-
1
-
-
0023942517
-
Growth factor receptor tyrosine kinases
-
Yarden Y, Ullrich A: Growth factor receptor tyrosine kinases. Annu Rev Biochem 57:443-478, 1988.
-
(1988)
Annu Rev Biochem
, vol.57
, pp. 443-478
-
-
Yarden, Y.1
Ullrich, A.2
-
2
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
Coussens L, Yang-Feng TL, Iiao Y-C, et al: Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 230:1132-1139, 1985. (Pubitemid 16169997)
-
(1985)
Science
, vol.230
, Issue.4730
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.-C.3
-
3
-
-
0022588467
-
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
-
Yamamoto T, Ikawa S, Akiyama T, et al: Similarity of protein encoded by human c-erbB-2 gene to epidermal growth factor receptor. Nature 319:230-234, 1986 (Pubitemid 16128786)
-
(1986)
Nature
, vol.319
, Issue.6050
, pp. 230-234
-
-
Yamamoto, T.1
Ikawa, S.2
Akiyama, T.3
-
4
-
-
0022406444
-
Amplification of a novel v-erbB-related gene in a human mammary carcinoma
-
King CR, Kraus MH, Aronson SA: Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 229:974-976, 1985. (Pubitemid 16248488)
-
(1985)
Science
, vol.229
, Issue.4717
, pp. 974-976
-
-
King, C.R.1
Kraus, M.H.2
Aaronson, S.A.3
-
5
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, et al: Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-712, 1989. (Pubitemid 19147683)
-
(1989)
Science
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
Press, M.F.11
-
6
-
-
0008677331
-
The expression of the neu oncogene in breast lesions and in normal fetal and adult human tissues
-
De Porer CR, Van Daele S, Van De Vijver MJ, et al: The expression of the neu oncogene in breast lesions and in normal fetal and adult human tissues. Histopathology 15:315-326, 1989.
-
(1989)
Histopathology
, vol.15
, pp. 315-326
-
-
De Porer, C.R.1
Van Daele, S.2
Van De Vijver, M.J.3
-
7
-
-
0025359146
-
Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues
-
Prss MF, Cerdon-Cardo C, Slamon DJ: Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene 5:953-962, 1990.
-
(1990)
Oncogene
, vol.5
, pp. 953-962
-
-
Prss, M.F.1
Cerdon-Cardo, C.2
Slamon, D.J.3
-
8
-
-
0022102126
-
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
-
Drebin JA, Link VC, Stern DF, et al: Down modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell 41:695-706, 1985. (Pubitemid 15243377)
-
(1985)
Cell
, vol.41
, Issue.3
, pp. 695-706
-
-
Drebin, J.A.1
Link, V.C.2
Stern, D.F.3
-
9
-
-
0024478054
-
P185(HER2) monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
-
HER2 monoclonal antibody has antiproliferative effects in vitro and sensitized human breast tumor cells to tumor necrosis factor. Mol Cell Biol 9:1165-1172, 1989. (Pubitemid 19071685)
-
(1989)
Molecular and Cellular Biology
, vol.9
, Issue.3
, pp. 1165-1172
-
-
Hudziak, R.M.1
Lewis, G.D.2
Winget, M.3
Fendly, B.M.4
Shepard, H.M.5
Ullrich, A.6
-
10
-
-
0025986825
-
A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumour cell lines
-
Hancock MC, Langton BC, Chan T, et al: A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumour cell lines. Cancer Res 51:4575-4580, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 4575-4580
-
-
Hancock, M.C.1
Langton, B.C.2
Chan, T.3
-
11
-
-
0026091927
-
Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB2 receptor on tumor growth
-
Stancovski I, Hurwitz E, Leitner O, et al: Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB-2 receptor on tumor growth. Proc Natl Acad Sci USA 88:8691-8695, 1991. (Pubitemid 21915423)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.19
, pp. 8691-8695
-
-
Stancovski, I.1
Hurwitz, E.2
Leitner, O.3
Ullrich, A.4
Yarden, Y.5
Sela, M.6
-
12
-
-
0025752933
-
HER2 and growth inhibition of cells with HER2/neu gene amplification
-
HER2 and growth inhibition of cells with HER2/neu gene amplification. Int J Cancer 47:933-937, 1991.
-
(1991)
Int J Cancer
, vol.47
, pp. 933-937
-
-
Tagliabue, E.1
Centis, F.2
Campiglio, M.3
-
13
-
-
0026664212
-
Monoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonists
-
Harwerth I-M, Wels W, Marte BM, et al: Monoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonists. J Biol Chem 267:15160-15167, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 15160-15167
-
-
Harwerth, I.-M.1
Wels, W.2
Marte, B.M.3
-
14
-
-
0026685034
-
Therapy of an animal model of human gastric cancer using a combination of anti-er6B-2monoclonal antibodies
-
Kasprzyk PG, Song SU, Di Fiore PP, et al: Therapy of an animal model of human gastric cancer using a combination of anti-er6B-2monoclonal antibodies. Cancer Res 52:2771-2776, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 2771-2776
-
-
Kasprzyk, P.G.1
Song, S.U.2
Di Fiore, P.P.3
-
15
-
-
0021999401
-
Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy
-
Schroff RW, Foon KA, Beatty SM, et al: Human antimurine immunoglobulin responses in patients receiving monoclonal antibody therapy. Cancer Res 45:879-885, 1985. (Pubitemid 15161095)
-
(1985)
Cancer Research
, vol.45
, Issue.2
, pp. 879-885
-
-
Schroff, R.W.1
Foon, K.A.2
Beatty, S.M.3
-
16
-
-
0029063864
-
Prolonged survival of mice with human gastric cancer treated with an anti-c-erbB-2 monoclonal antibody
-
Ohnish Y, Nakamura H, Yoshimura M, et al: Prolonged survival of mice with human gastric cancer treated with an anti-c-erbB-2 monoclonal antibody. Br J Cancer 71:969-973, 1995.
-
(1995)
Br J Cancer
, vol.71
, pp. 969-973
-
-
Ohnish, Y.1
Nakamura, H.2
Yoshimura, M.3
-
17
-
-
0022355587
-
Human immune response to multiple injections of murine monoclonal IgG
-
Shawler DL, Bartholomew RM, Smith LM, et al: Human immune response to multiple injection of murine monoclonal IgG. J Immunol 135:1530-1535, 1985. (Pubitemid 16237070)
-
(1985)
Journal of Immunology
, vol.135
, Issue.2
, pp. 1530-1535
-
-
Shawler, D.L.1
Bartholomew, R.M.2
Smith, L.M.3
Dillman, R.O.4
-
19
-
-
0029886350
-
In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product
-
Tokuda Y, Ohnish Y, Shimamura K, et al: In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product. Br J Cancer 73:1362-1365, 1996. (Pubitemid 26175668)
-
(1996)
British Journal of Cancer
, vol.73
, Issue.11
, pp. 1362-1365
-
-
Tokuda, Y.1
Ohnishi, Y.2
Shimamura, K.3
Iwasawa, M.4
Yoshimura, M.5
Ueyama, Y.6
Tamaoki, N.7
Tajima, T.8
Mitomi, T.9
-
20
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D, et al: Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17:2639-2648, 1999. (Pubitemid 29415219)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.9
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
Robert, N.J.4
Scholl, S.5
Fehrenbacher, L.6
Wolter, J.M.7
Paton, V.8
Shak, S.9
Lieberman, G.10
Slamon, D.J.11
-
21
-
-
0032713216
-
Dose escalation and pharmacokinetic study of a humanised anti-HER2 monoclonal antibody in patients with HER2/neu-over-expressing metastatic breast cancer
-
Tokuda Y, Watanabe T, Omuro Y, et al: Dose escalation and pharmacokinetic study of a humanised anti-HER2 monoclonal antibody in patients with HER2/neu-over-expressing metastatic breast cancer. Br J Cancer 81:1419-1425, 1999.
-
(1999)
Br J Cancer
, vol.81
, pp. 1419-1425
-
-
Tokuda, Y.1
Watanabe, T.2
Omuro, Y.3
-
22
-
-
0001793693
-
First-line, non-hormonal, treatment of women with HER2 overexpressing metastatic breast cancer with Herceptin (trastuzumab, humanized anti-HER2 antibody)
-
abstr 275
-
Vogel C, Cobleigh M, Tripathy D, et al: First-line, non-hormonal, treatment of women with HER2 overexpressing metastatic breast cancer with Herceptin (trastuzumab, humanized anti-HER2 antibody). Proc Am Soc Clin Oncol 19:71a, 2000(abstr 275).
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 71a
-
-
Vogel, C.1
Cobleigh, M.2
Tripathy, D.3
-
23
-
-
0033118889
-
Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
-
Pegram M, Hsu S, Lewis G, et al: Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene 18:2241-2251, 1999. (Pubitemid 29186925)
-
(1999)
Oncogene
, vol.18
, Issue.13
, pp. 2241-2251
-
-
Pegram, M.1
Hsu, S.2
Lewis, G.3
Pietras, R.4
Beryt, M.5
Sliwkowski, M.6
Coombs, D.7
Baly, D.8
Kabbinavar, F.9
Slamon, D.10
-
24
-
-
0000405942
-
™ (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2 +/MBC) markedly increase anticancer activity: A randomized multinational controlled phase III trial
-
abstr 377
-
™ (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2 +/MBC) markedly increase anticancer activity: a randomized multinational controlled phase III trial. Proc Am Soc Clin Oncol 17:98a, 1998(abstr 377).
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
, pp. 98a
-
-
Slamon, D.1
Leyland-Jones, B.2
Shak, S.3
-
25
-
-
0001427781
-
Final report: Weekly (W) Herceptin and Taxol (T) for metastatic breast cancer (MBC): Analysis of efficacy by HER2 immunophenotype (immunohistochemistry (IHQ) and gene amplification (fluorescent in-situ hybridization (FISH))
-
abstr 319
-
Seidman A, Fornier M, Esteva F, et al: Final report: weekly (W) Herceptin and Taxol (T) for metastatic breast cancer (MBC): analysis of efficacy by HER2 immunophenotype (immunohistochemistry (IHQ) and gene amplification (fluorescent in-situ hybridization (FISH)). Proc Am Soc Clin Oncol 19:83a, 2000(abstr 319).
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 83a
-
-
Seidman, A.1
Fornier, M.2
Esteva, F.3
-
26
-
-
0000232941
-
Herceptin and vinorelbine for HER22-positive metastatic breast cancer: A phase II study
-
abstr 392
-
Burstein H, Kuter I, Richardson P, et al: Herceptin and vinorelbine for HER22-positive metastatic breast cancer: a phase II study. Proc Am Soc Clin Oncol 19:102a, 2000(abstr 392).
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 102a
-
-
Burstein, H.1
Kuter, I.2
Richardson, P.3
-
27
-
-
0000153682
-
The concordance between the clinical trials assay (CTA) and fluorescence in situ hybridization (FISH) in the Herceptin pivotal trials
-
abstr 291
-
Mass RD, Sanders C, Charlene K, et al: The concordance between the clinical trials assay (CTA) and fluorescence in situ hybridization (FISH) in the Herceptin pivotal trials. Proc Am Soc Clin Oncol 19:75a, 2000(abstr 291).
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 75a
-
-
Mass, R.D.1
Sanders, C.2
Charlene, K.3
-
28
-
-
0001188237
-
Effective HER-2/neu diagnosis in breast cancer by a combination of immunohistochemistry and FISH
-
abstr 294
-
Buehler H, Bangemann N, Evers K, et al: Effective HER-2/neu diagnosis in breast cancer by a combination of immunohistochemistry and FISH. Proc Am Soc Clin Oncol 19:76a, 2000(abstr 294).
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 76a
-
-
Buehler, H.1
Bangemann, N.2
Evers, K.3
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