Overexpressing eukaryotic translation initiation factor 4E stimulates bovine mammary epithelial cell proliferation

International Journal of Biochemistry and Cell Biology

Volumn 33, Issue 2, 2001, Pages 133-141

  Long, Ezhou ^a   Lazaris Karatzas, Anthoula ^b   Karatzas, Costas ^b   Zhao, Xin ^a  

^a MCGILL UNIVERSITY   (Canada)

^b Nexia Biotechnologies Ltd   (Canada)

Author keywords

Bovine mammary epithelial cell proliferation; Overexpressing eukaryotic translation initiation factor 4E

Indexed keywords

ALANINE; COMPLEMENTARY DNA; CYCLIN D1; INITIATION FACTOR 4E; M PROTEIN; MESSENGER RNA; TRYPTOPHAN;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; BREAST EPITHELIUM; CATTLE; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; GENETIC TRANSFECTION; GROWTH RATE; GROWTH REGULATION; NONHUMAN; PROTEIN EXPRESSION; TRANSLATION INITIATION;

ANIMALS; CATTLE; CELL DIVISION; CELL LINE, TRANSFORMED; CYCLINS; EPITHELIAL CELLS; EUKARYOTIC INITIATION FACTOR-4E; FEMALE; GENE EXPRESSION REGULATION; MAMMARY GLANDS, ANIMAL; PEPTIDE INITIATION FACTORS; TRANSFECTION;

BOVINAE; EUKARYOTA; MYCOBACTERIUM AVIUM COMPLEX (MAC);

EID: 0035252453     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(00)00089-3     Document Type: Article

References (27)

1. mRNA 5′ cap-binding protein eIF-4E and control of cell growth
2. Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology
3. Malignant transformation by a eukaryotic factor subunit that binds to mRNA 5′ cap
4. Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates and reduced levels of both eIF-4E and p220 component of eIF-4F
5. Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E
6. Eukaryotic translation initaition factor 4E regulates expression of cyclin D1 at transcriptional and post-transcritptional levels
7. Cyclin D1 in mammary carcinoma
8. Overexpression of cyclin D1 in rat fibroblasts causes abnornalities in growth control, cell cycle progression and gene expression
9. Overexpression of mouse D1-type cyclins accelerates G1 phase in rodent fibroblasts
10. D11S287, a putative oncongene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1
11. Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle
12. Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit
13. Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth
14. Increased expression of cyclin D1 in murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis
15. Establishment of bovine mammary epithelial cells (MAC-T): An in vitro model for bovine lactation
16. Cocrystal structure of the messenger RNA 5′ cap-binding protein (eIF-4E) bound to 7-methyl-GDP
17. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
18. Chapter 7: Extraction, purification, and analysis of messenger RNA from eukaryotic cells
19. Lack of mitogenic response to EGF, pituitary and ovarian hormones in bovine mammary epithelial cells
20. Mechanisms of cyclin-dependent kinase inactivation by progestins
21. Estrogen-dependent cyclin E-cdk2 Activation through p21 redistribution
22. Effects of cyclin E overexpression on cell growth and response to transforming growth factor β depend on cell context and p27kip expression
23. The proto-oncogen/translation factor eIF-4E: A survey of its expression in breast carcinomas
24. Overexpression of the proto-oncogene/translation factor 4E in breast-carcinoma cell lines
25. Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma
26. Role of eIF4E in stimulation of protein synthesis by IGF-I in perfused rat skeletal muscle
27. Increased expression of eukaryotic initiation factor 4E during growth of neonatal rat cardiocytes in vitro