A novel formulation for controlled release of heparin-DOCA conjugate dispersed as nanoparticles in polyurethane film

Biomaterials

Volumn 22, Issue 3, 2001, Pages 281-289

  Tae Moon, Hyun ^a   Lee, Yong Kyu ^a   Koo Han, Joon ^b   Byun, Youngro ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Controlled release; Heparin DOCA conjugate; Polyurethane; Solvent casting

Indexed keywords

BIOCOMPATIBILITY; BIOFILMS; BLOOD; COAGULATION; ENZYME IMMOBILIZATION; POLYURETHANES;

ANTICOAGULANT AGENTS; HEPARIN; NANOPARTICLES; SOLVENT CASTING;

CONTROLLED DRUG DELIVERY;

AMPHOPHILE; ANTICOAGULANT AGENT; DEOXYCORTICOSTERONE ACETATE; DIOXANE; HEPARIN; NANOPARTICLE; POLYETHERURETHAN; POLYURETHAN; PROPANOL; SOLVENT; WATER;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DISPERSION; DRUG CONJUGATION; DRUG FORMULATION; DRUG RELEASE; FIBRIN CLOT; FILM; HUMAN; MORPHOLOGY; PARTICLE SIZE; PLASMA; PRIORITY JOURNAL; SCANNING FORCE MICROSCOPY; SURFACE PROPERTY; TECHNIQUE; THICKNESS; THROMBOCYTE ADHESION; WATER TRANSPORT;

DESOXYCORTICOSTERONE; HEPARIN; MICROSPHERES; PARTICLE SIZE; POLYURETHANES; SURFACE PROPERTIES;

EID: 0035255936     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(00)00194-0     Document Type: Article

References (17)

1. Anticoagulant action of heparin
2. Structure and biological activity of heparin
3. Biocompatible materials for use in the vascular system
4. Thromboresistence of bulk heparinized catheters in human
5. In vitro blood compatibility of surface-modified polyurethanes
6. Heparin immobilization onto segmented polyurethaneurea surfaces-effect of hydrophilic spacers
7. Nonthrombogenic plastic surfaces
8. Thrombogenicity of heparin-bound DEAF cellulose hemodialysis membranes
9. Binding of heparin onto ethylene-vinyl alcohol copolymer membrane
10. In vitro biocompatibility evaluation of heparinizable material (PUPA), based on polyurethane and poly(amido-amine) components
11. Development of chitosan/polyethylene vinyl acetate co-matrix; controlled release of aspirin-heparin for preventing cadiovascular thrombosis
12. Poly(vinyl alcohol)-heparin hydrogels as sensor catheter membrane
13. Controlled delivery of therapeutics from microporous membrane
14. Prevention of venous thrombosis in microvascular surgery by transmural release of heparin from a polyanhydride polymer
15. Contrasting effects of the intermittent and continuous administration of heparin in experimental restenosis
16. Local delivery of heparin to balloon angioplasty sites with a new angiolplasty catheter; pharmacokinetics and effect on platelet deposition in the porcine model
17. Preparation of slightly hydrophobic heparin derivatives which can be used for solvent casting in polymeric formulation