Effects of Mannheimia haemolytica leukotoxin on apoptosis and oncosis of bovine neutrophils

American Journal of Veterinary Research

Volumn 62, Issue 1, 2001, Pages 136-141

  Cudd, Laura A ^a,b   Ownby, Charlotte L ^a   Clarke, Cyril R ^a   Sun, Yude ^a,c   Clinkenbeard, Kenneth D ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b Univ of Colorado Hlth Sci Center ^*  (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINAE; MANNHEIMIA HAEMOLYTICA; PASTEURELLA;

BACTERIAL TOXIN; EXOTOXIN; LEUKOTOXIN; STAUROSPORINE;

ANIMAL; APOPTOSIS; ARTICLE; CATTLE; DRUG EFFECT; ELECTRON MICROSCOPY; IN VITRO STUDY; MANNHEIMIA HAEMOLYTICA; NEUTROPHIL; PATHOLOGY; TIME; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; BACTERIAL TOXINS; CATTLE; EXOTOXINS; MANNHEIMIA HAEMOLYTICA; MICROSCOPY, ELECTRON; NEUTROPHILS; STAUROSPORINE; TIME FACTORS;

EID: 0035226841     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2001.62.136     Document Type: Article

References (27)

1. Yates WDG. A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle. Can J Comp Med 1982;46:225-263.
2. Slocombe RF, Malark J, Ingersoll R, et al. Importance of neutrophils in the pathogenesis of acute pneumonic pasteurellosis in calves. Am J Vet Res 1985;46:2253-2258.
3. Breider MA, Walker RD, Hopkins FM, et al. Pulmonary lesions induced by Pasteurella haemolytica in neutrophil sufficient and neutrophil deficient calves. Can J Vet Res 1988;52:205-209.
4. Shewen PE, Wilkie BN. Evidence for the Pasteurella haemolytica cytotoxin as a product of actively growing bacteria. Am J Vet Res 1985;46:1212-1214.
5. Confer AW, Clinkenbcard KD, Murphy GL. Pathogenesis and virulence of Pasteurella haemolytica in cattle: an analysis of current knowledge and future approaches. In: Donachie W, Lainson FA, Hodgson JC, eds. Haemophilus, actinobacillus, and pasteurella. New York: Plenum Press, 1995;51.
6. Kaehler KL, Markham RJF; Muscoplat CC, et al. Evidence of species specificity in cytocidal effects of Pasteurella haemolytica. Infect Immun 1980;30:615-616.
7. Shewen PE, Wilkie BN. Cytotoxin of Pasteurella haemolytica acting on bovine leukocytes. Infect Immun 1982;35:91-94.
8. Clinkenbeard KD, Mosier DA, Confer AW. Effects of Pasteurella haemolytica leukotoxin on isolated bovine neutrophils. Toxicon 1989;27:797-804.
9. Moayeri M, Welch R. Effects of temperature, time, and toxin concentration on lesion formation by Escherichia coli hemolysin. Infect Immun 1994;62:4124-4134.
10. Czuprynski CJ, Noel EJ. Influence of Pasteurella haemolytica Al crude leukotoxin on bovine neutrophil chemoluminescence. Infect Immun 1990;58:1485-1487.
11. Clinkenbeard KD, Clarke CR, Hague CM, et al. Pasteurella haemolytica leukotoxin-induced synthesis of eicosanoids by bovine neutrophils in vitro. J Leuko Biol 1994;56:644-649.
12. Ortiz-Carranza O, Czuprynski CJ. Activation of bovine neutrophils by Pasteurella haemolytica leukotoxin is calcium dependent. J Leuk Biol 1992;52:558-564.
13. Stevens PK, Czuprynski CJ. Pasteurella haemolytica leukotoxin induces bovine leukocytes to undergo morphologic changes consistent with apoptosis in vitro. Infect Immun 1996;64: 2687-2694.
14. Wyllie AH, Ker JFR, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980;68:251-306.
15. Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995;146:3-15.
16. Trump BF, Berzersky IK. Calcium-mediated cell injury and cell death. FASEBJ 1995;9:219-228.
17. i regulation in apoptosis, oncosis, and necrosis. Biochem Biophys Acta 1996;1313:173-178.
18. Hsuan SL, Kannan MS, Jeyaseelan S, et al. Pasteurella haemolytica Al-derived leukotoxin and endotoxin induce intracellular calcium elevation in bovine alveolar macrophages by different signaling pathways. Infect Immun 1998;66:2836-2844.
19. Murphy GL, Whitworth LC, Clinkenbeard KD, et al. Hemolytic activity of the Pasteurella haemolytica leukotoxin. Infect Immun 1995;63:3209-3212.
20. Cudd LA, Clarke CR, Clinkenbeard KD, et al. Role of intracellular calcium in Pasteurella haemolytica leukotoxin-induced bovine neutrophil leukotriene B4 production and plasma membrane damage. FEMS Micro Lett 1999;172:123-129.
21. Reynolds SE. The use of lead citrate at high pH as an electron opaque stain in electron microscopy. J Cell Biol 1963;17:208-212.
22. Sun Y, Clinkenbeard KD, Clarke CR, et al. Pasteurella haemolytica leukotoxin induces DNA fragmentation in bovine lymphocytes. Vet Micro 1999;65:153-166.
23. Dowd DR. Calcium regulation of apoptosis. Adv Second Messenger Phosphoprotein Res 1995;30:255-280.
24. McConkey DJ, Orrenius S. Signal transduction pathways in apoptosis. Stem Cells 1996;14:619-631.
25. 2+ associated with apoptosis. Meth Cell Biol 1995;46:41-55.
26. Thornberry NA, Bull HG, Calaycay JR, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing on monocytes. Nature 1992;356:768-774.
27. Enari M, Hug H, Nagata S. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 1995;375:78-81.