Syntheses and structure-activity relationships of novel apio and thioapio dideoxydidehydronucleosides as anti-HCMV agents

Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2001, Pages 806-813

  Lak Shin Jeong, ^a   Hea Ok Kim, ^b   Hyung Ryong Moon, ^a   Joon Hee Hong, ^a   Su Jeong Yoo, ^a   Won Jun Choi, ^a   Moon Woo Chun, ^c   Lee, C K ^d  

^a Ewha Womans University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Seoul National University   (South Korea)

^d Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXY 2',3' DIDEHYDRONUCLEOSIDE; 2,3 DIDEOXYRIBOSE; 5 FLUORO 1 (4 HYDROXYMETHYL 2,5 DIHYDROFURAN 2 YL) 1 H PYRIMIDINE 2,4 DIONE; ANTIVIRUS AGENT; APIO DIDEOXYDIDEHYDRONUCLEOSIDE; NUCLEOSIDE DERIVATIVE; OXYGEN; RIBOSE; THIOAPIO DIDEOXYDIDEHYDRONUCLEOSIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL BINDING; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG HYDROLYSIS; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; CELL LINE; CYTOMEGALOVIRUS; DIDEOXYNUCLEOSIDES; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HIV-1; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035282943     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000342f     Document Type: Article

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