelet aggregation; Morpholinyl; Piperazinyl; Piperidinyl

Indexed keywords

1,8 NAPHTHYRIDINE DERIVATIVE; 6 AMINO 2 (N ETHOXYCARBONYLPIPERAZIN 1 YL) 3 PHENYL 7 (1 PIPERAZINYL) 1,8 NAPHTHYRIDINE; 6 AMINO 7 (N ETHOXYCARBONYLPIPERAZIN 1 YL) 3 PHENYL 2 (1 PIPERAZINYL) 1,8 NAPHTHYRIDINE; 7 MORPHOLINO 3 PHENYL 2 (PIPERAZIN 1 YL) 1,8 NAPHTHYRIDINE; ADENOSINE DIPHOSPHATE; ADENYLATE CYCLASE; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; COLLAGEN; CYCLIC AMP; IBUPROFEN; INDOMETACIN; PAPAVERINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; THROMBOCYTE AGGREGATION INHIBITION; TURBIDIMETRY;

ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; BLOOD PLATELETS; CHEMISTRY, PHYSICAL; COLLAGEN; CYCLIC AMP; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; NAPHTHYRIDINES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035305750     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01075-8     Document Type: Article

References (8)

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4. Ferrarini P.L., Mori C., Badawneh M., Franconi F., Manera C., Miceli M., Saccomanni G. Synthesis and antiplatelet activity of some 3-phenyl-1,8-naphthyridine derivatives. Farmaco. 55:2000;603-610. (and references therein).
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