메뉴 건너뛰기




Volumn 24, Issue 1, 2001, Pages 16-20

Synthesis of 2-(Allylthio)pyrazines As a Novel Cancer Chemopreventive Agent

Author keywords

2 (Allylthio)pyrazine; 2 Mercaptopyrazine; Cancer chemopreventive agents; CYP2E1

Indexed keywords

2 (ALLYLTHIO)PYRAZINE; 2-(ALLYLTHIO)PYRAZINE; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; PYRAZINE DERIVATIVE;

EID: 0035257756     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02976487     Document Type: Article
Times cited : (5)

References (18)
  • 1
    • 0022591843 scopus 로고
    • Heterocyclic amplifiers of phleomycin. X. Derivatives of diazine mono- and dithiols
    • Barlin, G. B., Brown, D. J., Cronin, B. J., and Ngu, M. Heterocyclic amplifiers of phleomycin. X. Derivatives of diazine mono- and dithiols. Aust. J. Chem., 39, 69- 75 (1986).
    • (1986) Aust. J. Chem. , vol.39 , pp. 69-75
    • Barlin, G.B.1    Brown, D.J.2    Cronin, B.J.3    Ngu, M.4
  • 3
    • 0025312821 scopus 로고
    • Tuberculostatics LIII. Substituted dipyrazine disulfide, S-pyrazine esters of 2-pyrazinecarbothioic acid and dipyrazine sulfones
    • Dlabal, K, Palat, K, Machacek, M., and Odlerova, Z. Tuberculostatics LIII. Substituted dipyrazine disulfide, S-pyrazine esters of 2-pyrazinecarbothioic acid and dipyrazine sulfones. Farm. Obz., 59, 249-256 (1990).
    • (1990) Farm. Obz. , vol.59 , pp. 249-256
    • Dlabal, K.1    Palat, K.2    Machacek, M.3    Odlerova, Z.4
  • 6
    • 0028946622 scopus 로고
    • Differential effects of dietary diallyl sulfide and diallyl sulfide on rat intestinal and hepatic drug-metabolizing enzymes
    • Haber, D., Siess. M. -H., Canivenc-Lavier, M. -C., Le Bon, A. M., and Suchetet, M., Differential effects of dietary diallyl sulfide and diallyl sulfide on rat intestinal and hepatic drug-metabolizing enzymes. J. Toxicol. Environ. Hlth., 44, 423-434(1995).
    • (1995) J. Toxicol. Environ. Hlth. , vol.44 , pp. 423-434
    • Haber, D.1    Siess, M.H.2    Canivenc-Lavier, M.C.3    Le Bon, A.M.4    Suchetet, M.5
  • 7
    • 0027377850 scopus 로고
    • Cancer chemoprotection by oltipraz: Experimental and clinical considerations
    • Helzlsouer, K. J. and Kensler, T. W., Cancer chemoprotection by oltipraz: experimental and clinical considerations. Pred. Med., 22, 783-795(1993).
    • (1993) Pred. Med. , vol.22 , pp. 783-795
    • Helzlsouer, K.J.1    Kensler, T.W.2
  • 8
    • 0026577195 scopus 로고
    • Inhibitory effects of diallyl sulfide on the metabolism and tumerogenecity of the tobacco-specific carcinogen 4- (methylnitrosoamine)-1-(3-pyridy1)-1-butanone (NNK) in A/J mouse lung
    • Hong, J. -Y., Wang, T, J., Smith, S., Zhou, S., Pan, J., and Yang, C. S., Inhibitory effects of diallyl sulfide on the metabolism and tumerogenecity of the tobacco-specific carcinogen 4- (methylnitrosoamine)-1-(3-pyridy1)-1-butanone (NNK) in A/J mouse lung. Carcinogenesis., 13, 901-904 (1992).
    • (1992) Carcinogenesis , vol.13 , pp. 901-904
    • Hong, J.Y.1    Wang, T.J.2    Smith, S.3    Zhou, S.4    Pan, J.5    Yang, C.S.6
  • 10
    • 0345557934 scopus 로고
    • Induction of rat hepatic glutathione S transferase by allylsulfide, allylmercaptan and allylmethylsulfide and 2 7allylthiopyrazine
    • (Abstracts of the 7 International Congress of Toxicology, July 2-6, Seattle, WA, U.S.A.) Abstract number, 69-p-8
    • Kim, N, D., Kim, S. G., and Kwak, M. K., Induction of rat hepatic glutathione S transferase by allylsulfide, allylmercaptan and allylmethylsulfide and 2 7allylthio)pyrazine. The International Toxicologists (Abstracts of the 7 International Congress of Toxicology, July 2-6, Seattle, WA, U.S.A.) Abstract number, 69-p-8 (1995).
    • (1995) The International Toxicologists
    • Kim, N.D.1    Kim, S.G.2    Kwak, M.K.3
  • 11
    • 0028219232 scopus 로고
    • Enhanced expression of rat microsomal epoxide hydrolase gene by organo-sulfur compounds
    • Kim, N, D., Kim, S. G., and Kwak, M. K., Enhanced expression of rat microsomal epoxide hydrolase gene by organo-sulfur compounds. Biochem. Pharmacol., 47, 541-547 (1994).
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 541-547
    • Kim, N.D.1    Kim, S.G.2    Kwak, M.K.3
  • 12
    • 0028210888 scopus 로고
    • Initiation of CYP2E1 expression by organosulfur compounds allylsulfide, allylmercaptan and allylmethylsulfide in rats
    • Kim, N, D., Kim, S. G.,Kim, S. G., Kwak, J. Y., Novak, R, F., and Kim, N. D., Initiation of CYP2E1 expression by organosulfur compounds allylsulfide, allylmercaptan and allylmethylsulfide in rats. Biochemical Pharmacology., 47, 531-539(1994).
    • (1994) Biochemical Pharmacology , vol.47 , pp. 531-539
    • Kim, N.D.1    Kim, S.G.2    Kim, S.G.3    Kwak, J.Y.4    Novak, R.F.5    Kim, N.D.6
  • 13
    • 0027325387 scopus 로고
    • The induction of cytochrome P450 2E1 by nitrogen-and sulfur-containing hetrocycles: Expression and molecular regulation
    • Kim S. G. and Novak, R. F., The induction of cytochrome P450 2E1 by nitrogen-and sulfur-containing hetrocycles: expression and molecular regulation. Toxicol. Appl. Pharmacol. 120, 257-265 (1993).
    • (1993) Toxicol. Appl. Pharmacol. , vol.120 , pp. 257-265
    • Kim, S.G.1    Novak, R.F.2
  • 14
    • 0027333128 scopus 로고
    • Evaluation of the post-initiation effects of oltiprax on aflatoxin B1-inducedpreneoplastic foci in a rat model of hepatic tumorigenesis
    • Maxuitenko, Y. Y., Macmillan, D. L., Kensler, T. W, and Roebuck, B. D., Evaluation of the post-initiation effects of oltiprax on aflatoxin B1-inducedpreneoplastic foci in a rat model of hepatic tumorigenesis. Cardnogenesis., 14, 2423-2425(1993).
    • (1993) Cardnogenesis , vol.14 , pp. 2423-2425
    • Maxuitenko, Y.Y.1    Macmillan, D.L.2    Kensler, T.W.3    Roebuck, B.D.4
  • 15
    • 0027527396 scopus 로고
    • Cancer chemopreven tion: Principles and prospects
    • Morse, M. A. and Stoner, G. D., Cancer chemopreven- tion: principles and prospects. Carcinogenesis., 14, 1737- 1746(1993).
    • (1993) Carcinogenesis , vol.14 , pp. 1737-1746
    • Morse, M.A.1    Stoner, G.D.2
  • 16
    • 0027290648 scopus 로고
    • Chemoprevention of colon carcinogenesis by organosulur compounds
    • Reddy, B. S., Rao, C. V, Rivenson, A., and Kelloff, G., Chemoprevention of colon carcinogenesis by organosulur compounds. Cancer Res., 53, 3493-3498 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 3493-3498
    • Reddy, B.S.1    Rao, C.V.2    Rivenson, A.3    Kelloff, G.4
  • 17
    • 0023739534 scopus 로고
    • Effects of organosulfur compounds from garlic and onions on benzo [a]pyrene-induced neoplasia and glutathione-S transfer-ase activity in the mouse
    • Sparmins, V. L, Varany, G., and Wattenberg, L., Effects of organosulfur compounds from garlic and onions on benzo [a]pyrene-induced neoplasia and glutathione-S transfer-ase activity in the mouse. Carcinogenesis., 9, 131-134 (1988).
    • (1988) Carcinogenesis , vol.9 , pp. 131-134
    • Sparmins, V.L.1    Varany, G.2    Wattenberg, L.3
  • 18
    • 0026780968 scopus 로고
    • Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis
    • Wargovich, M. J., Imada, O., and Stephens, L. C., Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis. Cancer Lett., 64, 39-42 (1992).
    • (1992) Cancer Lett. , vol.64 , pp. 39-42
    • Wargovich, M.J.1    Imada, O.2    Stephens, L.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.