Alkyl ester prodrugs for improved topical delivery of ibuprofen

Indian Journal of Experimental Biology

Volumn 39, Issue 3, 2001, Pages

  Bansal, A K ^a   Khar, R K ^a   Dubey, R ^a   Sharma, A K ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

IBUPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; PRODRUG;

ANIMAL; ARTICLE; CHEMISTRY; EDEMA; RAT; STOMACH ULCER; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; EDEMA; IBUPROFEN; PRODRUGS; RATS; STOMACH ULCER;

EID: 0035288805     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Prodrugs: Metabolism based drug design
2. The role of direct tissue contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats
3. Gastrointestinal intolerance and bleeding with non-narcotic analgesics
4. Non-steroidal anti-inflammatory drugs : Their use in dermatology
5. Carrageenan induced edema in hind paw of rats as an assay for anti-inflammatory drugs
6. Relationship of the enterohepatic cycle to ulcerogenesis in the rat small bowel with flufenamic acid
7. Skin permeability of various non-steroidal anti-inflammatory drugs in man
8. Prodrugs for dermal delivery
9. In vitro evaluation of dermal prodrug delivery - Transport and bioconversion of a series of aliphatic esters of metronidazole
10. Enhancement of in vitro skin permeation of verapamil
11. Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides
12. Effect of primary alcohols on percutaneous absorption
13. Quantitation of activity of alkyl ester prodrugs of ibuprofen