RNA editing in Trypanosoma brucei: Characterization of gRNA U-tail interactions with partially edited mRNA substrates

Nucleic Acids Research

Volumn 29, Issue 3, 2001, Pages 703-709

  Leung, S S ^a   Koslowsky, D J ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME B558; GUIDE RNA; MESSENGER RNA; PROTOZOAL RNA; PURINE; THYMINE; URIDINE; URIDINE PHOSPHATE;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; GENE DELETION; GENE INSERTION; GENETIC ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; RNA BINDING; RNA CLEAVAGE; RNA EDITING; RNA SEQUENCE; RNA STABILITY; RNA STRUCTURE; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TRYPANOSOMA BRUCEI;

PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0035253519     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.3.703     Document Type: Article

References (27)

1. The mechanism of U insertion/deletion RNA editing in kinetoplastid mitochondria
2. RNA editing in kinetoplastid protozoa
3. Mitochondrial mRNA editing in kinetoplastid protozoa
4. Uridine insertion/deletion RNA editing in trypanosome mitochondria - A review
5. A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information
6. Guide RNAs in kinetoplastid mitochondria have a nonencoded 3′ oligo(U) tail involved in recognition of the preedited region
7. Mapping contacts between gRNA and mRNA in trypanosome RNA editing
8. Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing
9. Distinct differences in the requirements for ribonucleoprotein complex formation on differentially regulated pre-edited mRNAs in Trypanosoma brucei
10. Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates
11. Multiple guide RNAs for identical editing of Trypanosoma brucei apocytochrome b mRNA have an unusual minicircle location and are developmentally regulated
12. Site-specific modification of pre-mRNA: The 2′-hydroxyl groups at the splice sites
13. 3′ end processing of mRNA
14. Native mRNA editing complexes from Trypanosoma brucei mitochondria
15. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
16. RNA draw: An integrated program for RNA secondary structure calculation and analysis under 32-bit Microsoft Windows
17. Developmentally regulated addition of nucleotides within apocytochrome b transcripts in Trypanosoma brucei
18. Mapping the reactive site of ribonuclease P RNA using a substrate containing a photoaffinity agent
19. RNA editing: Transfer of genetic information from gRNA to precursor mRNA in vitro
20. Guide RNA requirement for editing-site-specific endonucleolytic cleavage of preedited mRNA by mitochondrial ribonucleoprotein particles in Trypanosoma brucei
21. Resolution of the RNA editing gRNA-directed endonuclease from two other endonucleases of Trypanosoma brucei mitochondria
22. Brucei RNA editing: Adenosine nucleotides inversely affect U-deletion and U-insertion reactions at mRNA cleavage
23. Trypanosoma brucei U insertion and U deletion activities co-purify with an enzymatic editing complex but are differentially optimized
24. The secondary structure of guide RNA molecules from Trypanosoma brucei
25. Kinetoplastid RNA editing does not require the terminal 3′ hydroxyl of guide RNA, but modifications to the guide RNA terminus can inhibit in vitro U insertion
26. In vitro uridine insertion RNA editing mediated by cis-acting guide RNAs
27. A three-dimensional working model for a guide RNA from Trypanosoma brucei