In vivo pharmacokinetics and anti-anaphylactic activity of the novel mast cell inhibitor 4-(4′-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P131)

American Journal of Therapeutics

Volumn 8, Issue 1, 2001, Pages 35-39

  Malaviya, Ravi ^a  

^a PARKER HUGHES INSTITUTE   (United States)

Author keywords

Allergy; Anaphylaxis; Compound 48 80; Histamine; Mast cells; Pharmacokinetics; WHI P131

Indexed keywords

4 (4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; ANTINEOPLASTIC AGENT; HISTAMINE; QUINAZOLINE DERIVATIVE;

ANAPHYLAXIS; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; DRUG EFFECT; IMMUNOLOGY; INFUSION; MALE; MAST CELL; MOUSE;

ANAPHYLAXIS; ANIMALS; ANTINEOPLASTIC AGENTS; HISTAMINE; INFUSIONS, PARENTERAL; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; QUINAZOLINES;

EID: 0035222466     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/00045391-200101000-00007     Document Type: Article

References (3)

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2. Scharenberg AM, Kinet J-P: Early events in mast cell signal transduction. Chem Immunol 1995;61:72-87.
3. Siraganian RP: Biochemical events in basophil or mast cell activation and mediator release. (1998) In: Allergy, Principles & Practice, 5th ed. (Eds. Middleton E, Reed CE, Ellis EF, Adkinson NF, Junginger JW, Busse WW), Mosby Year Book, Inc., St. Louis, MO, pp204-227.