Relationships between hydrophobicity and algistatic activity of 5-aryl-3H-[1,3,4]oxadiazole-2-thiones

Quantitative Structure-Activity Relationships

Volumn 20, Issue 4, 2001, Pages 291-297

  Schelenz, T ^a   Klunker, J ^a   Bernhardt, T ^a   Schafer W ^a   Dost, J ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; COMPUTATIONAL CHEMISTRY;

BUFFER PH; HYDROPHOBICS; OCTAN-1-OL; OXADIAZOLES; PARTITION COEFFICIENT; PROPERTY; SHAKE-FLASK METHOD; SYNTHESISED; THIONES; WATER BUFFERS;

HYDROPHOBICITY;

1,3,4 OXADIAZOLE DERIVATIVE; 3H [1,3,4]OXADIAZOLE 2 THIONE DERIVATIVE; BUFFER; OCTANOL; UNCLASSIFIED DRUG; WATER;

ALGA; ARTICLE; CALCULATION; CHLORELLA VULGARIS; CORRELATION FUNCTION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHOBICITY; IONIZATION; PARTITION COEFFICIENT; PH; PKA; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 0035218420     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3838(200111)20:4<291::AID-QSAR291>3.0.CO;2-Q     Document Type: Article

References (37)

1. Beziehungen zwischen algistatischer aktivität und physikalisch-chemischen eigenschaften von 5-amino-1aryl-1H-tetrazolen
2. QSAR correlations of the algistatic activity of 5-amino-1-aryl-1H-tetrazoles
3. Zur reaktivität und biologischen aktivität von 2-amino-5-aryl-1,3,4-oxadiazolen
4. Zum substituenteneinfluß auf ausgewählte physikalisch-chemische eigenschaften von 1-acyl-4-arylsemi carbaziden und 3-alkyl-4-aryl-1,2,4-triazolin-5-onen
5. 5-Substituted-1,3,4-oxadiazoles and related compounds as possible fungicides
6. Synthesis of 5-(p-Methoxyphenyl)-1,3,4-oxadiazole-2-thione mannich bases and their biological evaluations
7. Synthesis of 5-aryl/aryloxyalkyl-1,3,4-oxadiazole-2-thiones and related compounds as possible fungicides
8. Combating unwanted vegetation with 2-aryl-5-substituted-1,3,4-oxadiazoles
9. Hypoglycemics. IV. Synthesis and hypoglycemic activity of 5-substituted 1,3,4-oxadiazole derivatives
10. Studies on biologically active heterocycles. Part VI. Synthesis and biological activity of 3,5-disubstituted-1,3,4-oxadiazole-2-thiones and thiophosphate derivatives
11. 5-Substituted-1,3,4-oxadiazoline-2-thiones
12. Synthesis and insecticidal activity of novel 1,3,4-oxadiazolin-5-one and pyrazolin-5-one derivatives
13. Synthesis of 5-aryl-3-(arylamido/imido-alkyl/arylalkyl)oxadiazole-2-thiones as potential hypoglycemic agents
14. Synthesis and pharmacological screening of some new 2 thioxo-3-(substituted aminomethyl)-5-(3,5-dinitrophenyl)1,3,4-oxadiazoles
15. The cyclization of 3 acyldithiocarbazate esters
16. 2-Substituted-1,3,4-oxa- and thia-diazoline-5-thiones
17. Zur chemie der 1,3,4-oxadiazole azoverbindungen auf der grundlage substituierter carbodi hydrazide
18. Partition coefficients and their uses
19. Das chlorella-testsystem
20. Handling and culturing of chlorella
21. Use of distribution coefficients in quantitative structure-activity relationships
22. A new substituent constant, π derived from partition coefficients
23. "Aromatic" substituent constants for structure-activity correlations
24. 2-1,3,4 oxadiazoline-5-thiones
25. Nonadditivity of 1-octanol/water partition coefficients of disubstituted benzenes: An explanation and its consideration in log P estimation
26. Zur physikalisch-chemischen charakterisierung von 5-amino-1-aryl-1h-tetrazolen: Substituenteneffekte bei der verteilung zwischen octan-1-ol und wasser
27. Optimierungsmethoden in der wirkstofforschung - Quantitative struktur-wirkungs-analyse
28. Zur verteilung von 2-amino-5-aryl-1,3,4 oxadiazolen im system n-octanol/wasser
29. Zur verteilung von arylcarbonsäurehydraziden im system n-octanol/wasser
30. Verteilungseigenschaften von aromaten im system n-octanol/wasser; zur verteilung von 4-aryl-scmicarbaziden im system n-octanol/wasser
31. Chemische Struktur und Biologische Aktivität von Wirkstoffen. Methoden der Quantitativen Struktur-Wirkungs-Analyse
32. Homologe serien hydrophober verbindungen im gleichgewicht zwischen einer wäßrigen und einer hydrophoben phase. II. Biologische aktivität und hydrophobe wechselwirkungen mit dem rezeptor
33. Structure-activity relationship in benzamides inhibiting alcohol dehydrogenase
34. Structural dependences of the acid-base properties in six isoelectronic series of 6-π- oxo- and -thioazacyclic compounds