Effects of sex hormones on apoptosis in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

Chinese Medical Journal

Volumn 114, Issue 3, 2001, Pages 291-293

  Liu, Chao ^a   Zhou, Hui ^a   Qu, Rui ^a   Liu, Zhiran ^b  

^a HUBEI UNIVERSITY OF MEDICINE   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apoptosis; Peripheral blood mononuclear cells; Sex hormone; Systemic lupus erythematosus

Indexed keywords

DNA; ESTRADIOL; INTERLEUKIN 2; PRASTERONE; SEX HORMONE;

ADULT; APOPTOSIS; ARTICLE; BIOSYNTHESIS; BLOOD; CYTOLOGY; DRUG EFFECT; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MONONUCLEAR CELL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; APOPTOSIS; DEHYDROEPIANDROSTERONE; DNA; ESTRADIOL; FEMALE; GONADAL STEROID HORMONES; HUMANS; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE;

EID: 0035295914     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Jungers P, Nahoul K, Pelissier C, et al. Low plasma androgens in woman with active or quiescent systemic lupus erythematosus. Arthritis Rheum 1982;25:454-457.
2. Suzuki T, Suzuki N, Engleman EG, et al. Low serum levels of dehydroepiandrosterone may cause deficient IL-2 production by lymphocytes in patients with systemic lupus erythematosus (SLE). Clin Exp Immumol 1995;99:251-255.
3. Du QJ, Xiong SZ, Gao QL, et al. Effects of sex hormone on immunity of SLE patients. Chin J Derm Venereol 1994;8:145-146.
4. Herrmann M, Zoller OM, Hagenhofer M, et al. What triggers anti-ds-DNA antibody? Mol Biol Rep 1996;23:265-267.
5. Mevorach D, Zhou JL, Song X, et al. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med 1998;188:387-392.
6. Emlen W, Niebur J, Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol 1994;152:3685-3692.
7. Herrmann M, Lorenz HM, Voll R, et al. A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res 1994;22:5506-5507.
8. van Vollenhoven RF, Engleman EG, McGuire JL. Dehydroepiandrosterone in systemic lupus erythematosus. Results of a double-blind, placebo-controlled, randomized clinical trial. Arthritis Rheum 1995;38:1826-1831.
9. van Vollenhoven RF, Morabito LM, Engleman EG, et al. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. J Rheumatol 1998;25:285-289.
10. Nieto MA, Gonzalez A, Lopez-Rivas A, et al. IL-2 protects against anti-CD3-induced cell death in human medullary thymocytes. J Immunol 1990;145:1364-1368.