Dopamine D4 receptor (DRD4) polymorphism and adaptability trait during infancy: A longitudinal study in 1- to 5-month-old neonates

Neurogenetics

Volumn 3, Issue 2, 2001, Pages 79-82

  De Luca, Alessandro ^a,d   Rizzardi, Mario ^b   Torrente, Isabella ^a,d   Alessandroni, Rosa ^c   Salvioli, Gian Paolo ^c   Filograsso, Nando ^b   Dallapiccola, Bruno ^d,e   Novelli, Giuseppe ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF URBINO   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Adaptability; Dopamine D4 receptor; Personality; Polymorphism; Temperament

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; DRD4 PROTEIN, HUMAN;

ADAPTIVE BEHAVIOR; ANALYSIS OF VARIANCE; ARTICLE; CAUCASIAN; EXON; FEMALE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; INFANT; ITALY; LONGITUDINAL STUDY; MALE; QUESTIONNAIRE; TEMPERAMENT;

ADAPTATION, PSYCHOLOGICAL; ANALYSIS OF VARIANCE; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FEMALE; GENOTYPE; HUMANS; INFANT; ITALY; LONGITUDINAL STUDIES; MALE; POLYMORPHISM, GENETIC; QUESTIONNAIRES; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; TEMPERAMENT;

EID: 0035291906     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100480100106     Document Type: Article

References (22)

1. Plomin R, Owen MJ, McGuffin P (1994) The genetic basis of complex human behaviours. Science 264:1733-1739
2. Bouchard TJ Jr, Lykken TD, McGue M, Segal NL, Tellegen A (1990) Sources of human psychological differences: the Minnesota study of twins reared apart. Science 250:223-228
3. Ebstein RP, Novick O, Umansky R, Priel B, Osher Y, Blaine D, Bennet ER, Nemanov L, Katz M, Belmaker RH (1996) Dopamine D4 receptor (DRD4) exon III polymorphism associated with the human personality trait of novelty seeking. Nat Genet 12:78-80
4. Benjamin J, Li L, Patterson C, Greenberg BD, Murphy DL, Hamer DH (1996) Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nat Genet 12:81-84
5. Ebstein RP, Levine J, Geller V, Auerbach J, Gritsengo I, Belmaker RH (1998) Dopamine D4 receptor and serotonin transporter promoter in the determination of neonatal temperament. Mol Psychiatry 3:238-246
6. Auerbach J, Geller V, Lezer S, Shinwell E, Belmaker RH, Levine J, Ebstein RP (1999) Dopamine D4 receptor (DRD4) and serotonin transporter promoter (5-HTTLPR) polymorphisms in the determination of temperament in 2-month-old infants. Mol Psychiatry 4:369-373
7. Malhotra AK, Virkunnen M, Rooney W, Eggert M, Linnoila M, Goldman D (1996) The association between the dopamine D4 receptor (DRD4) 16 amino acid repeat polymorphism and novelty seeking. Mol Psychiatry 1:388-391
8. Vandenbergh DJ, Zonderman AB, Wang J, Uhl GR, Costa PT Jr (1997) No association between dopamine D4 receptor exon III seven repeat alleles in Baltimore Longitudinal Study of aging participants. Mol Psychiatry 2:417-419
9. Brazelton TB, Nugent JK (1995) Neonatal Behavioural Assessment Scale. Cambridge University Press, Cambridge
10. Rothbart MK (1981) Measurement of temperament in infancy. Child Dev 52:569-578
11. Medoff-Cooper B, Carey WB, McDevitt SC (1993) The Early Infancy Temperament Questionnaire. J Dev Behav Pediatr 14:230-235
12. Carey WB, McDevitt SC (1978) Revision of the Infant Temperament Questionnaire. Pediatrics 61:735-739
13. Thomas A, Chess S, Birch H (1968) Temperament and behaviour disorders in children. New York University Press, New York
14. Axia G, Prior M, Ferlini L, Condini A (1991) Fattori nel temperamento dei bambini italiani dai 15 ai 35 mesi. Boll Psicologia Applicata 198:41-49
15. Axia G, Prior M, Carelli G (1992) Cross-cultural influences on temperament: a comparison of Italian, Italo-Australian and Anglo-Australian Toddler. Aust Psychol 27:52-56
16. Axia G (1993) La misurazione del temperamento nella prima infanzia. CLEUP, Padova
17. Axia G, Bortolotto A (1995) Questionari per la misurazione del temperamento da 1 a 36 mesi. Nuova edizione. Dipartimento di Psicologia dello sviluppo e della socializzazione. Report 65, Padova
18. Bates JE (1980) The concept of difficult temperament. Merrill-Palmer Quarterly 26:299-319
19. McCabe ERB (1991) Utility of PCR for DNA analysis from dried blood spots on filter paper blotters. PCR Methods Appl 1:99-106
20. Sambroock J, Fritsch EF, Maniatis T (1992) Molecular cloning, a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
21. 4 (DRD4) gene. Hum Mol Genet 2:767-773
22. Gelanter J, Kennedy JL, Van Tol HHM, Civelli O, Kidd KK (1992) The D4 dopamine receptor (DRD4) maps to distal 11p close to HRAS. Genomics 13:208-210