-
1
-
-
0014222377
-
An enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis
-
Seegmiller J.E., Rosenbloom F.M., Kelley W.N. (1967) An enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis. Science. 155, 1682-1684.
-
(1967)
Science
, vol.155
, pp. 1682-1684
-
-
Seegmiller, J.E.1
Rosenbloom, F.M.2
Kelley, W.N.3
-
2
-
-
0021966093
-
Self mutilation in the Lesch-Nyhan disease is caused by dopaminergic denervation
-
Goldstein M., Anderson H., Reuben R., Dancis J. (1985) Self mutilation in the Lesch-Nyhan disease is caused by dopaminergic denervation. The Lancet. 8424, 338-339.
-
(1985)
The Lancet
, vol.8424
, pp. 338-339
-
-
Goldstein, M.1
Anderson, H.2
Reuben, R.3
Dancis, J.4
-
3
-
-
0023888809
-
Lesch-Nyhan syndrome: A study of motor behavior and cerebrospinal fluid neurotransmitters
-
Janovitch J., Caskey T.C., Stout T.J., Butler I.J. (1988) Lesch-Nyhan syndrome: a study of motor behavior and cerebrospinal fluid neurotransmitters. Ann. Neurol. 23, 466-469.
-
(1988)
Ann. Neurol.
, vol.23
, pp. 466-469
-
-
Janovitch, J.1
Caskey, T.C.2
Stout, T.J.3
Butler, I.J.4
-
4
-
-
0023150598
-
HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
-
Hooper M., Hardy K., Handyside A. (1987) HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature. 326, 292-295.
-
(1987)
Nature
, vol.326
, pp. 292-295
-
-
Hooper, M.1
Hardy, K.2
Handyside, A.3
-
5
-
-
0026448598
-
Functonal analysis of brain dopaminergic systems in a genetic mouse model of Lesch-Nyhan syndrome
-
Jinnah H.A., Langlais P.J., Friedmann T. (1992) Functonal analysis of brain dopaminergic systems in a genetic mouse model of Lesch-Nyhan syndrome. J. Pharmacol. Exp. Therap. 263, 596-607.
-
(1992)
J. Pharmacol. Exp. Therap.
, vol.263
, pp. 596-607
-
-
Jinnah, H.A.1
Langlais, P.J.2
Friedmann, T.3
-
6
-
-
0028218268
-
Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease
-
Jinnah H.A., Woicik B.E., Hunt M., Narang N., Lee K.Y., Goldstein M., Wamsley K., Langlais P.J., Friedmann T. (1994) Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease. J. Neurosci. 14, 1164-1175.
-
(1994)
J. Neurosci.
, vol.14
, pp. 1164-1175
-
-
Jinnah, H.A.1
Woicik, B.E.2
Hunt, M.3
Narang, N.4
Lee, K.Y.5
Goldstein, M.6
Wamsley, K.7
Langlais, P.J.8
Friedmann, T.9
-
7
-
-
0035957854
-
Decelareted rate of dendrite outgrowth from cultured HPRT-deficient dopaminergic neurons
-
Boer P., Brosh S., Wasserman L., Hammel I., Zoref-Shani E., Sperling O. (2001) Decelareted rate of dendrite outgrowth from cultured HPRT-deficient dopaminergic neurons. Neuroscience Letters. 303, 45-48.
-
(2001)
Neuroscience Letters
, vol.303
, pp. 45-48
-
-
Boer, P.1
Brosh, S.2
Wasserman, L.3
Hammel, I.4
Zoref-Shani, E.5
Sperling, O.6
-
8
-
-
0034039563
-
Elevated UTP and CTP content in cultured neurons from HPRT-deficient transgnic mice
-
Brosh S., Boer P., Sperling O., Zoref-Shani E. (2000) Elevated UTP and CTP content in cultured neurons from HPRT-deficient transgnic mice. J. Molecular Neuroscience. 14, 87-91.
-
(2000)
J. Molecular Neuroscience
, vol.14
, pp. 87-91
-
-
Brosh, S.1
Boer, P.2
Sperling, O.3
Zoref-Shani, E.4
-
9
-
-
0033047986
-
Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from HGPRT-deficient transgenic mice
-
Felled D., Sperling O. Zoref-Shani E. (1999) Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from HGPRT-deficient transgenic mice. J. Neurochemistry. 72, 1139-1145.
-
(1999)
J. Neurochemistry
, vol.72
, pp. 1139-1145
-
-
Felled, D.1
Sperling, O.2
Zoref-Shani, E.3
-
10
-
-
0027216829
-
Characterization of the alteration in purine nucleotide metabolism in HPRT-deficient rat neuroma cell line
-
Zoref-Shani E., Bromberg Y., Brosh S., Sidi Y., Sperling O. (1993). Characterization of the alteration in purine nucleotide metabolism in HPRT-deficient rat neuroma cell line. J. Neurochemistry. 61, 457-463.
-
(1993)
J. Neurochemistry
, vol.61
, pp. 457-463
-
-
Zoref-Shani, E.1
Bromberg, Y.2
Brosh, S.3
Sidi, Y.4
Sperling, O.5
-
11
-
-
0025228831
-
Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain
-
Brosh S., Sperling O., Bromberg Y., Sidi Y. (1990) Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain. J. Neurochem. 54, 1776-1781.
-
(1990)
J. Neurochem.
, vol.54
, pp. 1776-1781
-
-
Brosh, S.1
Sperling, O.2
Bromberg, Y.3
Sidi, Y.4
-
12
-
-
0026580805
-
Metabolism of guanine and guanine nucleotides in primary rat neuronal cultures
-
Brosh S., Sperling O., Dantziger E., Sidi Y. (1992) Metabolism of guanine and guanine nucleotides in primary rat neuronal cultures. J. Neurochem. 58, 1485-1490.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1485-1490
-
-
Brosh, S.1
Sperling, O.2
Dantziger, E.3
Sidi, Y.4
-
13
-
-
0023688982
-
Lesch-Nyhan syndrome and its pathogenesis: Purine concentrations in plasma and urine with metabolite profiles in CSF
-
Harkness R.A., McCreanor G.M., Watts R.W.E. (1988) Lesch-Nyhan syndrome and its pathogenesis: purine concentrations in plasma and urine with metabolite profiles in CSF. J. Inher. Metab. Dis. 11, 239-252.
-
(1988)
J. Inher. Metab. Dis.
, vol.11
, pp. 239-252
-
-
Harkness, R.A.1
McCreanor, G.M.2
Watts, R.W.E.3
-
14
-
-
0019216999
-
Purines as endogenous ligands of the benzodiazepine receptor
-
Skolnick S., Paul S.M., Marangos P.J. (1980) Purines as endogenous ligands of the benzodiazepine receptor. Fed. Proc. 39, 3050-3055.
-
(1980)
Fed. Proc.
, vol.39
, pp. 3050-3055
-
-
Skolnick, S.1
Paul, S.M.2
Marangos, P.J.3
-
15
-
-
0347461275
-
Identification of inosine and hypoxanthine as endogenous ligands for the brain benzodiazepine-binding sites
-
Asano K., Spector S. (1979) Identification of inosine and hypoxanthine as endogenous ligands for the brain benzodiazepine-binding sites. Proc. Natl. Acad. Sci. USA :76 977-981.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 977-981
-
-
Asano, K.1
Spector, S.2
-
16
-
-
0018908662
-
Activities of amidophosphoribosyl-transferase (EC 2.4.2.14) and the purine phosphoribosyltransferase (EC2.4.2.7 and 2.4.2.8) and the phosphoribosylpyrophosphate content of rat central nervous system at different stages of development
-
Allsop J., Watts R.W.E. (1980) Activities of amidophosphoribosyl-transferase (EC 2.4.2.14) and the purine phosphoribosyltransferase (EC2.4.2.7 and 2.4.2.8) and the phosphoribosylpyrophosphate content of rat central nervous system at different stages of development. J. Neurol Sci, 46, 221-223.
-
(1980)
J. Neurol Sci
, vol.46
, pp. 221-223
-
-
Allsop, J.1
Watts, R.W.E.2
-
17
-
-
0022396333
-
Z-nucleotide accumulation in erythrocytes from Lesch-Nyhan patients
-
Sidi Y, Mitchell B.S. (1985) Z-nucleotide accumulation in erythrocytes from Lesch-Nyhan patients. J. Clin. Invest. 76, 2416-2419.
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 2416-2419
-
-
Sidi, Y.1
Mitchell, B.S.2
-
18
-
-
0017431091
-
Purine and pyrimidine nucleotide concentrations in cells with decreased hypoxanthine-guanine phosphoribosyltransferase activity
-
Nuki G., Astrin K., Brenton D., Cruikshank M., Lever J., Seegmiller J.E. (1977) Purine and pyrimidine nucleotide concentrations in cells with decreased hypoxanthine-guanine phosphoribosyltransferase activity. Adv. Exp. Med. Biol. 76A, 326-340.
-
(1977)
Adv. Exp. Med. Biol.
, vol.76 A
, pp. 326-340
-
-
Nuki, G.1
Astrin, K.2
Brenton, D.3
Cruikshank, M.4
Lever, J.5
Seegmiller, J.E.6
-
19
-
-
0029620198
-
Developmental changes in purine nucleotide metabolism in cultured rat astroglia
-
Zoref-Shani E., Bromberg Y., Lilling G., Gozes I., Brosh S., Sidi Y., Sperling, O. (1995) Developmental changes in purine nucleotide metabolism in cultured rat astroglia. Int. J. Develop. Neurosci. 13, 887-896.
-
(1995)
Int. J. Develop. Neurosci.
, vol.13
, pp. 887-896
-
-
Zoref-Shani, E.1
Bromberg, Y.2
Lilling, G.3
Gozes, I.4
Brosh, S.5
Sidi, Y.6
Sperling, O.7
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