Metabolic changes in rats with photochemically induced cerebral infarction and the effects of batroxobin: A study by magnetic resonance imaging, 1H- and 31P- magnetic resonance spectroscopy

Journal of Traditional Chinese Medicine

Volumn 21, Issue 1, 2001, Pages 59-67

  Guan, Xingzhi ^a   Wu, Weiping ^a   Kuang, Peigen ^a   Kuang, Peizi ^b   Gao, Yang ^b   Guan, Linchu ^b   Li, Liyun ^c   Mao, Xi'an ^c   Liu, Maili ^c  

^a Chinese Military Postgraduate Medical College   (China)

^b INSTITUTE OF PSYCHOLOGY   (China)

^c Chinese Academy of Sciences   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BATROXOBIN; DRUG DERIVATIVE; N ACETYLASPARTIC ACID; N-ACETYLASPARTATE; PHOTOSENSITIZING AGENT; ROSE BENGAL;

ANIMAL; ARTICLE; BRAIN INFARCTION; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTOCHEMISTRY; RANDOMIZATION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ASPARTIC ACID; BATROXOBIN; CEREBRAL INFARCTION; MAGNETIC RESONANCE IMAGING; MALE; PHOTOCHEMISTRY; PHOTOSENSITIZING AGENTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; ROSE BENGAL;

EID: 0035287785     PISSN: 02552922     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Dietrich WD, Watson BD, Busto R,et al. Photochemically induced cortical infarction I. Early microvascular alterations. Acta Neuropathol (Berl), 1987; 72:315-325.
2. Lee ,VM, Burdett NG, Carpenter TA, et al. Evolution of photochemically induced focal cerebral ischemia in the rat: magnetic resonance imaging and histology. Stroke, 1996; 27: 2110-2119.
3. Higuchi T, Graham SH, Fernandez EJ, et al. Effects of severe global ischemia on N-acetylaspartate and other metabolites in the rat brain. Magn Reson Med, 1997; 37: 851-857.
4. De la Torre JC, Butler K, Kozlowski P, et al. Correlates between nuclear magnetic resonance spectroscopy, diffusion weighted imaging, and CA1 morphorrietry following chronic brain ischemia. J Neurosci Res, 1995; 41: 238-245.
5. Sabnders DE, Howe FA, van den Boogaart A, et al. Continuing ischemic damage after acute middle cerebral artery infarction in humans demonstrated by short-echo proton spectroscopy. Stroke, 1995; 26:1007-1013.
6. Lanfermann H, Kugel H, Heindel W, et. al: Metabolic changes in acute and subacute cerebral infarctions: Findings at proton MR spectroscopic imaging. Radiology, 1995; 196: 203-210.
7. Brulatout S,Loubinoux MI, Borredon J, et al. A one-dimensionah (proton and phosphorus) and two-dimensional (proton) in vivo NMR spectroscopic study of reversible global cerebral ischemia J Neurochem, 1990; 66: 2491-2499.
8. Sappey-Marinier D, Chileuitt L, Weiner MW, et al. Hypoglycemia prevents increase in lactic acidosis during reperfusion after temporary cerebral ischemia in rats. NMR-Biomed, 1995; 8 (4): 171-178.
9. Higuchi T, Fernandez EJ, Maudsley AA, et al. Mapping of lactate and N-acetyl-1-aspartate predicts infarction during acute focal ischemia: in vivo 1H magnetic resonance spectroscopy in rats. Neurosurgery, 1996; 38 (1): 121-130.
10. Gyngell ML, Busch E, Schmitz B, et al. Evolution of acute focal cerebral ischaeimia in rats observed by localized 1H MRS, diffusion-weighted MRI, and electrophysiological monitoring. NMR-Biomed, 1995; 8 (5): 206-214.
11. Gillard JH, Barker PB, van Zijl PCM, et al. Protcn MR spectroscopy in acute middle cerebral artery stroke. AJNR Am J Neuroradiol, 1996; 17: 873-886.
12. Wu WP, Kuang PG, Jiang SJ, et al. Effect of batroxobin on expression of c-Jun in left temporal ischemia rats with spatial learning and memory disorder. J. Trad Chin Med, 2000; 20 (2): 83-86.