From Clinical Trials to Real-World Practice: Use of Atypical Antipsychotic Medication Nationally in the Department of Veterans Affairs

Medical Care

Volumn 39, Issue 3, 2001, Pages 302-308

  Rosenheck, Robert ^a,d   Leslie, Douglas ^b   Sernyak, Michael ^c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^d Northeast Program Evaluation Center   (United States)

Author keywords

Cost effectiveness; Medication; Schizophrenia; Systems of care

Indexed keywords

NEUROLEPTIC AGENT;

AMBULATORY CARE; ARTICLE; CLASSIFICATION; CLINICAL PRACTICE; COST CONTROL; DIAGNOSIS RELATED GROUP; DRUG COST; DRUG USE; ECONOMICS; GOVERNMENT; HEALTH SERVICES RESEARCH; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; MENTAL DISEASE; STATISTICS; UNITED STATES; UTILIZATION REVIEW;

AMBULATORY CARE; ANTIPSYCHOTIC AGENTS; COST SAVINGS; DIAGNOSIS-RELATED GROUPS; DRUG COSTS; DRUG UTILIZATION REVIEW; HEALTH SERVICES RESEARCH; HOSPITALIZATION; HUMANS; MENTAL DISORDERS; PATIENT DISCHARGE; PHYSICIAN'S PRACTICE PATTERNS; UNITED STATES; UNITED STATES DEPARTMENT OF VETERANS AFFAIRS;

EID: 0035286571     PISSN: 00257079     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005650-200103000-00010     Document Type: Article

References (19)

1. Rosenheck R, Cramer J, Xu W, et al. A comparison of clozapine and haloperidol in the treatment of hospitalized patients with refractory schizophrenia. N Engl J Med 1997;337:809-815.
2. Tollefson G, Beasley C, Tran P. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective schizophreniform disorders: Results of an international collaborative trial. Am J Psychiatry 1996;154:457-465.
3. Marder S, Meibach R. Risperidone in the treatment of schizophrenia. Am J Psychiatry 1994;151:825-835.
4. Kane J, Honigfeld R, Meltzer H. Clozapine for treatment resistant schizophrenia: A comparison with chlorpromazine. Arch Gen Psychiatry 1998;49:789-796.
5. Essock S, Frisman L, Covell N, et al. Cost-effectiveness of clozapine compared with conventional antipsychotic medication for patients in state hospitals. Arch Gen Psychiatry 2000;57:987-994.
6. Glazer W, Ereshefsky L. A pharmacoeconomic model of outpatient antipsychotic therapy in "revolving door" schizophrenic patients. J Clin Psychiatry 1996;57:337-345.
7. Luchins D, Hanrahan P, Schinderman M, et al. Initiating clozapine treatment in the outpatient clinic: Service utilization and cost trends. Psychiatr Serv 1998;49:1034-1038.
8. Meltzer H, Cola P, Way L, et al. Cost-effectiveness of clozapine in neuroleptic resistant schizophrenia. Am J Psychiatry 1993;150:1630-1638.
9. Revicki D, Luce B, Wechsler J, et al. Cost-effectiveness of clozapine for treatment resistant schizophrenic patients. Hosp Commun Psychiatry 1990;41:850-854.
10. Viale G, Mechling L, Maislin G, et al. Impact of risperidone on the use of mental health care resources. Psychiatr Serv 1997;48:1153-1159.
11. Rosenheck R, Cramer J, Allan E, et al. Cost-effectiveness of clozapine in patients with high and low levels of hospital use. Arch Gen Psychiatry 1999;56:565-572.
12. Wells K. Treatment research at the crossroads: The scientific interface of clinical trials and effectiveness research. Am J Psychiatry 1999;156:5-10.
13. Leslie D, Rosenheck R. Pharmacotherapy of schizophrenia in the Department of Veterans Affairs. West Haven, Conn: Northeast Program Evaluation Center; 1999.
14. Chen R, Nadkami P, Levin F, et al. Using a computer database to monitor compliance with pharmacotherapeutic guidelines for schizophrenia. Psychiatr Serv 2000;51:791-794.
15. Frank R, McGuire T, Normand S, et al. The value of mental health services at the system level: Systems cost effectiveness. Health Aff 1999.
16. Red book: Drug topics red book. Montvale, NJ: Medical Economics Co; 1999.
17. Rosenheck R, Dilella D. National Mental Health Program performance monitoring system: Fiscal year 1999. West Haven, Conn: Northeast Program Evaluation Center; 2000.
18. Desai R, Rosenheck R, Rothbard A. Cross system service use among VA mental health patients in Philadelphia. Admin Policy Mental Health In press.
19. Rosenheck R, Frisman L, Essock S. Impact of VA bed closures on use of state psychiatric services. J Behav Health Serv Res In press.