Suramin prevents cerebellar granule cell-death induced by dequalinium

Neurochemistry International

Volumn 38, Issue 2, 2001, Pages 135-143

  Chan, Chin Feng ^a   Lin Shiau, Shoei Yn ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Cerebellar granule neurons; Dequalinium; Neurotoxicity; Suramin

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; 6,7 DINITRO 2,3 QUINOXALINEDIONE; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; BROMINE DERIVATIVE; DEQUALINIUM; DIZOCILPINE; FLUORESCEIN DIACETATE; FREE RADICAL; GLUTAMATE RECEPTOR ANTAGONIST; PANCURONIUM; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; SURAMIN; VECURONIUM;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; IMAGE PROCESSING; MALE; MEMBRANE POTENTIAL; MICROFLUOROMETRY; MITOCHONDRIAL MEMBRANE; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL DEATH; CEREBELLUM; DEQUALINIUM; ELECTRIC CONDUCTIVITY; MEMBRANE POTENTIALS; MITOCHONDRIA; NEURONS; NEUROTOXINS; POTASSIUM CHANNELS; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE; RECEPTORS, PURINERGIC P2; SURAMIN;

EID: 0035255285     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(00)00070-X     Document Type: Article

References (22)

1. Glutamate receptors mediate dynamic regulation of nitric oxide synthase expression in cerebellar granule cells
2. Intracellular localization of suramin, an anticancer drug, in human colon adenocarcinoma cells a study by quantitative autoradiography
3. Glia modulate NMDA-mediated signaling in primary cultures of cerebellar granule cells
4. + channels in hepatocytes and of nicotinic responses in skeletal muscle
5. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
6. + channel blockers. Investigations on the role of the charged heterocycle
7. Suramin induced ceramide accumulation leads to apoptotic cell death in dorsal root ganglion neurons
8. Mitochondria and apoptosis
9. Effect of dequalinium on K1735-M2 melanoma cell growth, directional migration and invasion in vitro
10. Inhibition of neointima hyperplasia of mouse vein grafts by locally applied suramin
11. Turnover analysis of glutamate receptors identifies a rapidly degraded pool of the N-methyl-D-aspartate receptor subunit, NR1, in cultured cerebellar granule cells
12. Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis
13. +-channels by methylmercury in rat alveolar macrophages
14. Studies on curare-like action of the tripeptide carbobenzoxy-Gly-Gly-Arg-beta-naphthylamide in mouse diaphragm
15. Mechanisms of growth stimulation by suramin in non-small-cell lung cancer cell lines
16. Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells
17. Activation of c-Jun N-terminal kinase (JNK) by lysophosphatidic acid in Swiss 3T3 fibroblasts
18. Digitonin permeabilization does not affect mitochondrial function and allows the determination of the mitochondrial membrane potential of Trypanosoma cruzi in situ
19. Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation
20. 2+ influx in glial cells is inhibited by glycolytic inhibitors
21. 2+-store in the survival of developing cultured neurons
22. Antioxidants improve impaired insulin-mediated glucose uptake and prevent migration and proliferation of cultured rabbit coronary smooth muscle cells induced by high glucose