Effect of supplementation of vitamin E and vitamin C on brain acetylcholinesterase activity and neurotransmitter levels in rats treated with scopolamine, an inducer of dementia

Journal of Nutritional Science and Vitaminology

Volumn 47, Issue 5, 2001, Pages 323-328

  Lee, L ^a   Kang, S A ^a   Lee, H O ^a   Lee, B H ^a   Jung, I K ^a   Lee, J E ^a   Heo, Y S ^a  

^a Chung Ang University   (South Korea)

Author keywords

Acetylcholinesterase activity; Neurotransmitter; Scopolamine; Vitamin C; Vitamin E

Indexed keywords

ACETYLCHOLINESTERASE; ALPHA TOCOPHEROL; ASCORBIC ACID; DOPAMINE; NEUROTRANSMITTER; NORADRENALIN; SCOPOLAMINE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DEMENTIA; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; INJECTION; MALE; NONHUMAN; RAT;

ANIMALIA;

EID: 0035215552     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.47.323     Document Type: Article

References (41)

1. Prevalence of dementia in older Japanese-American men in Hawaii. The Honolulu-Asia aging study
2. The prevalence of dementia: A quantitative integration of the literature
3. Dementia among the elderly in a rural Korean community
4. Prevalence of Alzheimer's disease in community population of older persons
5. The prevalence of dementia and Alzheimer's disease in Shanghai, China: Impact of age, gender, and education
6. The epidemiology of Alzheimer's disease
7. Regional distributions of thiobarbituric acid-reactive product, activities of enzymes regulating the metabolism of oxygen free radicals and some of the related enzymes in adult and aged rat brains
8. Lipid peroxides in brain during aging and vitamin E deficiency: Possible relations to changes in neurotransmitter indices
9. Erythrocyte membrane-bound acetylcholinesterase in vitamin E deficient rabbits
10. Decrease of norepinephrine in brain and heart of vitamin E deficient rats
11. Effect of vitamin E intake on levels of vitamin E and C in the central nervous system and peripheral tissues: Implications for health recommendations
12. Effects of chronic haloperidol on vitamin E levels and monoamine metabolism in rats fed normal and vitamin E deficient diets
13. Nigral dopaminergic cell loss in vitamin E deficient rats
14. Turnover of monoamines in hippocampus of rats fed on vitamin E-deficient diet
15. Lipid peroxide formation in rat brain
16. + and water content of brain slices
17. Changes relevant to catecholamine metabolism in liver and brain of ascorbic acid deficient guinea-pigs
18. Effect of ascorbate and cysteine on the 3,4-methylenedioxy-methamphetamine-induced depletion of brain serotonin
19. Ascorbic acid reduces the dopamine depletion induced by MPTP
20. Altered plasma antioxidant status in subjects with Alzheimer's disease and vascular dementia
21. Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Alzheimer's disease
22. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation on the AIN-76A rodent diet
23. Study on the effect of megavitamin E supplementation in man
24. Safety of oral intake of vitamin E
25. Cholinergic learning deficits in the marmoset produced by scopolamine and ICV hemicholinium
26. Effects of vitamin E and vitamin C supplementation on the decrease in cognitive function induced by scopolamine
27. A new and rapid colorimetric determination of acetylcholinesterase activity
28. Rapid automated analysis of biogenic amines and their metabolites using reversed-phase high-performance liquid chromatography with electrochemical detection
29. High dietary intakes of vitamin E and cellular immune functions in rats
30. Measurement of free and bound malondialdehyde in vitamin E-deficient and -supplemented rat liver tissues
31. Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats
32. Experimental vitamin E deficiency in rats Morphological and functional evidence of abnormal axonal transport secondary to free radical damage
33. Longitudinal studies of the neurobiology of vitamin E and other antioxidant systems, and neurological function in the vitamin E deficient rat
34. Effect of different dietary levels of vitamin E on lipid peroxidation in rats
35. Vitamin E protects guinea pig liver from lipid peroxidation without depressing levels of antioxidants
36. Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slices from guinea-pigs fed with vitamin C-deficient diet
37. Effect of vitamin E deficiency on rat brain monoamine metabolism
38. Ascorbate modulates 5-[3H]hydroxy-tryptamine binding to central 5-HT3 sites in bovine frontal cortex
39. The sympathetic nervous system response to stress in chronic vitamin E-deficient rats