MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses

Equine Veterinary Journal

Volumn 33, Issue 2, 2001, Pages 128-136

  Raulo, S M ^a   Sorsa, T ^b   Tervahartiala, T ^b   Pirila E ^b   Maisi, P ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Gelatinases; Horse; Lung; Metalloproteinases; Pulmonary inflammation; Respiratory secretion

Indexed keywords

BIOLOGICAL MARKER; GELATINASE A; GELATINASE B;

ANIMAL; ANIMAL DISEASE; ARTICLE; CASE CONTROL STUDY; CHEMISTRY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYTOLOGY; ENZYMOLOGY; FEMALE; HORSE; HORSE DISEASE; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFLAMMATION; LUNG LAVAGE; MALE; METABOLISM; TRACHEA; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; FEMALE; HORSE DISEASES; HORSES; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG DISEASES, OBSTRUCTIVE; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; TRACHEA;

EID: 0035292798     PISSN: 04251644     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-3306.2001.tb00590.x     Document Type: Article

References (46)

1. Beech, J. (1975) Cytology of tracheobronchial aspirates in horses. Vet. Pathol. 12, 157-164.
2. Bosse, M., Chakir, J., Pouabhia, M., Boulet, L.P., Audette, M. and Laviolette, M. (1999) Serum matrix metalloproteinase-9: Tissue inhibitor of metalloproteinase-1 ratio correlates with steroid responsiveness in moderate to severe asthma. Am. J. Respir. crit. care Med. 159, 596-602.
3. Burnett, D., Afford, S.C., Campbell, E.J., Rios-Mollineda, R.A., Buttle, D.J. and Stockley, R.A. (1988) Evidence for lipid-associated serine proteases and metalloproteases in human bronchoalveolar lavage fluid. Clin. Sci. 75, 601-607.
4. Dixon, P.M. (1992) Respiratory mucociliary clearence in the horse in health and disease, and its pharmaceutical modification. Vet. Rec. 131, 229-235.
5. Dixon, P.M., Railton, D.J. and McGorum, B.C. (1995) Equine pulmonary disease: A case control study of 300 referred cases. Parts 1, 2 and 3. Equine vet. J. 27, 416-435.
6. d'Ortho, M.-P., Jarreau, P.H., Delacourt, C., Macuin-Maviet, I., Levame, M., Pezer, S., Harf, A. and Lafuma, C. (1994) Matrix metalloproteinase and elastase activities in LPS- induced acute lung injury in guinea pigs. Am. J. Physiol. 266, 209-216.
7. Fairbairn, S.M., Page, C.P., Lees, P. and Cunningham, F.M. (1993) Early neutrophil but not eosinophil or platelet recruitment to the lungs of allergic horses following antigen exposure. Clin. expt. Allergy 23, 821-828.
8. Fakuda, Y., Ishizaki, M., Kudoh, S., Kitaichi, M. and Yamanaka. N. (1998) Localization of matrix matalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases. Lab. Invest. 78, 687-698.
9. Finlay, G.A., O'Driscoll, L.R., Russell, K.J., D'Arey, E.M., Masterson, J.B., FitzGerald, M.X. and O'Connor, C.M. (1997a) Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am. J. Respir. crit. care Med. 156, 240-247.
10. Finlay, G.A., Russell, K.J., McMahon, K.J., D'Arey, E.M., Masterson, J.B., FitzGerald, M.X. and O'Connor, C.M. (1997b) Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients. Thorax 52, 502-506.
11. Guttmann, I. and Bergmeyer, H.U. (1994) Determination of urea with glutamate dehydrogenase as indicator enzyme. In: Methods of Enzymatic Analysis, 2nd edn., Ed: H.U. Bergmayer, Academic Press, New York. pp 1797-1798.
12. Huhtala, P., Tuuttila, A., Chow, L.T., Lohi, J., Keski-Oja, J. and Tryggvason, K. (1991) Complete structure of the human gene for 92 kDa type IV collagenase. Divergent regulation of expression for the 92 and 72 kilodalton enzyme genes in HT-1080 cells. J. Biol. Chem. 266, 16485-16490.
13. Kjeldsen, L., Johnsen, A.H., Sengelov, H. and Borregaard, N. (1993) Isolation and primary structure of NGAL. a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268, 10425-10432.
14. Koivunen, A.-L., Maisi, P., Konttinen, Y.T. and Sandholm. M. (1997a) Gelatinolytic activity in tracheal aspirates in horses with chronic obstructive pulmonary disease. Acta vet. Scand. 38, 17-27.
15. Koivunen, A.-L., Maisi, P., Konttinen, Y.T., Prikk, K. and Sandholm. M. (1997b) Collagenolytic activity and its sensitivity to doxycycline inhibition in tracheal aspirates of horses with chronic obstructive pulmonary disease. Acta vet. Scand. 38, 9-16.
16. Laskin, D.L., Soltys, R.A., Berg, R.A. and Riley, D.J. (1994) Activation of alveolar macrophages by native and synthetic collagen-like polypeptides. Am. J. Respir. Cell mol. Biol. 10, 58-64.
17. Leppert, D., Waubant, E., Galardy, R., Bunnett, N.W. and Hauser, S.L. (1995) T Cell gelatinases mediate basement membrane transmigration in vitro. J. Immunol. 154, 4379-4389.
18. Mair, T.S., Stokes, C.R. and Bourne, F.J. (1987) Cellular content of secretions obtained by lavage from different levels of the equine respiratory tract. Equine vet. J. 19, 458-462.
19. Mautino, G., Oliver, N., Chanez, P., Bousquet, J. and Capony, F. (1997) Increased release of matrix metalloproteinase-9 in bronchoalveolar lavge fluid and by alveolar macrophages of asthmatics. Am. J. Respir. Cell mol. Biol. 17, 583-591.
20. McGorum, B.C. and Dixon, P.M. (1994) The analysis and interpretation of equine bronchoalveolar lavage fluid (BALF) cytology. Equine vet. Educ. 6, 203-209.
21. Mellanen, L., Salo, T., Ingman, T., Konttinen, Y.T., Lähdevirta, J. and Sorsa. T. (1998) 72-kDa and 92-kDa gelatinases in saliva of patients with human immunodeficiency virus infection. Acta odont. Scand. 56, 135-142.
22. Mäkelä, M., Larjava, H., Pirilä, E., Maisi, P., Salo, T., Sorsa, T. and Uitto, V.J. (1999) Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes. Expt. Cell Res. 251, 67-78.
23. Naylor, J.N., Clark, E.G. and Clayton, H.M. (1992) Chronic obstructive pulmonary disease: Usefulness of clinical signs, bronchoalveolar lavage, and lung biopsy as diagnostic and prognostic aids. Can. vet. J. 33, 591-598.
24. O'Connor, C.M. and FitzGerald, M.X. (1994) Matrix metalloproteases and lung disease. Thorax 49, 602-609.
25. Ohno, I., Ohtani, H., Nitta, Y., Suzuki, J., Hoshi, H., Honma, M., Isoyama, S., Tanno, Y., Tamura, G., Yamauchi, K., Nagura, H. and Shirato, K. (1997) Eosinophils as a source of matrix matalloproteinase-9 in asthmatic airway inflammation. Am. J. Respir. Cell mol. Biol. 16, 212-219.
26. Okada, Y., Gonoji, Y. Naka, K., Tomita, K., Nakanishi, I., Iwata, K., Yamashita, K. and Hayakawa, T. (1992) Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties. J. Biol. Chem. 267, 21712-21719.
27. Palmgren, M.S., deShazo, R.D. and Carter, R.M. (1992) Mechanisms of neutrophil damage to human alveolar extracellular matrix: The role of serine and metalloproteases. J. Allergy clin. Immunol. 4, 905915.
28. Raulo, S.M. and Maisi, P. (1998) Gelatinolytic activity in tracheal epithelial lining fluid and in blood from horses with Chronic Obstructive Pulmonary Disease. Am. J. vet. Res. 59, 818-823.
29. Raulo, S.M., Sorsa, T. and Maisi, P. (2000) Concentrations of elastinolytic metalloproteinases in respiratory tract secretions of healthy horses and horses with chronic obstructive pulmonary disease. Am. J. vet. Res. 61, 1067-1073.
30. Reynolds, J.J. (1996) Collagenases and tissue inhibitors of metalloproteinases: a functional balance in tissue degradation. Oral Dis. 2, 70-76.
31. Rennard, S.S.I., Basset, G., Lecossier, D., O'Donnel, K.M., Pinkston, P., Martin, P. and Crystal, R.G. (1986) Estimation of volume of epithelial lining fluid recovered by lavage by using urea as a marker of dilution. J. appl. Physiol. 60, 532-538.
32. Riley, D.J., Berg, R.A., Soltys, R.A., Kerr, J.S., Guss, H.N., Curran, S.F. and Laskin, D.L. (1988) Neutrophil response following intratracheal instillation of collagen peptides into rat lungs. Expt. Lung Res. 14, 549-563.
33. Robinson, N.E., Derksen, F.J., Olszewski, M.A. and Buechner-Maxwell. V.A. (1996) The pathogenesis of chronic obstructive pulmonary disease of horses. Br. vet. J. 152, 283-306.
34. Roberts, C.A. (1992) Tracheal wash sampling in the horse. Equine vet. Educ. 4, 266-268.
35. Romanic, A.M. and Madri, J.A. (1994) The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-I dependent. J. Cell Biol. 125, 1165-1178.
36. Roszel, J.F., Freeman, K.P. and Slusher, S.H. (1985) Equine pulmonary cytology. Proc. Am. Ass. equine Practnrs. 31, 171-181.
37. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E. and Seiki, M. (1994) A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370, 61-65.
38. Sepper, R., Konttinen, Y.T., Sorsa, T. and Koski, H. (1994) Gelatinolytic and type IV collagenolytic activity in bronchiectasis. Chest 106, 1129-1133.
39. Sorsa, T., Salo, T., Koivunen, E., Tyynelä, J., Konttinen, Y.T., Bergmann, U., Tuuttila, A., Niemi, E., Teronen, O., Heikkilä, P., Tschesche, H., Leinonen, J., Osman, S. and Stenman, U.H. (1997) Activation of type IV procollagenases by human tumor-associated trypsin-2. J. Biol. Chem. 272, 21067-21074.
40. Stanton, H., Gavrilovic, J., Atkinson, S.J., d'Ortho, M.P., Yamada, K.M., Zardi, L. and Murphy, G. (1998) The activation of proMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MTI-MMP (MMP-14) to a 45 kDa form. J. Cell Sci. 111, 2789-2798.
41. Torii, K., Iida, K.-I. and Miyazaki, Y. (1997) Higher concentrations of matrix metalloproteinases in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome Am. J. Respir. crit. care Med. 155, 43-46.
42. Tremblay, G.M., Ferland, C., Lapointe, J.-M., Vrins, A., Lavoie, J.P. and Cormier, Y. (1993) Effect of stabling on bronchoalveolar cells obtained from normal and COPD horses. Equine vet. J. 25, 194-197.
43. Tulamo, R.-M. and Maisi, P. (1997) Hyaluronate concentration in tracheal lavage fluid from clinically normal horses and horses with chronic obstructive pulmonary disease. Am. J. vet. Res. 58, 729-732.
44. Westerlund, U., Ingman, T., Lukinma, P.-L., Salo, T., Kjeldsen, L., Borregaard, N., Tjäderhane, L., Konttinen, Y.T. and Sorsa, T. (1996) Human neutrophil gelatinase and associated lipocalin in adult and localized juvenile periodontitis. J. dent. Res. 46, 310-319.
45. Winder, N.C., Grünig, G., Hermann, M. and von Fellenberg, R. (1990) Fibrin/fibrinogen in lungs and respiratory secretions of horses with chronic pulmonary disease. Am. J. vet. Res. 51, 945-949.
46. Yao, P.M., Buhler, J.M., d'Ortho, M.P., Lebargy, F., Delclaux, C., Harf, A. and Lafuma, C. (1996) Expression of matrix metalloproteinase A and B by cultured epithelial cells from human bronchial explants. J. Biol. Chem. 271, 15580-15589.