Murine B1 B cells require IL-5 for optimal T cell-dependent activation

Journal of Immunology

Volumn 166, Issue 3, 2001, Pages 1531-1539

  Erickson, L D ^a   Foy, T M ^a   Waldschmidt, T J ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD23 ANTIGEN; CD40 ANTIGEN; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN M; INTERLEUKIN 4; INTERLEUKIN 5;

ANIMAL CELL; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE ACTIVATION; B LYMPHOCYTE DIFFERENTIATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HELPER CELL; LYMPHOCYTE PROLIFERATION; NONHUMAN; PERITONEUM CELL; PRIORITY JOURNAL; SPLEEN CELL;

EID: 0035253560     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.3.1531     Document Type: Article

References (50)

1. B-cell activation and maturation to immunoglobulin secretion
2. Immune regulation by CD40 and its ligand GP39
3. B-cell subpopulations and microenvironments
4. The expression of B cell surface receptors. III. The murine low-affinity IgE Fc receptor is not expressed on Ly 1 or 'Ly 1-like' B cells
5. B-cell subsets defined by the FcεR
6. Murine B-cell subsets defined by CD23
7. Differential expression of CD22 (Lyb8) on murine B cells
8. Comparative in vitro analysis of proliferation, Ig secretion, and Ig class switching by murine marginal zone and follicular B cells
9. Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses
10. Switching capacity of FcεRII-positive and -negative murine B cells
11. Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes
12. CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells
13. Signaling through murine CD38 is impaired in antigen receptor-unresponsive B cells
14. Elevated levels of protein kinase C activity and α-isoenzyme expression in murine peritoneal B cells
15. Decreased surface IgM receptor-mediated activation of phospholipase Cγ2 in B-1 lymphocytes
16. Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes
17. B1 and B2 cells differ in their potential to switch immunoglobulin isotype
18. CD40-mediated stimulation of B 1 and B2 cells: Implication in autoantibody production in murine lupus
19. Monoclonal antibodies to murine CD40 define two distinct functional epitopes
20. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent
21. Role of membrane immunoglobulin (Ig) crosslinking in membrane Ig-mediated, major histocompatibility-restricted T cell-B cell cooperation
22. Properties of mouse CD40: Cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies
23. Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion
24. Recombinant CD40 ligand stimulation of murine B cell growth and differentiation: Cooperative effects of cytokines
25. The regulation of T cell-dependent antibody formation in vitro by CD40 ligand and IL-2
26. Induction of germ-line γ1 and εIg gene expression in murine B cells
27. Multivalent, but not divalent, antigen receptor crosslinkers synergize with CD40 ligand for induction of Ig synthesis and class switching in normal murine B cells: A redefinition of the TI-2 vs T cell-dependent antigen dichotomy
28. Interleukin 5 regulation of peritoneal Ly-1 B'lymphocyte proliferation, differentiation and autoantibody secretion
29. 1 to induce S phase entry in B lymphocytes from normal and autoimmune strain mice and in transformed leukemic B cells
30. Cytokines and Ly-1 (B1) B cells
31. + B cells
32. IL-5 receptor positive B cells, but not eosinophils, are functionally and numerically influenced in mice carrying the X-linked immune defect
33. T cell-dependent induction of NK-κB in B cells
34. Cross-linking CD40 on B cells rapidly activates nuclear factor-κB
35. Characterization of CD40 signaling determinants regulating nuclear factor-κB activation in B lymphocytes
36. H transcription, and Ig class switching
37. B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching
38. Different CD40-mediated signaling events require distinct CD40 structural features
39. Membrane-bound CD154, but not CD40-specific antibody, mediates NF-κB-independent IL-6 production in B cells
40. Identification of distinct domains in CD40 involved in B7-1 induction or growth inhibition
41. Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity
42. T cell-dependent antibody production by Ly-1 B cells
43. Antibody response of murine B1 cells to hen eggwhite lysozyme
44. Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production
45. Defective B-1 cell development and impaired immunity against angiostrongylus cantonensis in IL-5Rα-deficient mice
46. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses
47. Mice deficient for the CD40 ligand
48. Humoral immune responses in CD40 ligand-deficient mice
49. The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
50. B cell activation via CD40 is required for specific antibody production by antigen -stimulated human B cells