Inactivated pronase as the cause of false-positive results of serum cryptococcal antigen tests

Clinical Infectious Diseases

Volumn 32, Issue 5, 2001, Pages 836-837

  Stoeckli, Thomas C ^a,c   Burman, William J ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b DENVER PUBLIC HEALTH   (United States)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PRONASE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIGEN DETECTION; ARTICLE; CLUSTER ANALYSIS; CRYPTOCOCCOSIS; ENZYME INACTIVATION; HUMAN; HUMAN CELL; LABORATORY TEST; LATEX AGGLUTINATION TEST; LUMBAR PUNCTURE; MENINGITIS; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; SEROCONVERSION;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIGENS, FUNGAL; CRYPTOCOCCUS; ENZYME ACTIVATION; FALSE POSITIVE REACTIONS; HUMANS; LATEX FIXATION TESTS; MENINGITIS, CRYPTOCOCCAL; PRONASE; REAGENT KITS, DIAGNOSTIC;

EID: 0035282267     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/319212     Document Type: Article

References (10)

1. Cryptococcal meningitis and AIDS
2. Specificity of the latex-cryptococcal antigen test
3. Detection of a Trichosporon beigelii antigen cross-reactive with Cryptococcus neoformans capsular polysaccharide in serum from a patient with disseminated Trichosporon infection
4. Septicemia due to DF-2: Cause of a false-positive cryptococcal latex agglutination result
5. Control for rheumatoid factors in the latex test for cryptococcosis
6. False-positive reactions in the latex agglutination test for Cryptococcus neoformans antigen
7. False-positive cryptococcal antigen latex agglutination caused by disinfectants and soaps
8. Failure of dithiothreitol and pronase to reveal a false-positive cryptococcal antigen determination in cerebrospinal fluid
9. Comparison of commercial kits for detection of cryptococcal antigen
10. Performance of cryptococcus antigen latex agglutination kits on serum and cerebrospinal fluid specimens of AIDS patients before and after pronase treatment