Modulation of human deoxycytidine kinase activity as a response to cellular stress induced by NaF

Acta Biochimica Polonica

Volumn 48, Issue 1, 2001, Pages 251-256

  Csapó, Zsolt ^a   Sasvári Székely, Maria ^a   Spasokoukotskaja, Tatjana ^a   Staub, Mária ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Deoxycytidine kinase; Lymphocytes; NaF; Tonsil

Indexed keywords

ARA;

DEOXYCYTIDINE KINASE; FLUORIDE SODIUM;

ARTICLE; CELL CULTURE; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; LYMPHOCYTE; METABOLISM; PHOSPHORYLATION; STRESS; TIME; TONSIL;

CELLS, CULTURED; DEOXYCYTIDINE KINASE; ENZYME ACTIVATION; HUMANS; LYMPHOCYTES; PHOSPHORYLATION; SODIUM FLUORIDE; STRESS; TIME FACTORS; TONSIL;

EID: 0035227646     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.2001_5133     Document Type: Article

References (26)

1. Arner, E.S. & Eriksson, S. (1995) Mammalian deoxyribonucleoside kinases. Pharmacol. Ther. 67, 155-186.
2. Datta, N.S., Shewach, D.S., Hurley, M.C., Mitchell, B.S. & Fox, I.H. (1989) Human T-lymphoblast deoxycytidine kinase: Purification and properties. Biochemistry 28, 114-123.
3. Plunkett, W. & Saunders, P.P. (1991) Metabolism and action of purine nucleoside analogues. Pharmacol. Ther. 49, 239-268.
4. Kawasaki, H., Carrera, P.J., Piro, L.D., Saren, A., Kipps, T.J. & Carson, D.J. (1993) Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine. Blood 81, 597-601.
5. Ruiz van Haperen, V.W.T., Veerman, G., Eriksson, S., Boven, E., Stegmann, A.P., Hermsen, M., Vermorken, J.B., Pinedo, H.M. & Peters, G.J. (1994) Development and molecular characterization of a 2′,2′-difluorodeoxycytidine-resistant variant of the human ovarian carcinoma cell line A2780. Cancer Res. 54, 4138-4143.
6. Eriksson, S., Kierdaszuk, B., Munch-Petersen, B., Öberg, B. & Johansson, N.G. (1991) Comparison of substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogues. Biochem. Biophys. Res. Commun. 176, 586-592.
7. Beutler, E. (1992) Cladribine (2-chlorodeoxyadenosine) Lancet 340, 952.
8. Juliusson, G., Elmhorn-Rosenborg, A. & Liliemark, J. (1992) Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. N. Engl. J. Med. 327, 1056-1061.
9. Eriksson S., Arner, E., Spasokoukotskaja, T., Wang, L., Karlsson, A., Brosjö, O., Gunven, P., Julusson, G. & Liliemark, J. (1994) Prospectives and levels of deoxynucleoside kinases in normal and tumor cells: Implications for chemotherapy. Adv. Enzyme Regul. 34, 13-45.
10. Gandhi, V., Estey, E., Keating, M.J., Chucrallah, A. & Plunkett, W. (1996) Chlorodeoxyadenosine and arabinosylcytosine in patients with acute myelogenous leukemia: Pharmacokinetic, pharmaco- dynamic, and molecular interactions. Blood 87, 256.
11. Ooi, K., Ohkube, T., Higashigawa, M., Kawasaki, H. & Sakurai, M. (1996) Increased deoxycytidine kinase activity by etoposide in L1210 murine leucemic cells. Biol. Pharm. Bull. 19, 1382.
12. Datta, N.S., Shewach, D.S., Mitchell, B.S. & Fox, I.H. (1989) Kinetic properties and inhibition of human T lymphoblast deoxycytidine kinase. J. Biol. Chem. 264, 9359-9364.
13. Heinemann, V., Xu, Y.Z., Chubb, S., Sen, A., Hertel, L.W., Grindey, G.B. & Plunkett, W. (1990) Inhibition of ribonucleotide reductase in CCRF-CEM cells by 2′2′-difluorodeoxycytidine. Mol. Pharmacol. 38, 567-572.
14. Sasvári-Székely, M., Piróth, Zs., Kazimierczuk, Z. & Staub, M. (1994) A novel effect of the new antileukemic drug, 2-chloro-2′-deoxyadenosine, in human lymphocytes. Biochem. Biophys. Res. Commun. 203, 1378-1384.
15. Fabianowska-Majewska, K., Tybor, K., Duley, J. & Simmonds, A. (1995) The influence of 2-chloro-2′-deoxyadenosine on metabolism of deoxyadenosine in human primary CNS lymphoma. Biochem.-Pharmacol. 50, 1379-1383.
16. Spasokoukotskaja, T., Sasvári-Székely, M., Taljanidisz, J. & Staub, M. (1992) Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lympocytes. FEBS Lett. 297, 151-154.
17. Xu, Y.Z., Huang, P. & Plunkett, W. (1995) Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts. J. Biol. Chem. 270, 631-637.
18. Hatzis, P., Al-Madhoon, A.S., Jullig, M., Petrakis, T.G., Eriksson, S. & Talianidis, I. (1998) The intracellular localization of deoxycytidine kinase. J. Biol Chem. 273, 30239-30243.
19. Sasvári-Székely, M., Spasokoukotskaja, T., Szöke, M., Csapó, Z., Turi A., Szántó, I., Eriksson, S. & Staub, M. (1998) Activation of deoxycytidine kinase during inhibition of DNA synthesis by 2-chloro-2′-deoxyadenosine (Cladribine) in human lymphocytes. Biochem. Pharmacol. 56, 1175-1179.
20. Spasokoukotskaja, T., Sasvári-Székely, M., Keszler, G., Albertioni, F., Eriksson, S. & Staub, M. (1999) Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity. Eur. J. Cancer 35, 1862-1867.
21. Staub, M., Spasokoukotskaja, T., Taljanidisz, J., Sasvári-Székely, M. & Antoni, F. (1983) Differences between lymphoid organs with respect to the phosphorylation of deoxycytidine and thymidine. Immunology Lett. 6, 137-142.
22. Sasvári-Székely, M., Spasokoukotskaja, T., Soóki-Tóth, Á., Pogány, G., Kopper, L. & Staub, M. (1989). Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors II. ara-C does not inhibit the later process in lymphoid cells. Biochem. Biophys. Res. Commun. 163, 1158-1167.
23. Szyfter, K., Sasvári-Székely, M., Spasokoukotskaja, T., Antoni, F. & Staub, M. (1985) Purification and properties of deoxycytidine kinase. Acta Biochim. Biophys. Acad. Sci. Hung. 20, 173-182.
24. Heinemann, V. & Plunkett, W. (1989) Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6- tetrahydrodeoxyuridine. Biochem. Pharmacol. 38, 4115-4121.
25. Brautigan, D.L. & Shriner, C.L. (1988) Methods to distinguish various types of protein phosphatase activity. Methods Enzymol. 159, 339-346.
26. Wang, L. M. & Kucera, G.L. (1994) Deoxycytidine kinase is phosphorylated in vitro by protein kinase Cα. Biochim. Biophys. Acta 1224, 161-167.